Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Healthy lifestyle may reduce the risk of dementia and extend life expectancy

A US study published by The BMJ today suggests that a healthy lifestyle is associated with a longer life expectancy among both men and women, and they lived a larger proportion of their remaining years without Alzheimer's disease.

14 Apr 2022

Exercise maintains insulin and body mass index levels to help protect brain volume

Studies have shown that exercise helps protect brain cells. A new study looking at the mechanisms involved in this relationship suggests that the role exercise plays in maintaining insulin and body mass index levels may help protect brain volume and thus help stave off dementia.

14 Apr 2022

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

On Thursday, April 7, the Centers for Medicare and Medicaid (CMS) formalized its plan to cover the anti-amyloid drug Aduhelm only for patients enrolled in clinical trials.

8 Apr 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Researchers develop new method to ‘time jump’ skin cells by 30 years

Research from the Babraham Institute has developed a method to 'time jump' human skin cells by 30 years, turning back the aging clock for cells without losing their specialized function.

8 Apr 2022

Mutant mice with a human gene variant exhibits ADHD-like problems

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD).

7 Apr 2022

Nobel-prize-winning breakthrough: Discovery of ion-channel sensors for temperature and pressure

For centuries, understanding the basis for how we detect, process and react to light, sound, temperature, pressure and other environmental signals has been a scientific focus.

7 Apr 2022

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).

6 Apr 2022

Researchers discover over 40 new genetic markers for Alzheimer’s disease

A new Nature Genetics study describes over 70 gene markers that appear to be significantly associated with AD risk using translational genomics.

6 Apr 2022

People with some types of epilepsy may have a lower quality of life, study suggests

A new study suggests that people with epilepsy associated with head injuries, especially the type not well controlled by medication, are more likely to have other health conditions like depression, post-traumatic stress disorder (PTSD), back pain and headache that may result in them reporting a lower quality of life.

6 Apr 2022

Combining two biomarkers could help identify patients with subcortical small-vessel disease

In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.

5 Apr 2022

Study lays the groundwork for development of new treatments for Alzheimer's

It's long been known that brain vessel dysfunction induced by a peptide called amyloid-beta (Aβ) could lead to Alzheimer's disease (AD).

2 Apr 2022

Investigational new drug may be safe for patients with mild cognitive impairment, dementia

A small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Alzheimer's disease suggests it is safe and may be associated with improvements in executive function, thinking and memory skills.

31 Mar 2022

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

31 Mar 2022

New project launched to explore how GI microbiota may contribute to neurodegeneration

Alzheimer's disease (AD) is a type of dementia that affects memory, thinking and behavior. According to the Alzheimer's Association, an estimated 6.2 million Americans are living with this progressive neurologic disorder, and it is the sixth-leading cause of death in the U.S.

31 Mar 2022

Puerto Rican people with diabetes and high blood pressure show greater brain structural disruptions

The high rate of diabetes and high blood pressure combined in Puerto Rican people may be linked to structural changes in the brain, according to a study published in the March 30, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

31 Mar 2022

Common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner

Experts at Indiana University School of Medicine have helped identify that a common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner without a connection to disease.

29 Mar 2022

Rutgers researchers use roundworms to unravel how cells communicate with one another

Scientists have long puzzled about a critical way that cells communicate with one another, but Rutgers researchers have used a simple roundworm to solve the mystery.

25 Mar 2022

Physical activity boosts cognitive performance in middle-aged and older adults, study shows

A new study by researchers at The University of California San Diego School of Medicine adds to the canon of research associating physical activity with cognitive performance, this time using 90 middle-aged and older participants who wore accelerometers while physically active and completed mobile cognitive testing from home.

24 Mar 2022

Alzheimer's Disease News and Research

Further Reading

Healthy lifestyle may reduce the risk of dementia and extend life expectancy

Exercise maintains insulin and body mass index levels to help protect brain volume

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

Researchers develop new method to ‘time jump’ skin cells by 30 years

Mutant mice with a human gene variant exhibits ADHD-like problems

Nobel-prize-winning breakthrough: Discovery of ion-channel sensors for temperature and pressure

Severe COVID linked to RAAS and hyperlipidemia associated metabolic syndrome conditions

Researchers discover over 40 new genetic markers for Alzheimer’s disease

People with some types of epilepsy may have a lower quality of life, study suggests

Combining two biomarkers could help identify patients with subcortical small-vessel disease

Study lays the groundwork for development of new treatments for Alzheimer's

Investigational new drug may be safe for patients with mild cognitive impairment, dementia

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

New project launched to explore how GI microbiota may contribute to neurodegeneration

Puerto Rican people with diabetes and high blood pressure show greater brain structural disruptions

Common protein found in neurodegenerative diseases forms amyloid filaments in an age-dependent manner

Rutgers researchers use roundworms to unravel how cells communicate with one another

Physical activity boosts cognitive performance in middle-aged and older adults, study shows

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