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Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

In a new study, a team of researchers assessed the neutralizing activity of XAV-19, a glyco-humanized polyclonal antibody derived from hyperimmunized animal hosts, against the SARS-CoV-2 Omicron variant.

1 Feb 2022

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

In a new study, researchers designed artificial intelligence (AI)-based primers for the SARS-CoV-2 Omicron variant.

1 Feb 2022

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

In a new study, a team of researchers used cryo-electron microscopy to determine the spike (S) structures of the SARS-CoV-2 Omicron variant to understand how the mutations that alter its primary sequence impact S conformation.

1 Feb 2022

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

31 Jan 2022

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Researchers from Moderna, the developers of one key vaccine, have been investigating its ability to protect against the Omicron variant.

31 Jan 2022

New study on mutation origination fundamentally challenges neo-Darwinism

A new study by a team of researchers from Israel and Ghana has brought the first evidence of nonrandom mutation in human genes, challenging a core assumption at the heart of evolutionary theory by showing a long-term directional mutational response to environmental pressure.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Study finds how a change in cell environment triggers autism with genetic vulnerability

People with autism spectrum disorders all have characteristic behavioral difficulties. Nevertheless, the important heterogeneity of their symptoms remains one of the major questions for scientists and physicians.

31 Jan 2022

A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

A team of scientists from the United States has recently defined the substrate envelop of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The study is currently available on the bioRxiv* preprint server while awaiting peer review.

31 Jan 2022

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Researchers have been investigating the phosphorylation of the nucleocapsid protein.

27 Jan 2022

Mutation News and Research

Mutational analysis of SARS-CoV-2 main protease

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

Impact of using AI to generate primers for detection of SARS-CoV-2 Omicron variant

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

New study on mutation origination fundamentally challenges neo-Darwinism

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Researchers identify genetic cause of rare interstitial lung disease in a young child

Study finds how a change in cell environment triggers autism with genetic vulnerability

A substrate envelope approach to examine drug resistance potential of SARS-CoV-2 Mpro

Scientists evaluate zoonotic potential of NeoCoV, a coronavirus related to MERS-CoV

Study reveals link between muscular dystrophy and sphingolipids

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

New approach using RNA therapeutic can fix protein problems in cystic fibrosis

SARS-CoV-2 mutations and their impact on spike protein-specific T lymphocytes

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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