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Neural circuit mechanisms explain how chronic sleep loss disrupts social memory

Social memory—the ability to recognize familiar individuals and distinguish them from strangers—is fundamental to social cognition.

5 Mar 2026

New collaboration explores familial inflammatory bowel disease in Saudi Arabia

Mount Sinai and King Saud University Medical City in Riyadh, Saudi Arabia, today announced a three-year collaboration aimed at better understanding why inflammatory bowel disease (IBD) runs in some Saudi families, and how that knowledge can lead to risk ascertainment, earlier diagnosis and more personalized treatment options.

3 Mar 2026

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research published in The Journal of Nuclear Medicine.

27 Feb 2026

New biomarkers for targeted gastric therapy

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity compared with earlier agents, most patients either fail to respond initially or eventually develop resistance.

26 Feb 2026

Serial liquid biopsies reveal evolution in advanced prostate cancer

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.

26 Feb 2026

Imaging technique can objectively identify a recently recognized type of dementia, LATE

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

26 Feb 2026

Georgia State experts to play a key role in the largest study of profound autism

Experts from the Translational Research in Neuroimaging and Data Science (TReNDS) Center at Georgia State University will play a key role in the largest study ever conducted to investigate the causes of profound autism in children and develop possible treatments.

26 Feb 2026

ATG14 found to be a critical defender against hepatic injury and fibrosis

Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific role of Autophagy Related 14 (ATG14) in liver health has remained unclear.

24 Feb 2026

Oxytocin circuits mediate sleep loss-induced social memory deficits

Social memory-the ability to recognize familiar individuals and distinguish them from strangers-is fundamental to social cognition.

23 Feb 2026

Engineers develop highly precise gene editor for safer cystic fibrosis treatments

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic "base pairs" to a new level of precision, opening the door to safer, more reliable therapies for a wide range of genetic diseases, and to potential treatments for some cystic fibrosis patients that may yield better outcomes than existing therapies.

23 Feb 2026

Gut microbiome may shape response to GLP-1 drugs, new review suggests

This review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy.

19 Feb 2026

New approach better predicts chemotherapy response in patients with triple-negative breast cancer

Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to better account for changes in gene expression within tumors relative to their unique microenvironments.

17 Feb 2026

AI tool could help identify life-threatening transplant complications

A powerful artificial intelligence (AI) tool could give clinicians a head start in identifying life-threatening complications after stem cell and bone marrow transplants, according to new research from MUSC Hollings Cancer Center.

16 Feb 2026

HER2 gastric cancer: Unraveling resistance at single-cell resolution

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies.

16 Feb 2026

Synergistic drug pair shows promise for spinal cord injury recovery

Spinal cord injury remains one of the most challenging neurological conditions to treat, largely because damage continues to worsen long after the initial trauma.

16 Feb 2026

Advances in pathogenesis and management of gastrointestinal motility disorders

Announcing a new publication for Acta Materia Medica journal. Gastrointestinal motility disorders (GIMDs) are characterized by impaired gastrointestinal motility.

13 Feb 2026

Blood omics data forecasts trauma outcomes with high accuracy

Researchers at the University of Colorado Anschutz have developed a way to predict how trauma patients will recover, days before complications come to fruition, by analyzing the molecules in their blood.

11 Feb 2026

Review links betel nut addiction to cancer, heart disease, and metabolic risks

This review examines the epidemiology, health risks, neurobiological mechanisms, and emerging treatments related to betel nut addiction worldwide. It highlights strong links with oral cancer, cardiometabolic disease, and addiction pathways while noting limited established therapies and the need for coordinated public health strategies.

11 Feb 2026

Polygenic analysis provides new insight into hypermobile Ehlers–Danlos syndrome

Hypermobile Ehlers–Danlos syndrome (hEDS) is one of the most common heritable connective tissue disorders.

10 Feb 2026

Type 2 diabetes and hypertension share a genetic link, study shows

Type 2 diabetes and high blood pressure share a genetic link, new research from the University of Surrey, UK and the Université de Lille, France shows.

10 Feb 2026