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Glutamate key to unlocking liver regeneration after acute damage

The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, regeneration, which allows it to replace liver cells damaged by the very toxins that these cells eliminate.

26 Mar 2025

New protein target could aid in muscle regeneration for degenerative conditions

For millions of people, losing muscle isn't just about weakness; it's about losing independence. Whether caused by Duchenne muscular dystrophy, aging or other degenerative conditions, muscle loss can make everyday activities – like walking, climbing stairs or even standing up – a daily struggle

26 Mar 2025

Study identifies PDGFRA as a potential target for pediatric high-grade gliomas

Pediatric high-grade gliomas, particularly H3K27M diffuse midline gliomas (DMG), are aggressive malignant brain tumors with a poor prognosis.

26 Mar 2025

Scientists uncover rare gene variants that help people live past 100

Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional longevity. These variants reduce IGF-1 receptor activity through either diminished receptor binding or lower circulating IGF-1 levels.

26 Mar 2025

New targeted therapy shows early success in treating pediatric high-grade gliomas

An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma.

20 Mar 2025

Mediterranean diet shows promise in easing psoriasis, acne, and hidradenitis suppurativa

A recent review highlights how the Mediterranean diet can reduce inflammation and improve outcomes for chronic skin conditions like psoriasis, acne, and hidradenitis suppurativa by modulating key inflammatory pathways and supporting metabolic health.

19 Mar 2025

Moffitt researchers discover new vaccine strategy for treating specific type of breast cancer

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer.

18 Mar 2025

Can yogurt and kefir help prevent osteoporosis? Scientists examine the facts

Fermented dairy products and probiotics may support bone health by enhancing calcium absorption, modulating inflammation, and influencing bone remodeling, though human studies show mixed results.

18 Mar 2025

Lymph node transfer proven effective for lymphedema after breast cancer surgery

A multicenter study led from Finland has shown that lymph node transfer is a viable treatment for the swelling in the affected limb, a condition known as lymphedema, after breast cancer surgery.

18 Mar 2025

Yale research supports MRD detection for post-treatment lung cancer care

In the continuing evolution of personalized medicine, a new Yale study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer years after their treatment.

17 Mar 2025

New therapeutic approach shows promise for pediatric high-grade gliomas

Brain tumors remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than 18 months after diagnosis and limited treatment options.

14 Mar 2025

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19. Blocking TGFβ may offer a potential new treatment for this life-threatening condition.

13 Mar 2025

Researchers identify cause of post-COVID inflammatory shock in children

MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening.

12 Mar 2025

Study sheds light on the role of fibro-adipogenic progenitors in muscle regeneration and degeneration

A recent study has shed new light on the role of fibro-adipogenic progenitors (FAPs) in muscle regeneration, fibrosis, and degeneration.

5 Mar 2025

Artificial ligaments could revolutionize ACL surgery and recovery

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

27 Feb 2025

Hormones may offer new way to treat wrinkles and hair graying

Hormones may be leveraged to treat and prevent signs of aging such as wrinkles and hair graying, according to a new study published in the Endocrine Society journal Endocrine Reviews.

26 Feb 2025

Water-only fasting boosts human growth hormone without weight loss

Fasting for 24 hours increases human growth hormone (HGH) levels independently of weight loss, with individuals with lower baseline HGH experiencing the most significant increases. The study suggests metabolic benefits from fasting, particularly for those with lower HGH levels.

25 Feb 2025

FGF21 hormone drives protein-specific appetite and reward in the brain

When faced with multiple food options and ultimately choosing one, the factors of that decision-making process may be more physiological than previously assumed.

25 Feb 2025

New mechanism uncovered to combat therapy-resistant cancer cells

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered a mechanism that opens up new treatment strategies for tumors in which conventional chemotherapeutic agents have reached their limits.

25 Feb 2025

Study uncovers pathway behind age-related degeneration of eye glands

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function.

24 Feb 2025