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Researchers show a simple way to protect transplanted islets from rejection

Type 1 diabetes, or T1D, results from the autoimmune destruction of the insulin-producing cells of the pancreas. People with T1D require exogenous insulin and suffer swings in the levels of glucose in the blood that impact life expectancy and increase risks of cardiovascular disease, neuropathies and kidney failure.

22 Oct 2020

Distinct DNA methylation signature found in the cord blood of newborns diagnosed with ASD

A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD).

22 Oct 2020

Researchers develop portable device to quantify capsaicin content in chili peppers

Some people love spicy food -- the hotter, the better. Others go out of their way to avoid the palate-singeing burn of capsaicin, the compound that gives chili peppers their kick.

22 Oct 2020

Dietary supplement represents an innovative strategy to help in the fight against SARS-CoV-2

SPIN (SPermidin and eugenol INtegrator for contrasting incidence of coronavirus in EU population) is a European project powered by EIT Food that is currently developing a dietary supplement supporting the function of the immune system in the fight against SARS-CoV-2 infections in population at high risk.

21 Oct 2020

UCLA researchers discover compound that stimulates muscle cells in mice

UCLA researchers have identified a compound that can reproduce the effect of exercise in muscle cells in mice. The findings are published in the journal Cell Reports Medicine.

21 Oct 2020

High flavanol diet associated with lower blood pressure

People who consume a diet including flavanol-rich foods and drinks, including tea, apples and berries, could lead to lower blood pressure, according to the first study using objective measures of thousands of UK residents' diet.

21 Oct 2020

Novel multimodal intervention improves physical fitness and cognitive function

Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids.

19 Oct 2020

CBD could reduce lung damage caused by COVID-19

One way CBD appears to reduce the "cytokine storm" that damages the lungs and kills many patients with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is known to reduce inflammation and whose levels are dramatically reduced in the face of this storm.

19 Oct 2020

Antispastic drug candidate could offer new hope for millions of patients suffering from spasticity

First-in-class antispastic drug candidate to reach clinical phase is published in the prestigious life science journal, Cell. Drug candidate MPH-220 could mean new hope for millions of patients suffering from spasticity.

16 Oct 2020

Dotmatics introduces a self-service, scientific visualization and analytics application for small molecule discovery

Dotmatics Ltd, a scientific informatics software and services company that is driving the automation of laboratory data workflows for scientific discovery and innovation research, today announced it has expanded its product portfolio to include Blueprint, a self-service, scientific visualization and analytics application for small molecule discovery.

From Dotmatics 15 Oct 2020

Researchers are developing a new class of compounds against various cancers

Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and lymphoma.

14 Oct 2020

Axol Bioscience introduces multi-electrode array screening services for human iPSC-derived cells

Axol Bioscience today announced the expansion of its services, with the introduction of array screening for human induced pluripotent stem cells.

From Axol Bioscience Ltd 13 Oct 2020

Female mosquitoes can detect a combination of four different substances in blood

Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

A new study published on the preprint server bioRxiv in October 2020 shows that a combination of a new compound GNS561 and remdesivir act synergistically against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This suggests that autophagy inhibitors could be an alternative strategy for SARS-CoV-2 infection.

12 Oct 2020

Suramin shows promise as COVID-19 treatment

A new study published on the preprint server bioRxiv reports the elucidation of the mechanism of inhibition of SARS-CoV-2 by a non-nucleotide inhibitor called suramin. This is the first such compound to be shown to have such activity and shows promise for use as a repurposed drug against COVID-19.

12 Oct 2020

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

Researchers develop mitochondrial-targeted prodrug for treating glioblastoma

Houston Methodist researchers found that mice harboring human glioblastoma tumors in their brains had greatly enhanced survival and weight gain when given a newly developed prodrug.

9 Oct 2020

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene.

8 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.

7 Oct 2020

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

7 Oct 2020

Compound News and Research

Researchers show a simple way to protect transplanted islets from rejection

Distinct DNA methylation signature found in the cord blood of newborns diagnosed with ASD

Researchers develop portable device to quantify capsaicin content in chili peppers

Dietary supplement represents an innovative strategy to help in the fight against SARS-CoV-2

UCLA researchers discover compound that stimulates muscle cells in mice

High flavanol diet associated with lower blood pressure

Novel multimodal intervention improves physical fitness and cognitive function

CBD could reduce lung damage caused by COVID-19

Antispastic drug candidate could offer new hope for millions of patients suffering from spasticity

Dotmatics introduces a self-service, scientific visualization and analytics application for small molecule discovery

Researchers are developing a new class of compounds against various cancers

Axol Bioscience introduces multi-electrode array screening services for human iPSC-derived cells

Female mosquitoes can detect a combination of four different substances in blood

Genoscience Pharma's GNS561 shows potential against SARS-CoV-2 in vitro

Suramin shows promise as COVID-19 treatment

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

Researchers develop mitochondrial-targeted prodrug for treating glioblastoma

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

Endocannabinoids in the body can help fight intestinal infections

Study may explain why cannabis plant can reduce symptoms of various bowel conditions

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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