Therapeutics News and Research

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New approach offers hope for regaining lost memories in Alzheimer's

While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory.

1 Feb 2024

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The association between biomarkers of cholesterol homeostasis and mortality in critically ill patients.

1 Feb 2024

The anti-cancer potential of sRNAs isolated from different mushroom species

Study reveals that sRNAs from certain mushrooms, particularly Boletus edulis and Agaricus bisporus, show promising anti-cancer properties, with varying efficacy across different species.

31 Jan 2024

Scientists coax a deadly bacterium to destroy itself from the inside out

Northwestern University researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.

31 Jan 2024

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

The neurons that make up our brains and nervous systems mature slowly over many months.

31 Jan 2024

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

A recent study co-authored by Dr. Matthew Segar, a third-year cardiovascular disease fellow at The Texas Heart Institute and led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey, utilized a machine learning-based approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF).

31 Jan 2024

Researchers discover non-opioid therapeutic for relieving neuropathic pain

Among the most difficult types of pain to alleviate is neuropathic pain, pain that is usually caused by damage to nerves in various body tissues, including skin, muscle and joints.

31 Jan 2024

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Members of the AD-RIDDLE consortium announced today that they will begin a new initiative that aims to bridge the gap between Alzheimer's research, implementation science, and precision medicine.

31 Jan 2024

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering from respiratory disease, today announced that it has closed a £26 million ($33.1 million USD) Series B follow-on financing round, led by Panakes Partners.

From Enterprise Therapeutics Ltd 31 Jan 2024

Vitamin D deficiency linked to increased dementia risk, supplements may help

Study in the UK Biobank cohort found vitamin D deficiency and insufficiency significantly increase the risk of dementia, Alzheimer's, and vascular dementia, with supplementation potentially reducing these risks.

30 Jan 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Fermented foods linked to mental health benefits through gut-brain connection

Researchers explore the mental health benefits of fermented foods on the microbiota-gut-brain axis, highlighting the need for further studies to understand their therapeutic potential.

29 Jan 2024

Common biomarker test could be misguiding treatment for some Black women with breast cancer

A common test used to decide whether breast cancer patients should get chemotherapy may be making bad recommendations for some Black women, leading them to forgo chemotherapy when it might have helped, according to new research from the University of Illinois Chicago.

29 Jan 2024

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs.

29 Jan 2024

Asimov launches LV Edge Packaging System to optimize lentivirus production

New off-the-shelf system reduces the cost and risk of lentiviral (LV) production for cell and gene therapy developers.

From Asimov 29 Jan 2024

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

NewsMedical speaks with Chao Ma, Ph.D. a Research Assistant Professor at New York University Tandon School of Engineering, ahead of his presentation at SLAS 2024.

From Society for Laboratory Automation and Screening (SLAS) 29 Jan 2024

Puffed-up MOFs show improved performance as drug-delivery vehicles

The spongelike structure of metal organic frameworks (MOFs) allows these polymers to possibly carry and deliver a range of therapeutic compounds.

27 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn's disease before noticeable symptoms develop.

25 Jan 2024

Therapeutics News and Research

New approach offers hope for regaining lost memories in Alzheimer's

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The anti-cancer potential of sRNAs isolated from different mushroom species

Scientists coax a deadly bacterium to destroy itself from the inside out

Scientists uncover a way to "hack" neurons' internal clocks to speed up brain cell development

Machine learning could personalize diuretic treatment for patients with acute decompensated heart failure

Researchers discover non-opioid therapeutic for relieving neuropathic pain

New initiative aims to transform how Alzheimer's disease is diagnosed, treated across healthcare settings

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Vitamin D deficiency linked to increased dementia risk, supplements may help

Immune protein Ku70 key in fighting bowel cancer

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Fermented foods linked to mental health benefits through gut-brain connection

Common biomarker test could be misguiding treatment for some Black women with breast cancer

Scientists reveal direct link between mitochondrial DNA mutations and cancer treatment response

Asimov launches LV Edge Packaging System to optimize lentivirus production

Dr. Chao Ma: Pioneering 'Leukemia-on-a-Chip' for CAR T Cell Therapy at SLAS 2024

Puffed-up MOFs show improved performance as drug-delivery vehicles

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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