Jet Lag News and Research

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Jet lag, medically referred to as "desynchronosis," is a physiological condition which is a consequence of alterations to circadian rhythms; it is classified as one of the circadian rhythm sleep disorders.

Jet lag disrupts sleep by throwing two neural centers out of sync

New research by scientists in the U.S. has revealed that the disrupted sleep which results from jet lag and shift work occurs in two separate but linked groups of neurons below the hypothalamus at the base of the brain.

19 Apr 2009

Jet lag disturbs sleep by upsetting internal clocks in 2 neural centers

Jet lag is the bane of many travelers, and similar fatigue can plague people who work in rotating shifts.

16 Apr 2009

Researchers model 3D structures of proteins that control human clock

In an Early Edition issue of The Proceedings of the National Academy of Sciences (PNAS) on April 9, 2009, the researchers report that they have been able to determine the molecular structure of a plant photolyase protein that is surprisingly similar to two cryptochrome proteins that control the "master clock" in humans and other mammals.

12 Apr 2009

New sleeping pill could be the answer to jet lag

An experimental drug developed by Australian scientists could offer a new cure for jet lag and be a welcome alternative to addictive sedatives such as benzodiazepines.

3 Dec 2008

New drug tasimelteon may cure jet lag

A team of researchers from Monash University, The Brigham and Women's Hospital (Boston), Harvard Medical School and Vanda Pharmaceuticals has found a new drug with the potential to alleviate jet lag and sleep disorders caused by shift work.

3 Dec 2008

New dimension discovered in body clock rhythm

Research on what makes the body clock tick has led Dr Michael Hastings of the MRC Laboratory of Molecular Biology in Cambridge to discover a new and unanticipated cog in the human body clock. A patent for the compound involved has been filed by MRC Technology. The results, published in Science, could lead to therapies for people whose sleep is disrupted by shift work or old age.

18 May 2008

Boffins admit to using drugs to enhance their thinking

A survey of readers of a scientific journal has revealed that one in five use drugs to enhance their thinking.

9 Apr 2008

Release of blood stem cells from bone marrow is regulated by brain through human biological clock

These new findings, published online on the website of the journal Nature, point out that the harvest of stem cells for transplantation may be improved by timing it at the peak of their release.

7 Feb 2008

Melatonin could actually be hurting you at night!

What do you do when a naturally occurring hormone in your body turns against you? What do you do when that same hormone - melatonin - is a popular supplement you take to help you sleep?

16 Nov 2007

Practice parameters discuss the evaluation, treatment of circadian rhythm sleep disorders

Practice parameters published in the November 1 issue of the journal SLEEP are a guide to the appropriate assessment and treatment of circadian rhythm sleep disorders (CRSDs).

2 Nov 2007

New mathematical models for circadian rhythm

The internal clock in living beings that regulates sleeping and waking patterns -- usually called the circadian clock -- has often befuddled scientists due to its mysterious time delays.

28 Aug 2007

Sildenafil increases release of key reproductive hormone oxytocin

Researchers at the University of Wisconsin-Madison report this month that sildenafil increases the amount of oxytocin released by stimulation of the posterior pituitary gland, a small structure directly underneath the brain that regulates hormone levels in response to neural signals.

24 Aug 2007

It may be 'altitude sickness' rather than jet lag but you still feel rotten

A study has revealed that many of the effects of long-distance flight which are usually put down to jet lag and fatigue, may in fact be altitude sickness.

5 Jul 2007

RAS signaling of circadian output

In the June 15th issue of G&D, Drs. Jay Dunlap and Jennifer Loros, with colleagues at Dartmouth Medical School, have finally cloned the band gene, and have found that it is an allele of ras-1.

17 Jun 2007

New findings on jet lag

Circadian clocks regulate the timing of biological functions in almost all higher organisms.

24 May 2007

Circadian clock gene plays role in weight gain

Scientists at the University of Virginia and the Medical College of Wisconsin have discovered that a gene that participates in the regulation of the body's biological rhythms may also be a major control in regulating metabolism.

18 May 2007

What makes a simple biological clock tick?

An interdisciplinary team of researchers at Vanderbilt University has analyzed the simplest known biological clock and figured out what makes it tick.

3 Apr 2007

Actigraphy helps assess and manage sleep disorders

Actigraphy, the use of a portable device that records movement over extended periods of time, and has been used extensively in the study of sleep and circadian rhythms, provides an acceptably accurate estimate of sleep patterns in normal, healthy adult populations and in-patients suspected of certain sleep disorders, according to practice parameters published in the April 1st issue of the journal SLEEP.

2 Apr 2007

Jet lag could be a killer

Researchers in the U.S. have found that jet lag or rotating shift work shortens the lifespan in mice and they say it raises concerns for humans affected by time disruption.

7 Nov 2006

New genetic findings relating to the tau mutation

The first gene known to control the internal clock of humans and other mammals works much differently than previously believed, according to a study by Utah and Michigan researchers.

3 Jul 2006