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Alcohol consumption may increase risk for breast cancer

A University of Houston researcher and his team have discovered an important link between alcohol and breast cancer by identifying a cancer-causing gene triggered by alcohol

15 Mar 2016

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

New research from Boston Children's Hospital could potentially change how doctors approach two blinding diseases: 'Wet' age-related macular degeneration (AMD), the leading cause of blindness in the elderly, and macular telangiectasia (MacTel).

15 Mar 2016

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Researchers report photoimmunotherapy to be effective against elusive gastric cancer cells following transduction with the gene that expresses the extracellular domain protein of HER2. The results are published in the journal Small Molecule Therapeutics in February 2016.

15 Mar 2016

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Addition of lapatinib to trastuzumab improves responses in women with newly diagnosed, HER2-positive breast cancer who receive the combination prior to undergoing surgery, suggests research.

14 Mar 2016

Study: Nearly 29% of cancer survivors suffer financial burden

An analysis of US data from 2011 indicates that nearly 29 percent of cancer survivors are financially burdened as a result of their cancer diagnosis and/or treatment. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also reveals that such hardships can have lasting physical and mental effects on cancer survivors.

14 Mar 2016

Paroxysmal AF patients who practice yoga have better quality of life

Yoga improves quality of life in patients with paroxysmal atrial fibrillation, according to research published today in the European Journal of Cardiovascular Nursing. Heart rate and blood pressure also decreased in patients who did yoga.

14 Mar 2016

Newly identified RNA biomarkers open door for simple, accurate non-invasive test for prostate cancer

A study on non-coding RNA (Ribonucleic Acid) from prostate cancer patients has identified a series of new prostate cancer markers which can be found in urine. Combining these RNA markers into a single test potentially opens the door for simple, accurate non-invasive testing for prostate cancer.

14 Mar 2016

Use of contralateral prophylactic mastectomy tripled from 2002 to 2012 despite no survival benefit

The use of contralateral prophylactic mastectomy (CPM), the surgical removal of a breast unaffected by cancer as part of the course of treatment for breast cancer, has more than tripled from 2002 to 2012 despite evidence suggesting no survival benefit over breast conservation, according to a new study from Brigham and Women's Hospital published in Annals of Surgery on March 11, 2016.

14 Mar 2016

TRPV2 could be a target for obesity therapy

Brown adipose tissue (BAT), a major site for mammalian non-shivering thermogenesis, could be a target for prevention and treatment of human obesity. Transient receptor potential vanilloid 2 (TRPV2), a Ca2+-permeable cation channel, plays vital roles in the regulation of various cellular functions.

14 Mar 2016

Synthetic nanoparticle can light up and treat atherosclerotic plaques

Atherosclerosis, a disease in which plaque builds up inside arteries, is a prolific and invisible killer, but it may soon lose its ability to hide in the body and wreak havoc. Scientists have now developed a nanoparticle that functionally mimics nature's own high-density lipoprotein (HDL). The nanoparticle can simultaneously light up and treat atherosclerotic plaques that clog arteries. Therapy with this approach could someday help prevent deadly heart attacks and strokes.

14 Mar 2016

Tai chi exercise improves outcomes in older fallers

Recently, researchers compared the effects of tai chi to leg strengthening exercises (a physical therapy called "lower extremity training," or LET) in reducing falls. Falls are a leading cause of serious injuries in older adults and can lead to hospitalization, nursing home admission, and even death.

13 Mar 2016

FDA approves Xalkori (crizotinib) to treat patients with ROS-1 positive NSCLC

The U.S. Food and Drug Administration today approved Xalkori (crizotinib) to treat people with advanced (metastatic) non-small cell lung cancer (NSCLC) whose tumors have an ROS-1 gene alteration. Xalkori is the first and only FDA approved treatment for patients with ROS-1 positive NSCLC.

13 Mar 2016

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Researchers have shown for the first time that it is possible to use a multi-gene test to identify patients with early breast cancer who can be spared chemotherapy and who will still be alive and well five years after diagnosis.

11 Mar 2016

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

microRNAs (miRs) are small endogenous noncoding RNA molecules (20–23 nucleotides) derived from imperfectly paired hairpin RNA structures naturally encoded in the genome that act specifically as triggering molecules to control translational repression or mRNA degradation.

11 Mar 2016

Salvage radical prostatectomy can improve outcomes in prostate cancer patients

Approximately 14 percent of men will be diagnosed with prostate cancer at some point in their lifetimes, according to the National Institutes of Health. Radiation therapy traditionally has been a primary treatment for the cancer, but one-fourth of men have a recurrence of prostate cancer within five years after the therapy.

11 Mar 2016

Once-daily nutritional drink can help reduce brain shrinkage in prodromal AD patients

Topline results from the European LipiDiDiet clinical trial were presented today as part of a late-breaking presentation at the Advances in Alzheimer's Therapy congress.

11 Mar 2016

Experts to analyse latest advances in diagnosis, treatment of soft tissue sarcoma at PharmaMar seminar

The creation of a network of centres of reference and adopting measures that promote research and access to treatments are two key aspects for improving the prognosis of patients with soft tissue sarcoma (STS), an uncommon type of cancer that originates in the tissues that connect, support and surround other body structures, such as muscles, fat, blood vessels, nerves, tendons and lining of the joints.

11 Mar 2016

New development offers hope to patients with inoperable advanced midgut neuroendocrine cancer

A novel drug proven to reduce the risk of disease progression by 79% as well as three new European Centres of Excellence, offer new hope to patients with inoperable metastatic advanced midgut neuroendocrine cancer.

11 Mar 2016

New study shows that structural changes within the spine alter vibration response

Magnetic resonance image isn't everything. A new University of Alberta study shows that vibrating the spine may reveal more when it comes to treating back pain. Teaming with the University of South Denmark to study the lumbar spine of twins, Greg Kawchuk and his team demonstrate that structural changes within the spine alter its vibration response significantly.

11 Mar 2016

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss.

11 Mar 2016

Therapy News and Research

Alcohol consumption may increase risk for breast cancer

Drugs to help energy-starved photoreceptors offers new avenue for treating AMD , MacTel

Combining photoimmunotherapy and gene transduction effective against elusive gastric cancer cells

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Study: Nearly 29% of cancer survivors suffer financial burden

Paroxysmal AF patients who practice yoga have better quality of life

Newly identified RNA biomarkers open door for simple, accurate non-invasive test for prostate cancer

Use of contralateral prophylactic mastectomy tripled from 2002 to 2012 despite no survival benefit

TRPV2 could be a target for obesity therapy

Synthetic nanoparticle can light up and treat atherosclerotic plaques

Tai chi exercise improves outcomes in older fallers

FDA approves Xalkori (crizotinib) to treat patients with ROS-1 positive NSCLC

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Delivering microRNAs in cancer treatment: an interview with Dr Conde and Prof Artzi

Salvage radical prostatectomy can improve outcomes in prostate cancer patients

Once-daily nutritional drink can help reduce brain shrinkage in prodromal AD patients

Experts to analyse latest advances in diagnosis, treatment of soft tissue sarcoma at PharmaMar seminar

New development offers hope to patients with inoperable advanced midgut neuroendocrine cancer

New study shows that structural changes within the spine alter vibration response

Low bone mass higher in HIV-infected males than in females

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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