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Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior.

14 Dec 2023

Scientists unlock secret to repairing malnourished children's guts

A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children's underdeveloped gut microbiomes was superior to a widely used standard therapeutic food.

13 Dec 2023

Utilizing firefly liquid handling for laboratory developed tests

In this interview, News Medical speaks with SPT Labtech about utilizing the firefly for Laboratory Developed Tests (LDT), specifically for the field of NGS library prep-based LDT.

From SPT Labtech 13 Dec 2023

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

A Japanese study published in BioRxiv explores the virological characteristics of the SARS-CoV-2 JN.1 variant, finding it has a higher effective reproductive number and stronger resistance to immunity from other variants, potentially due to the L455S spike protein mutation.

11 Dec 2023

Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Genome-wide study shows strong negative correlation between reproduction and lifespan

A University of Michigan-led study based on a review of genetic and health information from more than 276,000 people finds strong support for a decades-old evolutionary theory that sought to explain aging and senescence.

8 Dec 2023

Closing the gender gap in HIV treatment could slash infection rates in Uganda

A study looking at 15 years of HIV transmission and suppression in Uganda reveals how closing gender gaps in treatment could slash infection rates.

8 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Study presents a genome-wide map, "Gnocchi," constructed from 76,156 human genomes, revealing that non-coding regions rich in regulatory elements are crucial in understanding human traits and diseases.

7 Dec 2023

Researchers identify 25 new genetic markers linked to peptic ulcers

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations.

7 Dec 2023

IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

Almost all postmenopausal patients aged 50-69 years with stage I hormone receptor (HR)-positive breast cancer and low scores on a common genetic test who opted out of adjuvant radiotherapy were disease free five years after surgery, according to results from the IDEA clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

7 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Link between gut dysbiosis and chronic diseases explored in new study

Study explores the ecological causes of gut dysbiosis and its link to human diseases, revealing how imbalances in gut microbiota composition, influenced by host-derived factors like oxygen and nitrate, contribute to various chronic conditions.

5 Dec 2023

Study uses game theory to show low tumor heterogeneity leads to higher aggression

A study by the University of the Basque Country (UPV/EHU) uses game theory to establish that tumors with less cellular heterogeneity are more aggressive.

5 Dec 2023

Navigating STXBP1-related disorders: Unraveling clinical and developmental outcomes

Researchers examined the combined patient-years of seizure and developmental histories in individuals with disorders related to the STXBP1 gene.

4 Dec 2023

UK Biobank unveils world's largest genetic data set

In a momentous landmark for medical research, UK Biobank has today [Thursday 30 November] unveiled incredible new data from whole genome sequencing of its half a million participants.

4 Dec 2023

New technique developed to rapidly detect genetic changes in malaria parasites

Scientists have developed a technique to rapidly and reliably detect genetic changes in malaria parasites in Ghana, using just a gaming laptop and portable MinION sequencer from Oxford Nanopore.

4 Dec 2023

CHOP researchers unlock 3D structure of crucial protein for cancer therapy

Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.

1 Dec 2023

Lung-MAP: A beacon of hope for lung cancer patients

The unique public-private partnership that for almost a decade has undergirded the first National Cancer Institute (NCI)-sponsored precision medicine clinical trial in lung cancer can serve as a model for future clinical research that is more rapid, innovative, and inclusive.

1 Dec 2023

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

The risk of Attention Deficit/Hyperactivity Disorder (ADHD) among glucose 6-phosphate dehydrogenase (G6PD)-deficient individuals.

1 Dec 2023

Genomic News and Research

Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behavior, and wellbeing

Scientists unlock secret to repairing malnourished children's guts

Utilizing firefly liquid handling for laboratory developed tests

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

Study identifies targetable fusion RNAs in breast cancer

Genome-wide study shows strong negative correlation between reproduction and lifespan

Closing the gender gap in HIV treatment could slash infection rates in Uganda

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Researchers identify 25 new genetic markers linked to peptic ulcers

IDEA trial: Skipping radiotherapy safe for younger postmenopausal patients with early-stage breast cancer

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Link between gut dysbiosis and chronic diseases explored in new study

Study uses game theory to show low tumor heterogeneity leads to higher aggression

Navigating STXBP1-related disorders: Unraveling clinical and developmental outcomes

UK Biobank unveils world's largest genetic data set

New technique developed to rapidly detect genetic changes in malaria parasites

CHOP researchers unlock 3D structure of crucial protein for cancer therapy

Lung-MAP: A beacon of hope for lung cancer patients

Study reveals G6PD deficiency linked to higher ADHD risk and increased use of stimulant medications

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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