Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

Study reveals new way viruses trigger autoimmunity

Autoimmune diseases such as rheumatoid arthritis and Type 1 diabetes are thought to arise when people with a genetic susceptibility to autoimmunity encounter something in the environment that triggers their immune systems to attack their own bodies.

28 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers-;and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

A broad evaluation of autoimmune disease-associated autoantibodies that have been observed in COVID-19 patients was performed.

22 Feb 2022

The effect of COVID-19 vaccination on long COVID symptoms

Researchers assessed the effectiveness of COVID-19 vaccines in patients experiencing long COVID.

21 Feb 2022

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

In a recent study posted to Preprints with The Lancet* server, a team of researchers from China performed a serology study of thyroid function and antithyroid antibody levels in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-vaccinated recipients and further evaluated their correlation with SARS-CoV-2 neutralizing antibodies (NAbs) levels.

14 Feb 2022

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

In a recent study posted to the Research Square* preprint server, researchers conducted a systematic review to investigate any association between immunoglobulin A (IgA) vasculitis and coronavirus disease 2019 (COVID-19) in children.

8 Feb 2022

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

A new study posted to the medRxiv* preprint server has evaluated the effect of mRNA-based COVID-19 vaccination and boosting strategy on serum antibody responses in PAD patients against the original SARS-CoV-2 strain and circulating variants.

31 Jan 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

In a new study, researchers hypothesized and developed broad-spectrum SARS-CoV-2 inhibitors, ReconnAbs, by modifying the existing non-neutralizing antibodies targeted towards the highly conserved epitopes of the SARS-CoV-2 spike (S) protein combined with a receptor-blocking component.

28 Jan 2022

MU researchers identify highly prevalent mutations specific to Omicron variant

While the Omicron variant continues to infect people around the world, researchers at the University of Missouri have identified the highly prevalent, specific mutations that are causing the Omicron variant's high rate of infection.

22 Jan 2022

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant.

18 Jan 2022

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Researchers determine whether sequences within SARS-CoV-2 could lead to an immune response to autoantigens associated with autoimmune myocarditis.

13 Jan 2022

Macrophages in the arteries can "sniff" out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

13 Jan 2022

Nanovaccines and their immunomodulatory effect against human viruses

A review ]presented the primary progress of nanovaccines against the main viral illnesses.

13 Jan 2022

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers investigate the relationship between the SARS-CoV-2 Omicron variant and immune system based on self/nonself short constituent sequences.

9 Jan 2022

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces.

23 Dec 2021

Study reports that children develop sustained cross-reactive adaptive immunity against coronaviruses

A new study shows that both antibody and cellular arms of the adaptive immune response against SARS-CoV-2 are displayed strong, sustained, and cross-reactive against other coronaviruses, in young children than the immune responses in adults.

23 Dec 2021

University of Birmingham launches 5 new major studies focused on management of type 1 diabetes

The University of Birmingham today announces the launch of five new major studies aimed at improving the prevention, treatment and management of type 1 diabetes – with a particular focus on children and young adults.

17 Dec 2021

Study provides a more effective treatment approach to preventing graft-versus-host-disease

A new study led by UC Davis Health researchers showed that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease (GVHD), an inflammatory condition that develops in patients after their allogeneic hematopoietic stem cell transplantation (allo-HSCT).

16 Dec 2021

Autoimmunity News and Research

Further Reading

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

Study reveals new way viruses trigger autoimmunity

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Spectrum of autoantibodies linked to autoimmune diseases in patients with different COVID-19 clinical outcomes

The effect of COVID-19 vaccination on long COVID symptoms

Study looks at potential impact of BBIBPCorV and CoronaVac SARS-CoV-2 vaccines on thyroid

Assessing the association of COVID-19 and Immunoglobulin A vasculitis in children

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

MU researchers identify highly prevalent mutations specific to Omicron variant

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Macrophages in the arteries can "sniff" out their surroundings and cause inflammation

Nanovaccines and their immunomodulatory effect against human viruses

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers reveal an unrecognized pathway promoting long-term survival of T cells

Study reports that children develop sustained cross-reactive adaptive immunity against coronaviruses

University of Birmingham launches 5 new major studies focused on management of type 1 diabetes

Study provides a more effective treatment approach to preventing graft-versus-host-disease

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