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Light-activated drug delivery holds promise for treating cancer

Researchers from UCLA's Jonsson Comprehensive Cancer Center have developed an innovative cancer-fighting technique in which custom-designed nanoparticles carry chemotherapy drugs directly to tumor cells and release their cargo when triggered by a two-photon laser in the infrared red wavelength.

3 Mar 2014

Sunburn causes melanoma through direct and indirect processes

Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.

3 Mar 2014

Standard nomenclature of insect brains may improve future research on brain function and disease

When you're talking about something as complex as the brain, the task isn't any easier if the vocabula

3 Mar 2014

PerkinElmer launches Lamina slide scanner for clearer visualization of protein biomarker in tissue

PerkinElmer, Inc., a global leader focused on the health and safety of people and the environment, today announced the launch of the Lamina multilabel slide scanner at the USCAP 2014 Annual Meeting.

3 Mar 2014

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

A protein that controls the metamorphosis of the common fruit fly could someday play a role in reversing brain injuries, said Duke University researchers.

28 Feb 2014

Cedars-Sinai researchers develop unique imaging device to "light up" malignant brain tumors

Researchers at the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Department of Neurosurgery have developed a unique, compact, relatively inexpensive imaging device to "light up" malignant brain tumors and other cancers.

27 Feb 2014

Researchers create new probe that freezes cells to "see" at greater detail without damaging

It's an odd twist. For scientists to determine if a cell is functioning properly, they must destroy it. This is what happens in X-ray fluorescence microscopy when biological specimens are exposed to ionizing radiation, which provides images with a level of detail that conventional microscopes just can't match.

26 Feb 2014

Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

The findings of a recent study indicate that routine testing with both fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC) may enhance the detection of ALK-positive non-small cell lung cancer (NSCLC).

25 Feb 2014

Researchers develop novel technique for detecting ALK rearrangements in non-small cell lung cancers

Researchers have developed a novel technique for detecting ALK rearrangements in non-small cell lung cancers (NSCLCs) that is more sensitive and easier to perform than currently available techniques.

25 Feb 2014

New system delivers anti-inflammatory drugs to immune cells gone out of control

Researchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology.

24 Feb 2014

Researchers produce novel microparticles

A team of researchers of Karlsruhe Institute of Technology (KIT) and the University of Michigan/USA has produced novel microparticles, whose surface consists of three chemically different segments.

24 Feb 2014

New innovative technique can carry chemotherapy safely and release inside cancer cells

Researchers from the cancer nanotechnology and signal transduction and therapeutics programs of UCLA's Jonsson Comprehensive Cancer Center (JCCC) have developed an innovative technique that can carry chemotherapy safely and release it inside cancer cells when triggered by two-photon laser in the infrared red wave length.

24 Feb 2014

Study on Zebrafish neurons could lead to better understanding of birth defects in humans

The zebrafish, a tropical freshwater fish similar to a minnow and native to the southeastern Himalayan region, is well established as a key tool for researchers studying human diseases, including brain disorders.

21 Feb 2014

Researchers develop new method to obtain three chemically different patches on same microparticle

Micromachines, nanorobots, multifunctional drug transporters, and matrices for tissue growth – these and many other applications would benefit from three-dimensional microstructures that present different (bio)chemical ligands that offer control over directionality. In the journal Angewandte Chemie, a team of German and American researchers has now reported the production of microparticles whose surface consists of three separate areas (“patches”) that can be decorated with three different (bio)molecules.

21 Feb 2014

Researchers receive $3M grant to develop targeted cancer drugs and repair damaged arteries

The National Institutes of Health has awarded grants totaling $3 million for two nanoparticle research projects in which Penn State bioengineer Jian Yang is co-principal investigator.

19 Feb 2014

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

Phase Focus Ltd (Phasefocus), the company that is revolutionizing microscopy and imaging with the Phasefocus Virtual Lens® technology, reports on the Celldance competition results held at the recent annual ASCB meeting. KTP associate, Dr Rakesh Suman, was runner up with his video entitled "Cellular Heaven & Hell."

From Phase Focus Limited 18 Feb 2014

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

The elusive progenitor cells that give rise to innate lymphoid cells-a recently discovered group of infection-fighting white blood cells-have been identified in fetal liver and adult bone marrow of mice, researchers from the University of Chicago report early online in the journal Nature.

14 Feb 2014

Rice, UTMB develop diagnostic test for cryptosporidiosis

Bioengineers at Rice University and the University of Texas Medical Branch (UTMB) at Galveston have developed a simple, highly sensitive and efficient test for the diarrheal disease cryptosporidiosis that could have great impact on global health.

7 Feb 2014

Scientists develop fully automated system to identify sepsis in infants within hours

New detection methods could shorten the detection of sepsis from days down to only a few hours. Sepsis is a possibly mortal bacterial infection. It affects neonates and young infants more severely since their immune system is not fully developed. Now scientists are developing a fully automated system, which can identify sepsis in infants within hours instead of days.

5 Feb 2014

Drug used to treat schizophrenia, dementia has potential for treating liver disease

Opening up a can of worms is a good way to start hunting for new drugs, recommend researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine.

4 Feb 2014

Fluorescence News and Research

Light-activated drug delivery holds promise for treating cancer

Sunburn causes melanoma through direct and indirect processes

Standard nomenclature of insect brains may improve future research on brain function and disease

PerkinElmer launches Lamina slide scanner for clearer visualization of protein biomarker in tissue

Protein that controls Drosophila nervous system may play role in reversing brain injuries in human

Cedars-Sinai researchers develop unique imaging device to "light up" malignant brain tumors

Researchers create new probe that freezes cells to "see" at greater detail without damaging

Study: Routine testing with FISH and IHC may enhance detection of ALK-positive NSCLC

Researchers develop novel technique for detecting ALK rearrangements in non-small cell lung cancers

New system delivers anti-inflammatory drugs to immune cells gone out of control

Researchers produce novel microparticles

New innovative technique can carry chemotherapy safely and release inside cancer cells

Study on Zebrafish neurons could lead to better understanding of birth defects in humans

Researchers develop new method to obtain three chemically different patches on same microparticle

Researchers receive $3M grant to develop targeted cancer drugs and repair damaged arteries

Phasefocus’ KTP associate Dr Suman receives runners up spot for Cellular Heaven and Hell time-lapse video

Elusive progenitor cells that give rise to ILCs identified in fetal liver and bone marrow of mice

Rice, UTMB develop diagnostic test for cryptosporidiosis

Scientists develop fully automated system to identify sepsis in infants within hours

Drug used to treat schizophrenia, dementia has potential for treating liver disease

Choosing the right benchtop fluorescence microscope: A practical buyer's guide eBook

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