Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study reveals a mechanism linking DDT exposure to Alzheimer's disease

A new study led by researchers from Florida International University (FIU) reveals a mechanism linking the pesticide DDT to Alzheimer's disease.

17 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

A new method for imaging the placenta in pregnant patients

A study published in Nature Biomedical Engineering details a novel method for imaging the placenta in pregnant patients as well as the results of a pilot clinical study.

16 Aug 2022

CSU part of $12.5 million-supported institute to advance virus research and education

Colorado State University researchers are part of a $12.5 million National Science Foundation-supported institute that will advance research and education around viral emergence – the process of viruses jumping from animals to humans.

16 Aug 2022

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

One woman is diagnosed with breast cancer every fourteen seconds somewhere across the globe - based on data showing that an approximate 2.3 million women worldwide were newly diagnosed with breast cancer in 2020.

16 Aug 2022

Deep learning model can accurately show the presence and location of cancer in pathological images

A research team led by Professor Park Sang-Hyun of the Department of Robotics and Mechatronics Engineering (also in charge of the Artificial Intelligence major) at DGIST (President Kuk Yang) developed a weakly supervised deep learning model that can accurately show the presence and location of cancer in pathological images based only on data where the cancer is present. Existing deep learning models needed to construct a dataset, in which the location of the cancer was accurately drawn, to specify the cancer site.

12 Aug 2022

Portable diagnostic device deployed in sub-Saharan Africa to identify cases of Kaposi sarcoma

A portable diagnostic device designed by researchers at Cornell Engineering and Weill Cornell Medicine has been deployed in clinical tests in Uganda to identify cases of Kaposi sarcoma, a common yet difficult-to-detect cancer that often signals the presence of HIV infection.

11 Aug 2022

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Researchers explored the immunogenicity of a replicon ribonucleic acid (repRNA) COVID-19 vaccine, repRNA-CoV2S, in pigtail macaques.

11 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Understanding the emotions behind memories

In this interview, we speak to Professor Kay Tye about her latest research into memories and how we can start to understand the emotions behind them.

10 Aug 2022

Novel class of drug regresses active brain metastases in breast cancer patients

An Austrian study led by MedUni Vienna showed that active brain metastases in breast cancer patients are partially or even completely regressed by a novel class of drug. This is a chemical conjugate of an antibody and a chemotherapy drug that, according to current findings, opens up a completely new avenue in oncological research and targeted therapy.

10 Aug 2022

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Recently, 'Long COVID' is becoming a significant issue worldwide. It refers to a variety of symptoms that persist over an extended period after the patient has recovered from a novel coronavirus infection (COVID-19). In many cases, it is unclear what causes Long COVID symptoms, and there is insufficient information regarding recovery time.

10 Aug 2022

Next-generation sequencing system yields results comparable to traditional diagnostics

In the pursuit of accurate diagnoses for illnesses, doctors have traditionally used multiple methods — including culturing patient samples on a wide variety of media, reviewing countless medical records and analyzing clinical data using complex mathematical algorithms — to try to identify the bacterium, virus, fungus or other pathogen responsible for an infection.

10 Aug 2022

Maternal personality disorder symptoms associated with insecure attachment in adolescent offspring

It should come as no great surprise that mothers have profound influence on their children. But what about mothers who have their own personality disorder symptoms, such as problems getting along with others? New research finds, for the first time, that maternal personality disorder symptoms impact their adolescent children who subsequently show a higher likelihood of insecure attachment.

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Researchers examined the impact of tau neuropathology of APOE3 Christchurch (APOE3ch) homozygote against Alzheimer’s disease.

8 Aug 2022

Pathology News and Research

Further Reading

Study reveals a mechanism linking DDT exposure to Alzheimer's disease

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

A new method for imaging the placenta in pregnant patients

CSU part of $12.5 million-supported institute to advance virus research and education

Non-invasive biomarker could aid with earlier diagnosis of breast cancer metastasis

Deep learning model can accurately show the presence and location of cancer in pathological images

Portable diagnostic device deployed in sub-Saharan Africa to identify cases of Kaposi sarcoma

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Novel model reveals how genomic instability arises in histologically benign tissue

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Understanding the emotions behind memories

Novel class of drug regresses active brain metastases in breast cancer patients

Researchers collaborate on a 15-month case study to analyze patient’s recovery from impaired adrenocorticotropic hormone

Next-generation sequencing system yields results comparable to traditional diagnostics

Maternal personality disorder symptoms associated with insecure attachment in adolescent offspring

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

New insights into the understanding of how ApoE variants contribute to Tau pathology in Alzheimer’s disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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