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Prospect of personalized medicine places new demands on the evaluation of new medicines

As we enter the era of personalized medicine, it is time to take a fresh look at how we evaluate new medicines and treatments for cancer, according to Donald Berry, Ph.D., professor and chair of the Department of Biostatistics and Applied Mathematics at The University of Texas M. D. Anderson Cancer Center.

6 Jan 2006

Treating gum disease may reduce heart problems

The Journal of Dental Research has just published the results of a study showing that treatment of gum disease may reduce the risk of cardiovascular disease.

5 Jan 2006

Herceptin may work better when it is followed by injections of interleukin

A new study suggests that antibody-based cancer drugs might help patients more if they are given with substances that stimulate the immune system.

5 Jan 2006

NEJM rotavirus studies: statement by PATH's Rotavirus Vaccine Program

On Thursday, January 5, the New England Journal of Medicine published the results of two important clinical trials of rotavirus vaccines.

4 Jan 2006

Reduced rates of lung function decline in cystic fibrosis clinical study patients

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

2 Jan 2006

Vertebroplasty reduces back pain and increases activity levels

A Mayo Clinic study has found patients report less back pain at rest and while active following vertebroplasty, a procedure in which medical cement is injected into painful compression fractures in the spinal vertebrae due to osteoporosis. Patients also reported improved function in their daily activities, such as walking, housework and getting dressed. The findings are published in the November/December issue of American Journal of Neuroradiology.

30 Dec 2005

New drug shows promise in fighting Tuberculosis (TB)

Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberculosis (M. tb).

28 Dec 2005

New drug shows promise in fighting Tuberculosis (TB)

28 Dec 2005

New strategies required to get blacks and Asians to participate in cancer trials

The better informed people are about cancer clinical trials, the more likely they are overall to consider participating in a trial, according to a UC Davis study published in today's issue of the Journal of Clinical Oncology. However, knowing about cancer clinical trials does not appear to increase participation among black and Asian Americans.

21 Dec 2005

Sanofi's human bird flu vaccine tests looking good

French drug company Sanofi Pasteur says early stage trials of an experimental vaccine against H5N1 bird flu have shown it provides a good immune response in humans and is safe.

19 Dec 2005

Common gene variation lessens Tamoxifen’s benefit

Researchers have discovered that one of the most commonly prescribed drugs for breast cancer, tamoxifen, may not be as effective for women who inherit a common genetic variation.

19 Dec 2005

HIV viral load down T-cells up

In her latest update of the 'Case Health - Health Success Stories' website, Cris Kerr features an HIV health success story.

15 Dec 2005

Rockeby Biomed ships first batch of Avian Flu Test kits

Rockeby Biomed has announced that the first batch of its Avian Flu Test kits was sold early this month and shipped to Singapore, North Korea, South Korea, Japan, Romania, Austria, South Africa, Netherlands and UK. The second shipment will be distributed before Christmas.

15 Dec 2005

High cholesterol may lead to high blood pressure in men

Men with high total cholesterol are much more likely to develop high blood pressure than men with low total cholesterol, according to a study in Hypertension: Journal of the American Heart Association.

15 Dec 2005

AMN107 drug shows promise in leukemia resistance to Gleevec

The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.

13 Dec 2005

High-intensity ultrasound waves heats and destroys uterine fibroids

A totally noninvasive procedure using high-intensity ultrasound waves to heat and destroy uterine fibroid tissue significantly relieves fibroid-related symptoms in women, according to the results of a multicenter clinical trial.

7 Dec 2005

New anti-clotting treatment

Volunteers at the Jack and Linda Gill Heart Institute at the University of Kentucky were the first ever to receive a new anti-clotting therapy.

7 Dec 2005

Heart pump technology - comparative study

Chicago's first participant in the RELIANT (Randomized Evaluation of the Novacor(r) LVAS In A Non-Transplant Population) research study recently went home from Northwestern Memorial Hospital.

5 Dec 2005

Mycophenolate mofetil helps treat lupus patients

Treating lupus patients suffering from kidney inflammation with a medicine known as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a new clinical trial indicates.

2 Dec 2005

Risk of severe asthma episodes predicted from fluctuation analysis of airway function

A startling new study published in the science journal Nature this week (Nature Vol 438, issue 7068, pp 667-670) reveals that inhalers used by asthmatics for symptomatic relief of their condition might actually increase the likelihood of an acute attack.

30 Nov 2005