Lungs News and Research

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3D-printed tracheal replacement splint offers hope for treating rare developmental abnormality

Ramiah Martin isn't like other little girls, and that's perfectly fine with her mother. "She is nothing short of a miracle," Leanne Martin said of her daughter, who was facing long odds before her birth in December 2017, after being diagnosed with heart problems during a prenatal ultrasound.

21 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

A new study demonstrates significantly altered structure and cellularity of Peyer’s patches in deceased COVID-19 patients.

21 Dec 2021

Do reactive oxygen species play a role in fighting COVID-19?

Serum-free thiols are known to reflect the activity of reactive oxygen species in the body, and researchers have been examining the difference in these thiols in COVID-19 patients.

21 Dec 2021

Measuring airway inflammation when diagnosing and treating asthma patients

In this interview, Carol Stonham, the head of a Locality Based FeNO referral service, talks to NewsMed about measuring airway inflammation when diagnosing and treating asthma patients.

From Bedfont® Scientific Ltd 21 Dec 2021

Risk of hospitalization for infants and children with COVID-19 below 1%

Children are a low-risk group for COVID-19 following infection with SARS-CoV-2, with less than 2% of European hospitalizations with the disease being in children below the age of 19.

21 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

A new study posted to the bioRxiv* preprint server aimed to demonstrate whether the loss of the QTQTN motif attenuates SARS-CoV-2 replication in respiratory cells in vitro and pathogenesis in hamsters.

20 Dec 2021

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

The Omicron variant of SARS-CoV-2 may be significantly better than previous variants at evading vaccine-induced antibodies, according to new research from Cambridge - but preliminary evidence suggests it is less likely to cause severe COVID-19 illness in the lungs.

20 Dec 2021

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Researchers study influenza and SARS-CoV-2 infection models to identify lung memory B cells during viral infection.

20 Dec 2021

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

A new study explored whether wearing masks either increased, reduced, or did not alter various respiratory variables.

20 Dec 2021

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Race-based formula used to diagnose lung disease should be changed, study suggests

New results from a long-term epidemiologic study reveal that one of the oldest racially based diagnostic formulas in medicine is no better than a race-neutral equation, which suggests the formula used to diagnose lung disease should be changed.

16 Dec 2021

Nanoparticle therapeutic can be a potential new approach for treating malignant pleural effusion

Researchers at Wake Forest School of Medicine have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE).

16 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

Study: Pregnant women with disabilities have increased risk for birth complications and death

Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health.

15 Dec 2021

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers demonstrate that the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 require endogenous IFITM2 expression for efficient replication.

15 Dec 2021

Researchers spot signs of 'pre-resistance' in bacteria for the first time

Scientists have spotted signs of 'pre-resistance' in bacteria for the first time – signs that particular bacteria are likely to become resistant to antibiotics in the future – in a new study led by UCL and Great Ormond Street Hospital researchers.

15 Dec 2021

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

High pressure (hyperbaric) oxygen resolves severe breathing difficulties in COVID-19 patients much more quickly than standard therapy, taking an average of 3 rather than 9 days, reveal the results of a small comparative clinical trial published online in Emergency Medicine Journal.

15 Dec 2021

Lungs News and Research

3D-printed tracheal replacement splint offers hope for treating rare developmental abnormality

Molecular mechanism of SARS-Cov-2-induced thrombosis

Severe COVID-19 found to be associated with disrupted intestinal Peyer’s patches

Do reactive oxygen species play a role in fighting COVID-19?

Measuring airway inflammation when diagnosing and treating asthma patients

Risk of hospitalization for infants and children with COVID-19 below 1%

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

QTQTN motif upstream of furin-cleavage site in SARS-CoV-2 infection and pathogenesis

New Omicron variant may be better at evading vaccine-induced antibodies, research shows

Lung memory B-cells provide primary protection against SARS-CoV-2 reinfection

Cloth facemasks worn during exercise are unlikely to cause significant respiratory changes

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Race-based formula used to diagnose lung disease should be changed, study suggests

Nanoparticle therapeutic can be a potential new approach for treating malignant pleural effusion

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Experimental and computational synergy considered a promising approach in COVID-19 patients

Study: Pregnant women with disabilities have increased risk for birth complications and death

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers spot signs of 'pre-resistance' in bacteria for the first time

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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