Proliferation News and Research

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International study identifies new drug target for treating glioblastoma

A new international study co-led by Cleveland Clinic has identified a new drug target for treating glioblastoma. This target is part of a never-before defined cellular pathway found to contribute to the spread and proliferation of a dangerous subset of cancer cells, called glioma stem cells.

22 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

Researchers seek to understand the regenerative potential of newborn mammalian hearts

Unlike lower vertebrates, mammals are unable to repair their adult hearts after injuries that include heart attacks. This inability in humans leads to heart failure -- a deadly and costly disease that affects more than 5 million Americans.

10 Aug 2019

Study reveals Lassa virus' soft spot

As this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa.

9 Aug 2019

Thymol antimicrobial in corn starch can help fight mosquito-borne diseases

The Aedes aegypti mosquito is the major vector for many urban arboviruses, which can cause serious conditions such as dengue fever, Zika virus, Chikungunya, and yellow fever. Now, researchers have developed a cheap but effective larvicide using cornstarch.

7 Aug 2019

Researchers open up possible avenue for new cancer treatments without side effects

Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports proliferation and survival of tumor cells.

6 Aug 2019

International collaborative pinpoints key areas to catalyze nutrition-based cancer prevention

An international collaborative led by Ludwig Cancer Research and Cancer Research UK has identified key areas that are central to uncovering the complex relationship between nutrition and cancer.

31 Jul 2019

New device traps and analyzes single cells for faster HPV-related cervical cancer screening

Several screening tests for cervical cancer have been developed in recent years. One technique uses immunofluorescent staining to determine the levels of biomarkers to indicate a cell is undergoing HPV-related cancerous growth.

31 Jul 2019

Herbal medicine for preventing, healing vascular diseases

The system connects the arteries to the veins. There are 100,000 miles of blood vessels in the adult human body.

30 Jul 2019

Mechanical forces regulate cellular behavior during embryonic development of the brain

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons.

29 Jul 2019

Study finds specific direct targets for lung cancer treatment

A team of researchers at the Salk Institute has found two therapeutic targets for the deadly type of lung cancer, non-small-cell lung carcinomas (NSCLCs), which accounts for 85 percent of all lung cancer cases. They believe that the breakthrough discovery could pave the way for the development of new treatments for a majority of lung cancer patients.

29 Jul 2019

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Australian researchers have unlocked the mystery as to why the chemotherapy drug 5-Fluorouracil is not effective at treating certain cancers.

17 Jul 2019

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research.

17 Jul 2019

Evaluating safety and efficacy of magnetically labeled mesenchymal stem cells

Cells equipped with superparamagnetic iron oxide nanoparticles can be directed to a specific location by an external magnetic field, which is beneficial for tissue repair.

16 Jul 2019

Alternate cell growth pathway could open door to new treatments for metastatic cancers

While researchers have a basic understanding of how primary cancer cells grow, less is known about metastasis, the deadly process by which cancers spread.

12 Jul 2019

UGR scientists design new hydrogel that aids in cartilage regeneration

Cartilage degeneration and damage treatment remain a major challenge in today's society; hence, tissue engineering strategies are being developed to investigate new alternatives based on a combination of cell therapy and 3D scaffolds to support cartilage cells

10 Jul 2019

Researchers pinpoint treatment target for rare liver cancer in adolescents, young adults

New findings show how a genetically aberrant, fused protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the enzymes that it recruits.