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Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Researchers at the University of São Paulo (USP) in Brazil have identified a new class of molecules capable of stopping the excessive inflammation typical of the severe form of COVID-19 without impairing the immune response to SARS-CoV-2, the virus that causes the disease.

25 Jul 2023

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Researchers describe the findings of the COVID-19 Citizen Science Study.

25 Jul 2023

Researchers uncover the biology behind insulin production

The discovery of insulin has saved the lives of millions of people with diabetes worldwide, but little is known about the first step of insulin synthesis.

25 Jul 2023

Using 'click chemistry' to create novel multi-protein anti-cancer agents

A potent anti-cancer therapy has been created using Nobel prize-winning "click chemistry", where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

24 Jul 2023

Lactate plays a critical role in helping neural stem cells develop into specialized neurons

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

24 Jul 2023

Arming phages with heterologous effectors paves the way for successful UTI treatment

Study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes.

24 Jul 2023

Researchers uncover novel targets for treatment of schistosomiasis

The worms that cause schistosomiasis (Schistosoma mansoni) are unusual in several ways, especially the fact that male and female adults must stay paired together throughout their lives for reproduction to be successful.

21 Jul 2023

Customizing carbon nanotube biosensors to detect bacteria and viruses

The new sensor design resembles a molecular toolbox that can be used to quickly assemble sensors for a variety of purposes.

21 Jul 2023

Salk researchers uncover molecular mechanisms of HIV drug resistance

Salk Institute researchers, in collaboration with the National Institutes of Health, have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV.

21 Jul 2023

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Drawing inspiration from natural sensory systems, an MIT-led team has designed a novel sensor that could detect the same molecules that naturally occurring cell receptors can identify.

21 Jul 2023

Probiotic combination could reduce incidence of toxic shock syndrome

The widespread, pathogenic microbe Staphylococcus aureus can colonize the skin and mucous membranes throughout the body, particularly the vagina and gastrointestinal tract.

21 Jul 2023

Researchers discover NFIC molecule that may prevent pancreatic cancer

The pancreas, located behind the stomach, manages the energy supply in our body. It does so by secreting proteins (enzymes) responsible for glucose – the body's main fuel – reaching other organs when required and in the right amount.

21 Jul 2023

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT).

21 Jul 2023

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

A group of authors summarized adjuvant mechanisms, characteristics, and applications, seeking to overcome current vaccine limitations.

21 Jul 2023

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Researchers examine plasma interleukin-6, vascular cell adhesion molecule-1, and C-reactive protein levels in pregnant women with preeclampsia.

20 Jul 2023

Study shows how NSAIDs exacerbate C. difficile infections

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide?

19 Jul 2023

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Arrayjet, a leading provider of inkjet liquid-handling solutions, today announced that it has partnered with Chemspace, the largest online catalogue of small molecules and biologics, to augment and streamline the Company’s small molecule microarray (SMM) service offering.

From Arrayjet Ltd 19 Jul 2023

New kidney tissue atlas could advance understanding of kidney injury and disease

Researchers at Washington University School of Medicine in St. Louis helped lead a major study, funded by the National Institutes of Health (NIH), that uncovered rich cellular and molecular diversity in healthy and diseased kidneys, creating a kidney tissue atlas that will help further understanding of kidney injury and disease.

19 Jul 2023

Study provides new insights into the mechanism of Dmc1 filament assembly

Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction.

19 Jul 2023

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

The discovery of antibiotics in 1928 was a major turning point in the history of medicine. For the first time since the dawn of human civilization, doctors had gained access to an extremely powerful and effective tool to fight against a wide variety of bacterial infections.

19 Jul 2023

Molecule News and Research

Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Unlocking the secrets of asymptomatic COVID-19 infections: HLA-B*15:01 connection revealed

Researchers uncover the biology behind insulin production

Using 'click chemistry' to create novel multi-protein anti-cancer agents

Lactate plays a critical role in helping neural stem cells develop into specialized neurons

Arming phages with heterologous effectors paves the way for successful UTI treatment

Researchers uncover novel targets for treatment of schistosomiasis

Customizing carbon nanotube biosensors to detect bacteria and viruses

Salk researchers uncover molecular mechanisms of HIV drug resistance

New sensor may be deployed to screen patients for hard-to-diagnose cancers

Probiotic combination could reduce incidence of toxic shock syndrome

Researchers discover NFIC molecule that may prevent pancreatic cancer

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Advancing vaccine adjuvants: exploring cutting-edge platforms for improved immunization

Pro-inflammatory cytokine levels and their relation to preeclampsia severity

Study shows how NSAIDs exacerbate C. difficile infections

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

New kidney tissue atlas could advance understanding of kidney injury and disease

Study provides new insights into the mechanism of Dmc1 filament assembly

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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