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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Placental inflammation's role in adult depression and heart disease

An expression signature related to inflammation expressed in Hofbauer cells in the placenta, calculating polygenic risk scores to predict its expression.

14 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test - a phenomenon known as virologic rebound.

13 Nov 2023

Early life stress circumstances alter more genes in the brain than head injuries

A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.

13 Nov 2023

New drug zilebesiran effectively lowers blood pressure for six months, study finds

A single injection of the experimental medication zilebesiran was safe and effective in reducing systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months, as detailed in the Phase 2 of the KARDIA study, reported as late-breaking science today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Single injection of new medication effectively eliminates Lp(a) for nearly one year

In the first human trial of a new therapeutic, a single injection of lepodisiran reduced levels of lipoprotein(a), or Lp(a), to undetectable levels for nearly one year, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

BioEcho introduces EchoLUTION™ FFPE RNA Kit for superior RNA extraction from FFPE tissues

A leading provider of innovative molecular biology solutions, announces the launch of its EchoLUTION FFPE RNA Kit.

From BioEcho Life Sciences GmbH 13 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

Study shows rhesus macaques as an ideal animal model for studying pelvic organ prolapse

This study is led by Prof. Lan Zhu (Department of Obstetrics and Gynecology, Peking Union Medical College Hospital), Prof. Tao Tan (State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology), and Prof. Weizhi Ji (State Key Laboratory of Primate Biomedical Research, Kunming University of Science and Technology).

10 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

In this groundbreaking study, researchers developed a mucosal adenoviral-vector vaccine, ChAd-SARS-CoV-2-S, which demonstrated sustained and robust immunity against a challenging Omicron variant in nonhuman primates, indicating a promising direction for durable COVID-19 protection strategies. Unlike traditional intramuscular vaccines, this mucosal vaccine elicited a comprehensive immune response, potentially paving the way for more effective and long-lasting COVID-19 vaccines.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

UC Riverside scientists slow progression of Huntington's disease in flies and worms

Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. For the first time, UC Riverside scientists have shown they can slow its progression in flies and worms, opening the door to human treatments.

8 Nov 2023

RNA News and Research

Further Reading

Placental inflammation's role in adult depression and heart disease

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Early life stress circumstances alter more genes in the brain than head injuries

New drug zilebesiran effectively lowers blood pressure for six months, study finds

Single injection of new medication effectively eliminates Lp(a) for nearly one year

BioEcho introduces EchoLUTION™ FFPE RNA Kit for superior RNA extraction from FFPE tissues

Pioneering study finds predictive biomarker in lung adenocarcinoma

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

UCI researchers discover gene critical for muscle repair

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Study shows rhesus macaques as an ideal animal model for studying pelvic organ prolapse

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

Tumor-immune interactions predict treatment responses in multiple myeloma

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis use alters DNA methylation, with implications beyond smoking effects

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

UC Riverside scientists slow progression of Huntington's disease in flies and worms

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