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Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

Chronic stress increases a blood-based hormone called acyl-ghrelin for years after the initial traumatic stressor exposure in some adolescents, and those with elevated levels of the hormone are more likely to develop post-traumatic stress disorder (PTSD) and to experience more severe cases of the condition, according to a study conducted by researchers at the Icahn School of Medicine at Mount Sinai and published August 20 in JAMA Network Open.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

Concussion can lead to long-term sleep problems, affect quality of life

Every year, thousands of people end up in the emergency room or hospital with minor head injuries, often diagnosed as concussions. Concussions usually result from falls, violence, bicycle accidents or sports injuries.

21 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center’s Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.

21 Aug 2020

Broccoli and Brussels could be beneficial in preventing advanced blood vessel disease

New research from Edith Cowan University has shown some of our least favorite vegetables could be the most beneficial when it comes to preventing advanced blood vessel disease.

21 Aug 2020

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

A new federally funded study could reveal the nervous system cells and circuits in our brains that influence our metabolism and health in response to dietary changes.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

COVID-19 causes significant dilation of lung blood vessels, indicates study

A new pilot study from the Icahn School of Medicine at Mount Sinai suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries.

21 Aug 2020

Newly discovered molecule can suppress a wide range of cancers

Scientists at Scripps Research have discovered a molecule that can activate a natural immune-boosting protein called STING.

21 Aug 2020

Anchor entrepreneurship can boost economic growth, shows study

New research from The Business School (formerly Cass) has shed light on how Mirandola, a small town in the North East of Italy, became a major hub for the production of medical devices and sets a roadmap for the origins of industrialisation in small, quiet communities.

21 Aug 2020

Strand-like muscle fibers in the heart tied to heart failure risk

The muscular band of heart tissue called the moderator band or the septomarginal trabecula is found in the right ventricle of the heart and was first described by Leonardo da Vinci in his exploration of human anatomy.

21 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

Genetically engineered mosquitoes to be released in Florida Keys

Mosquitoes are known to be vectors or bearers of several viral and protozoal infections such as dengue, Zika, yellow fever, Chikungunya, and malaria. These infections are known to infect and even kill millions around the world each year. In order to tackle this vector-borne menace, researchers have genetically engineered mosquitoes that could replace the infection carrying species of the mosquitoes.

20 Aug 2020

Study examines the effect of low-carbohydrate, high-fat diet on older adults

A new study, published in Nutrition and Metabolism, from researchers with the University of Alabama at Birmingham's Nutrition Obesity Research Center observed improvements in body composition, fat distribution and metabolic health in response to an eight-week, very low-carbohydrate diet.

20 Aug 2020

Study evaluates the reliability of new serological assays for detecting SARS-CoV-2 antibodies

Approximately four months after the initial description of cases of atypical pneumonia in Wuhan, China, in December 2019, COVID-19 had become a major pandemic threat.

20 Aug 2020

Websites selling home-based COVID-19 testing kits providing inadequate or misleading information

In the UK and US, many websites are selling direct to user self-sampling and testing kits to detect SARS-CoV-2. Recently, a cross-sectional observational study was carried out to check the completeness and accuracy of information provided by these websites.

20 Aug 2020

New SARS-CoV-2 vaccine effective in macaques

Researchers from the biotechnology company Novavax in Gaithersburg, Maryland, have developed a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that successfully induces immunogenicity and protection against the virus in macaques.

20 Aug 2020

COVID-19 could compromise key element of immune response

Researchers at the University of Melbourne have made the unsettling discovery that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might compromise the activation of the CD8+ T-cell responses that would usually ameliorate disease and drive recovery in cases of respiratory disease.

20 Aug 2020

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs.

20 Aug 2020

Blood News and Research

Adolescents with “elevated" hunger hormone are more likely to develop post-traumatic stress disorder

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

Concussion can lead to long-term sleep problems, affect quality of life

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

New York Blood Center receives $15.6 million NIH grant for sickle cell transfusion research

Broccoli and Brussels could be beneficial in preventing advanced blood vessel disease

Study could reveal brain cells and circuits that influence human health and metabolism in response to dietary changes

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

COVID-19 causes significant dilation of lung blood vessels, indicates study

Newly discovered molecule can suppress a wide range of cancers

Anchor entrepreneurship can boost economic growth, shows study

Strand-like muscle fibers in the heart tied to heart failure risk

Using engineered off-the-shelf therapeutic T cells to fight cancer

Genetically engineered mosquitoes to be released in Florida Keys

Study examines the effect of low-carbohydrate, high-fat diet on older adults

Study evaluates the reliability of new serological assays for detecting SARS-CoV-2 antibodies

Websites selling home-based COVID-19 testing kits providing inadequate or misleading information

New SARS-CoV-2 vaccine effective in macaques

COVID-19 could compromise key element of immune response

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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