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Ancient genetic mixing shaped the evolution of modern humans

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe.

18 Mar 2025

Can yogurt and kefir help prevent osteoporosis? Scientists examine the facts

Fermented dairy products and probiotics may support bone health by enhancing calcium absorption, modulating inflammation, and influencing bone remodeling, though human studies show mixed results.

18 Mar 2025

Identifying genetic resistance factors and antimicrobial resistance phenotypes in MRSA strains

With the rising prevalence of methicillin-resistant Staphylococcus (S.) aureus (MRSA), a multi drug resistant strain, treatment has become a challenge.

18 Mar 2025

NKD2 protein discovery opens up new possibilities in the fight against bone loss

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Mar 2025

Understanding how JAK inhibitors may increase blood clot risk

Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?

17 Mar 2025

IL-12 targeting could open pathways for new Alzheimer's treatments

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

17 Mar 2025

Researchers move closer to a functional cure for chronic hepatitis B

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

17 Mar 2025

New research reveals potential path forward for glioblastoma treatment

Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy.

17 Mar 2025

Researchers discover MAFB and CEBPA’s role in hypospadias pathogenesis

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

17 Mar 2025

Congenital heart defects may be linked to increased cancer risk in babies and mothers

Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Association's flagship journal Circulation.

17 Mar 2025

Baylor study sheds light on role of CDKL1 and CDKL2 in neurodevelopmental disorders

CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with seizures.

14 Mar 2025

Novel cyclic peptide antagonist can be a promising therapeutic approach for MASH

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

14 Mar 2025

Study unveils mechanisms behind antigenic variation in pathogens

A new study by LMU and Helmholtz Munich shows how pathogens control changes in their cell surface to evade the immune system.

14 Mar 2025

Current state and future prospects of artificial ligaments for treating ACL injuries

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

14 Mar 2025

Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2025