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Certain pre-existing conditions may highly increase a patient's risk of dying from COVID-19

A large, international study of COVID-19 patients confirmed that cardiovascular disease, hypertension, diabetes, congestive heart failure, chronic kidney disease, stroke and cancer can increase a patient's risk of dying from the virus.

8 Oct 2020

NIH clinical trial to test a combination treatment regimen for COVID-19

A clinical trial to test the safety, tolerability and efficacy of a combination treatment regimen for coronavirus disease 2019 (COVID-19) consisting of the antiviral remdesivir plus a highly concentrated solution of antibodies that neutralize SARS-CoV-2, the virus that causes COVID-19, has begun.

8 Oct 2020

Pre-existing conditions can increase patient's risk of dying from COVID-19

8 Oct 2020

SARS-CoV-2 infection analysis could help fight against COVID-19

Researchers in the United States has provided a detailed catalog of the interactions that occur between host cell proteins and RNA and the RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the course of infection.

7 Oct 2020

Research elucidates the molecular mechanism of lentiviral cross-species transmission

Humans are exposed continuously to the menace of viral diseases such as those caused by the Ebola virus, Zika virus and coronaviruses. Such emerging/re-emerging viral outbreaks can be triggered by cross-species viral transmission from wild animals to humans.

7 Oct 2020

Case report of arthritis in a COVID-19 patient

The current paper published in the The Lancet Rheumatology discusses arthritis in a 58-year-old white woman with COVID-19 of less than severe intensity.

7 Oct 2020

Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

Immune cells that can recognize residual HIV-infected cells in people living with HIV (PLWH) who take antiretroviral therapy (ART) remain active for years, says a new study published today in eLife.

7 Oct 2020

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

A new study published on the preprint server bioRxiv* aimed to investigate the impacts of COVID-19 on people with various illnesses. Specifically, the researchers at the Rockefeller Cancer Institute, and the University of Arkansas for Medical Sciences wanted to see the effects of COVID-19 on patients with cancer and other infectious diseases.

6 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

Study shows why antiretroviral therapy does not work in certain HIV patients

Increasingly, UPMC's chief of infectious diseases - a well-regarded expert in HIV/AIDS - is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus in check, but testing says otherwise.

6 Oct 2020

Development of a coarse-grained model of SARS-CoV-2 virion

A team of scientists of the University of Chicago and the University of California San Diego has developed a coarse-grained (CG) model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virion. The model can be used as a valuable resource to perform multiscale simulations of the SARS-CoV-2 virion. The study is currently available on the bioRxiv* preprint server.

5 Oct 2020

Study fails to establish independent risk factors for SARS-COV-2 infection in HIV patients

As the COVID-19 pandemic continues to spread worldwide, a new study published in the International Journal of Infectious Diseases in September 2020 reports that people with HIV infection are not at greater risk of COVID-19 compared to the general population.

5 Oct 2020

The implications of COVID-related sexual distancing and clinical service interruption

A recent study conducted in the Atlanta area reveals that coronavirus disease 2019 (COVID-19) related sexual distancing together with clinical service interruption for sexually transmitted diseases can potentially impact the future incidence of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). The study is currently available on the medRxiv* preprint server.

4 Oct 2020

Study reveals factors that increase risk of hospitalization and death in HIV patients diagnosed with COVID-19

Clinical trials are testing whether medications that treat human immunodeficiency virus (HIV) can also treat COVID-19, leading some patients with HIV to believe they might be protected against the coronavirus.

1 Oct 2020

A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

Discovery of high affinity binders for SARS-CoV-2 spike protein

An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.

30 Sep 2020

Methamphetamine use linked to risky sexual behavior

Recreational use of the illicit drug methamphetamine has long been associated with increases in overall impatient and risky behavior.

30 Sep 2020

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

Science's pursuits of unraveling how human cells fight viral infections kicked into high gear in 2020 with the devastating emergence of the SARS-CoV-2 virus.

30 Sep 2020

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

A new study by researchers at the Indian Institute of Science and the University of Queensland and published on the preprint server medRxiv in September 2020 discusses using a novel tool to identify the most effective among currently known anti-SARS-CoV-2 NAbs.

29 Sep 2020

Case fatality rates for COVID-19 and health indicators

Researchers from Turkey and Switzerland collaborated to study the nation-specific case fatality rates for COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The pandemic has affected around 33.5 million people worldwide and killed over 1 million making it one of the largest global health crises in recent memory.

29 Sep 2020

HIV News and Research

Certain pre-existing conditions may highly increase a patient's risk of dying from COVID-19

NIH clinical trial to test a combination treatment regimen for COVID-19

Pre-existing conditions can increase patient's risk of dying from COVID-19

SARS-CoV-2 infection analysis could help fight against COVID-19

Research elucidates the molecular mechanism of lentiviral cross-species transmission

Case report of arthritis in a COVID-19 patient

Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

SARS-CoV-2 and anti-COVID-19 drugs activate Kaposi sarcoma-associated herpesvirus

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Study shows why antiretroviral therapy does not work in certain HIV patients

Development of a coarse-grained model of SARS-CoV-2 virion

Study fails to establish independent risk factors for SARS-COV-2 infection in HIV patients

The implications of COVID-related sexual distancing and clinical service interruption

Study reveals factors that increase risk of hospitalization and death in HIV patients diagnosed with COVID-19

A detailed map of latent virus reservoir in individuals with HIV

Discovery of high affinity binders for SARS-CoV-2 spike protein

Methamphetamine use linked to risky sexual behavior

Study shows how human cells fight viral infections with the emergence of SARS-CoV-2

New graphical tool to identify potent neutralizing antibodies against SARS-CoV-2

Case fatality rates for COVID-19 and health indicators

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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