Genomic News and Research

RSS

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Researchers discover new neurological condition characterized by issues with motor coordination and speech

Researchers at the National Institutes of Health have discovered a new neurological condition characterized by issues with motor coordination and speech. They report their findings in npj Genomic Medicine.

10 Feb 2023

Scientists identify miRNAs associated with type 2 diabetes in humans

MicroRNA (miRNA) molecules in pancreatic islets have been thought to play important roles in type 2 diabetes, but until now scientists have not confidently identified which miRNAs are associated with the disease in humans.

10 Feb 2023

No new SARS-CoV-2 variants detected in China since COVID policy change

In a recent study published in The Lancet, researchers reported the trends in coronavirus disease 2019 (COVID-19) cases and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in Beijing in 2022.

9 Feb 2023

Scientists find microRNAs in human pancreatic cells that are strongly linked with type 2 diabetes

In a new large-scale genetic analysis, scientists have found a set of small RNA molecules, called microRNAs, in human pancreatic cells that are strongly associated with type 2 diabetes.

9 Feb 2023

New Zika virus lineages show increased fitness

The current study, published in the journal PLOS Neglected Tropical Diseases, aimed to explore the possible phenotypic adaptation of the Zika virus to increase its transmissibility and virulence in the Americas.

9 Feb 2023

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found.

9 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Increase in resistant Shigella infections among men who have sex with men

Researchers report a rise in Shigella flexneri type 2a infections in men who have sexual intercourse with men in England from September 2021 onward.

7 Feb 2023

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses.

7 Feb 2023

Novel method for comparing whole protein-coding genes between metagenomic data detects an environmental gradient for the microbiota

Researchers from Japan compared phylogenetic trees based on proteomic data of microbiota with dendrograms of environmental factors to determine the role of environmental gradients in establishing microbial communities.

7 Feb 2023

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations.

7 Feb 2023

Researchers identify a new genetic risk factor for age-related macular degeneration

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

6 Feb 2023

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Researchers at the Hong Kong University of Science and Technology developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

3 Feb 2023

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy.

3 Feb 2023

SARS-CoV-2 infections on French mink farms after one year of COVID-19

A new paper, which appears on the bioRxiv* preprint server, describes the investigation of all French mink farms towards the end of 2020. This was to maximize the chances of identifying SARS-CoV-2 infection in these animals at any time over the past year.

3 Feb 2023

Genomic News and Research

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers discover new neurological condition characterized by issues with motor coordination and speech

Scientists identify miRNAs associated with type 2 diabetes in humans

No new SARS-CoV-2 variants detected in China since COVID policy change

Scientists find microRNAs in human pancreatic cells that are strongly linked with type 2 diabetes

New Zika virus lineages show increased fitness

Researchers find possible genetic basis and mouse model for nonalcoholic steatohepatitis

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Increase in resistant Shigella infections among men who have sex with men

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

Novel method for comparing whole protein-coding genes between metagenomic data detects an environmental gradient for the microbiota

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Researchers identify a new genetic risk factor for age-related macular degeneration

Breakthrough technology identifies rare brain tumor cell "spies" disguised as normal cells

Deletion of a tumor suppressor gene promotes luminal breast cancer development and resistance to endocrine therapy

SARS-CoV-2 infections on French mink farms after one year of COVID-19

The relationship between natural plant extracts and SARS-CoV-2

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers develop a cell line to address the challenges facing cellular modeling of disease

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News