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Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

News-Medical talks to Mike Greig, Director of Pharma at Bruker, about why measuring collisional cross-sections is beneficial to developing new drugs.

From Bruker Daltonics 10 Feb 2021

Lundquist Institute receives grant to evaluate safety, efficacy of compound for treating psychological distress

The Lundquist Institute has received a $1.75 million grant from the Steven & Alexandra Cohen Foundation to fund a multi-site clinical trial to evaluate the efficacy and safety of the compound psilocybin in individuals with severe psychological distress associated with a terminal medical illness.

10 Feb 2021

Hamilton BiOS® Automated Sample Storage System Selected for New Health Sciences Research Building (HSRB)-II at Emory University

Hamilton Storage is pleased to confirm that the Hamilton BiOS® automated storage system will be installed at Emory University.

From Hamilton Process Analytics 9 Feb 2021

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

A new study provides direct evidence that the oligosaccharides attached to the viral surface spike protein are essential for viral infection, offering new approaches to preventive and therapeutic drugs.

9 Feb 2021

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

An interview with Madeleine Swortwood of Sam Houston State University, on the symposia she will give at Pittcon 2022 about the analytical challenges of cannabis and its impacts on driving and public health.

From Pittcon 9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Could graphene be an effective antiviral platform against SARS-CoV-2?

The urgent need for novel therapeutics has spurred investigation into broad-spectrum inhibitors of viral infection and replication. A new study describes the antiviral activity of synthesized graphene platforms, pointing to new therapeutic approaches against this virus.

8 Feb 2021

Imaging technique can differentiate Alzheimer's disease from dementia with Lewy bodies

Scientists in Portugal and the United Kingdom were able to confirm that an imaging technique that traces neuronal dopaminergic deficiency in the brain is able to differentiate, in vivo, Alzheimer's disease from lesser-known dementia with Lewy bodies.

5 Feb 2021

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Oxygen is essential for human life, but within the body, certain biological environmental conditions can transform oxygen into aggressively reactive molecules called reactive oxygen species (ROS), which can damage DNA, RNA, and proteins.

4 Feb 2021

New molecular voltage sensor helps observe propagation of electrical signals in neurons

A type of novel molecular voltage sensor makes it possible to watch nerve cells at work. The principle of the method has been known for some time. However, researchers at the University of Bonn and the University of California in Los Angeles have now succeeded in significantly improving it.

4 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

A new study describes the antiviral activity of oxysterols, or oxidized cholesterol derivatives, against SARS-CoV-2. These occur in nature, and are not only involved in lipid signaling pathways that modulate a host of processes within the body, including the immune response and lipid homeostasis.

3 Feb 2021

New process separates beneficial glucocorticoids from unwanted side-effects

A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization process they named "ligand class analysis."

3 Feb 2021

Compound News and Research

Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

Lundquist Institute receives grant to evaluate safety, efficacy of compound for treating psychological distress

Hamilton BiOS® Automated Sample Storage System Selected for New Health Sciences Research Building (HSRB)-II at Emory University

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

A precursor to remdesivir shows therapeutic potential for COVID-19

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Could graphene be an effective antiviral platform against SARS-CoV-2?

Imaging technique can differentiate Alzheimer's disease from dementia with Lewy bodies

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

New molecular voltage sensor helps observe propagation of electrical signals in neurons

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

New process separates beneficial glucocorticoids from unwanted side-effects

Scientists discover potential drug target for Hutchinson-Gilford progeria syndrome

Iron release can be detrimental to the heart, study suggests

Zinc supplementation bolsters repurposed antivirals against SARS-CoV-2

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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