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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

A new batch of prognostic cancer biomarkers have been discovered in an area where few have gone looking before. Researchers have unveiled a catalogue of 166 prognostic biomarkers, generated by analyzing long non-coding RNAs (lncRNAs) – which are understudied in cancer research.

15 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Potential biomarkers of coagulopathy and disease severity in COVID-19

Scientists have investigated the presence of specific biomarkers in hospitalized COVID-19 patients

15 Nov 2021

Reflex app works like a pupillometer to identify concussion biomarkers

Evaluating concussion patients for recovery and measuring compounding injuries can be done as simply as recording a video with a smartphone.

12 Nov 2021

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research presented at the NCRI Festival.

11 Nov 2021

Protein in the blood could predict type 2 diabetes many years before diagnosis

A large study led by Lund University in Sweden has identified a protein in the blood that could predict type 2 diabetes up to nineteen years before the onset of the disease.

11 Nov 2021

New biomarkers could help determine synaptic damage and neurodegeneration in Alzheimer's

Alzheimer's disease is the main neurodegenerative disease in old people for which there is no treatment or efficient prevention yet.

10 Nov 2021

MRI brain imaging biomarkers bring new levels of precision for prescribing antidepressants

Research led by UT Southwestern has identified MRI brain imaging biomarkers that bring new levels of precision for prescribing the most effective antidepressants.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Prostate cancer urine test identifies men who can safely avoid immediate treatment

Researchers at the University of East Anglia have shown that a prostate cancer urine test can identify men at 'intermediate risk' who can safely avoid immediate treatment and benefit from 'active surveillance' instead.

2 Nov 2021

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

The immune checkpoint protein B7-H3 may be a promising new target for immunotherapy in treatment-resistant prostate cancers, according to two new studies led by researchers at the Johns Hopkins Kimmel Cancer Center.

2 Nov 2021

Chromosome aberrations linked to acute toxicities in esophageal cancer patients

Japanese researchers identified chromosome aberrations as a new biomarker in predicting an esophageal cancer patient's risk of experiencing severe chemoradiotherapy side effects.

28 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

Experts create deep learning network capable of detecting disease biomarkers with high accuracy

Researchers are developing a deep learning network capable of detecting disease biomarkers with a much higher degree of accuracy.

28 Oct 2021

Scientists flip a new piece in the male infertility puzzle

Scientists at Cincinnati Children's appear to have flipped another piece in the underexplored puzzle of male infertility.

27 Oct 2021

Genetic biomarker test predicts how men with high-risk prostate cancer will respond to treatment

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

25 Oct 2021

Role of SARS-CoV-2 infection biomarkers in HIV replication

A new study investigates the role of the S100A8/A9 complex in the replication of HIV.

25 Oct 2021

Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues

A new study aimed to determine whether ACE2 targeting drugs change the tissue levels of ACE2 in healthy mice.

25 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Study analyzes neural correlates of balance in individuals with traumatic brain injury

Using neuroimaging techniques and electroencephalography (EEG), Kessler Foundation researchers compared the neural correlates of balance in individuals with traumatic brain injury and matched controls. This study is the first to report EEG-based functional connectivity measures during a balance perturbation task and show the association with white matter integrity in the brain.

21 Oct 2021

Biomarker News and Research

Further Reading

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

Study offers new insight into the role of tau proteins in ALS pathogenesis

Potential biomarkers of coagulopathy and disease severity in COVID-19

Reflex app works like a pupillometer to identify concussion biomarkers

Regular blood tests can identify prostate cancer patients who are resistant to treatment

Protein in the blood could predict type 2 diabetes many years before diagnosis

New biomarkers could help determine synaptic damage and neurodegeneration in Alzheimer's

MRI brain imaging biomarkers bring new levels of precision for prescribing antidepressants

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Prostate cancer urine test identifies men who can safely avoid immediate treatment

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

Chromosome aberrations linked to acute toxicities in esophageal cancer patients

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Experts create deep learning network capable of detecting disease biomarkers with high accuracy

Scientists flip a new piece in the male infertility puzzle

Genetic biomarker test predicts how men with high-risk prostate cancer will respond to treatment

Role of SARS-CoV-2 infection biomarkers in HIV replication

Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Study analyzes neural correlates of balance in individuals with traumatic brain injury

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

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