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Study finds promising new approach to treating locally advanced pancreatic cancer

A new Phase Ib/II study from researchers at The University of Texas MD Anderson Cancer Center and Moffitt Cancer Center found that combining sensitizing drugs with a specific form of radiation therapy may be more effective in patients with locally advanced pancreatic cancer, yielding a higher progression-free survival (PFS) and overall response rate (ORR).

28 Nov 2023

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

A study by Brigham investigators revealed how genetic changes in certain types of brain cells may contribute to the inflammatory response seen in Alzheimer's disease.

28 Nov 2023

Salk scientists uncover mechanism for repairing damaged nerves during peripheral neuropathy

Each year in the United States there are more than 3 million cases of peripheral neuropathy, wherein nerves outside of the brain and spinal cord are damaged and cause pain and loss of feeling in the affected areas.

28 Nov 2023

Researchers discover new gene targets for precision oncology in esophageal cancer

Researchers have identified a new way to screen genes that cause several different types of cancers to grow, identifying particularly promising targets for precision oncology in oral and esophageal squamous cancers.

28 Nov 2023

FDA awards grant for phase 1 clinical trial of experimental AML/MDS treatment

Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) - two related blood diseases that disproportionally strike older adults - are notoriously difficult to treat and associated with high relapse rates.

28 Nov 2023

Researchers develop $1 cancer treatment using engineered bacteria

What if a single one-dollar dose could cure cancer?

27 Nov 2023

SECRE technique paves way for new therapeutics for autoimmune diseases

Scientists have developed a potentially transformative new technique that could aid in the discovery and development of new therapeutics for a number of globally prevalent autoimmune diseases.

27 Nov 2023

Researchers identify potential new drug target for treating Barth syndrome

In a Nature Metabolism paper published today, researchers from the University of Pittsburgh detail a potential new target and a small-molecule drug candidate for treating Barth syndrome, a rare, life-threatening and currently incurable genetic disease with devastating consequences.

23 Nov 2023

AmoyDx and CST Expand Existing Partnership for the Development of Companion Diagnostics (CDx) to Support Precision Oncology

Cell Signaling Technology (CST), a life science biotechnology company and leading provider of antibodies, kits, and services, and Amoy Diagnostics Co., Ltd. (AmoyDx), a China-based innovative molecular diagnostics company in the field of precision oncology, announced today the expansion of their ongoing partnership for companion diagnostic (CDx) development in China.

From Cell Signaling Technology 23 Nov 2023

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

In Alzheimer's disease and related dementias, cognitive decline is driven by the overaccumulation of a normal brain protein known as tau.

22 Nov 2023

Repurposed drugs hold promise for targeting cancer stem cells

In a review published in the journal Genes & Diseases, researchers from ICMR-National Institute of Nutrition (NIN), advocate for the repurposing of non-cancer drugs to target these elusive CSCs.

22 Nov 2023

Researchers discover way to reverse brain aging caused by COVID-19

University of Queensland researchers have found a way to reverse a cellular process triggered by COVID-19 that contributes to premature aging of the brain.

22 Nov 2023

MaxCyte joins the alliance for mRNA medicines (AMM) as a founding member

MaxCyte, Inc. today announced that it has joined the Alliance for mRNA Medicines, as a founding member.

From MaxCyte, Inc. 22 Nov 2023

Scientists unravel iron-based memory mechanism in bacteria

Scientists have discovered that bacteria can create something like memories about when to form strategies that can cause dangerous infections in people, such as resistance to antibiotics and bacterial swarms when millions of bacteria come together on a single surface.

21 Nov 2023

Novel urine-based prognostic model promises to transform bladder cancer treatment

In a study published in the journal Genes & Diseases, researchers from Fudan University, have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.

21 Nov 2023

AI and synthetic patients could make early diagnosis of chronic fatigue syndrome more feasible

Between 17 and 24 million people worldwide suffer from chronic fatigue syndrome, a deeply debilitating and difficult-to-diagnose condition.

21 Nov 2023

Researchers discover new option to target the metastatic capacity of melanoma cells

As an extremely aggressive form of skin cancer, cutaneous melanoma is still associated with a high mortality rate. Enormous progress has recently been made in the fight against deadly metastasis, but existing therapeutic measures are still not effective in many cases.

21 Nov 2023

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

Ghent University and the booming Ghent biotech landscape welcome a brand new spin-off: Amalus Therapeutics is developing a new class of drugs that selectively target corrupt fibroblast cells.

20 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Almirall S.A., a global biopharmaceutical company focused on medical dermatology, and Absci Corporation, a generative AI drug creation company, today announced a drug discovery partnership aimed to develop and commercialize AI-designed therapeutics to fight chronic and debilitating dermatological diseases. The partnership combines Absci’s Integrated Drug Creation™ platform with Almirall’s dermatological expertise with the goal of delivering life-changing medicines to patients, marking another step forward in AI drug creation.

20 Nov 2023

Therapeutics News and Research

Study finds promising new approach to treating locally advanced pancreatic cancer

Study uncovers mechanisms underlying microglia-driven neuroinflammation in Alzheimer's disease

Salk scientists uncover mechanism for repairing damaged nerves during peripheral neuropathy

Researchers discover new gene targets for precision oncology in esophageal cancer

FDA awards grant for phase 1 clinical trial of experimental AML/MDS treatment

Researchers develop $1 cancer treatment using engineered bacteria

SECRE technique paves way for new therapeutics for autoimmune diseases

Researchers identify potential new drug target for treating Barth syndrome

AmoyDx and CST Expand Existing Partnership for the Development of Companion Diagnostics (CDx) to Support Precision Oncology

Reducing cholesterol esters protects the brain against Alzheimer's-like damage

Repurposed drugs hold promise for targeting cancer stem cells

Researchers discover way to reverse brain aging caused by COVID-19

MaxCyte joins the alliance for mRNA medicines (AMM) as a founding member

Scientists unravel iron-based memory mechanism in bacteria

Novel urine-based prognostic model promises to transform bladder cancer treatment

AI and synthetic patients could make early diagnosis of chronic fatigue syndrome more feasible

Researchers discover new option to target the metastatic capacity of melanoma cells

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Almirall and Absci partner to develop AI-designed therapeutics for dermatological diseases

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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