Metabolic Disease News and Research

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Xylitol linked to higher risk of cardiovascular events, Cleveland Clinic study finds

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

7 Jun 2024

Critical role of protein-lipid interactions in mitochondrial energy production revealed

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

7 Jun 2024

Higher amounts of sugar alcohol xylitol associated with increased risk of cardiovascular events

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

6 Jun 2024

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

A recent study in BMC Medicine found that type 2 diabetes significantly increases the risk of various cancers, with the risk being even higher in patients with diabetic retinopathy (DR).

2 Jun 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Opioid receptors play unexpected role in gut nervous system development

Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut."

29 May 2024

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.

28 May 2024

From research to practice: Closing the divide in obesity management

As research continues to produce evidence about the underlying causes of obesity and optimal strategies to treat and manage obesity have evolved, there are disparities in application of the latest scientific advances in the clinical care that people with obesity receive.

20 May 2024

Body fat percentage beats BMI in predicting obesity-related health risks, study says

A study in the Journal of Clinical Endocrinology & Metabolism found that body fat percentage (%BF) thresholds are more accurate than BMI for predicting obesity-related health conditions, suggesting new standards for defining overweight and obesity.

19 May 2024

Research identifies a unique protein fingerprint linked to very short sleep and increased diabetes risk

Study highlights the association between sleep duration and proteomic fingerprints, finding that very short sleep is linked to proteins involved in inflammation and cell death that increase the risk of diabetes mellitus (DM) but not coronary heart disease (CHD).

1 May 2024

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

23 Apr 2024

Eating Mediterranean-style during pregnancy linked to healthier moms and babies

Systematic review and meta-analysis investigates the impact of the Mediterranean diet during pregnancy on perinatal health, showing significant benefits in reducing gestational diabetes and improving birth outcomes.

11 Apr 2024

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

study reveals that SGLT2 inhibitors consistently lower the risk of major adverse cardiovascular events by 9% across various patient groups, especially impacting cardiovascular death reduction, highlighting their broad therapeutic potential beyond diabetes management.

9 Apr 2024

Genetic link between PTSD and Alzheimer's debunked in veterans study

Study reveals that the genetic risk factor for Alzheimer’s disease, APOE ε4, does not increase PTSD risk among combat veterans, challenging the previously suggested link between PTSD and future dementia.

7 Apr 2024

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

Argininosuccinate lyase deficiency (ASLD), also known as argininosuccinic aciduria, is a disease that has been enriched in the Finnish genetic heritage.

4 Apr 2024

How gut microbiome influences obesity onset differently in men and women

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May) identifies changes in the composition of gut bacteria that may play a key role in the onset and development of obesity, with differences in men and women, which might affect the metabolism of different nutrients and therefore the presence of bioactive molecules in the gut that influence the development of metabolic disease.

2 Apr 2024

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade.

2 Apr 2024

Study examines meat consumption's impact on mortality risk in the frail

How meat consumption influences the risk of death in frail populations.

29 Mar 2024

Antioxidant-rich diets linked to lower type 2 diabetes risk, supplements less effective

Study systematically reviews the impact of dietary antioxidants, vitamins C, E, and beta-carotene, on reducing the risk of type 2 diabetes, suggesting an inverse association with the disease, though no protective effects from supplementation were observed.

26 Mar 2024

GRADE study reveals key findings in diabetes medication efficacy

Diabetes affects more than 1 in 10 - or more than 38 million - Americans. People with diabetes who keep their blood sugar levels in the near-normal range generally have a much lower risk of developing diabetes complications such as heart, kidney, and eye diseases.