Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Large animals with ailing livers can grow new organ in lymph nodes from their own hepatocytes

Hepatocytes -- the chief functional cells of the liver -- are natural regenerators, and the lymph nodes serve as a nurturing place where they can multiply.

24 Aug 2020

Acidic niche within lymph nodes plays integral role in regulating T cell activation

In the fight against cancer, the immune system is the first line of defense. The lymphatic system specifically is essential to protecting the body against foreign invaders.

19 Aug 2020

Scientist explains why COVID-19 targets only some organs while others are spared

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the enzyme angiotensin-converting enzyme 2 (ACE2) to enter and infect human cells. It causes COVID-19 and can lead to a multitude of complications, including multi-organ impairment, partially due to the abundant expression of ACE2 in all human tissues.

11 Aug 2020

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Today's Food and Drug Administration approval of the first CAR T-cell therapy for mantle cell lymphoma represents a key advance for patients with relapsed or treatment-resistant forms of the disease, say Dana-Farber Cancer Institute investigators who helped conduct the decisive clinical trial of the therapy.

24 Jul 2020

Enhanced photoacoustic imaging improves cancer staging

Prof. TIAN Chao's group from the Department of Precision Machinery and Instrumentation, University of Science and Technology of China of the Chinese Academy of Sciences has made progress on the photoacoustic imaging for medical science.

29 Jun 2020

New radiopharmaceutical shows excellent imaging performance in tumor detection

For neuroendocrine cancer patients with liver metastases, a new radiopharmaceutical, 68Ga-DOTA-JR11, has shown excellent imaging performance in tumor detection, staging, and restaging, providing important information to guide treatment.

26 Jun 2020

Study: Breast cancer reduction efforts show mixed progress

The data is clear: for patients with early stage breast cancer, certain operations risk more harm than good -; increasing the risk of medical complications, missed work and health care costs without increasing survival rates.

10 Jun 2020

Fraunhofer researchers investigate the mechanisms of metastasis formation

What makes tumor cells turn murderous? The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is investigating the mechanisms of metastasis formation - and searching for approaches for new treatments in the fight against cancer.

2 Jun 2020

Lymph node and distant metastases develop through different evolutionary mechanisms, study shows

The evolutionary processes underlying metastasis-the development of secondary malignant growths away from the primary tumor site-in human patients are still incompletely understood.

26 May 2020

Prellis Externalized Human Immune System produces human antibodies against SARS-Cov2

Prellis Biologics, Inc. today announced that it has generated 300 human IgG antibodies that bind to either the S1 or S2 spike protein of the SARS-CoV2-Wuhan strain of the novel coronavirus.

20 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Researchers show basic lymphatic vessel functionality is the same in mice and humans

In an international collaboration, researchers from Uppsala University have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells.

5 May 2020

ATS publishes first official clinical practice guidelines for sarcoidosis

New guidance is available for physicians who must go through a number of steps to provide a probable diagnosis of sarcoidosis - an inflammatory disease that affects the lungs, lymph glands, and other organs.

20 Apr 2020

New prognostic tool could help improve clinical decision making for leukemia patients

A new prognostic tool predicts how long someone diagnosed with chronic lymphocytic leukemia (CLL) will be able to wait before starting cancer treatment.

8 Apr 2020

New prognostic tool helps leukemia patients plan for cancer treatment

A prognostic tool predicts how long someone diagnosed with chronic lymphocytic leukemia (CLL) can wait before cancer treatment.

8 Apr 2020

Research suggests potential treatment target to slow lymphoma tumor growth

Researchers at the MDC observe the very early stages of blood vessel development in lymph node tumors.

7 Apr 2020

Research offers hope for increasing the robustness of vaccine response in older people

Research just published by the Linterman lab shows that the immune system of older mice can be given a helping hand by applying immunology expertise and some genital wart treatment (don't try this at home just yet)!

27 Mar 2020

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A study by investigators at Hospital for Special Surgery has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease.

22 Mar 2020

Technology effectively detects harsh side effect of breast cancer treatment

Some 20 percent of breast cancer survivors will suffer from lymphedema, a potentially severe side effect of treatment that makes arms swell with lymph. The disease is often overlooked, but commercially available app-based technology now makes early detection easier, allowing for proactive treatment.

16 Mar 2020

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

The cover for issue 10 of Oncotarget features Figure 3, "Overall survival (OS) for high (red) versus low (black) risk groups in the (A) OSU, (B) TCGA, and (C) SNU resected cohorts," by Wolfe, et al.

13 Mar 2020