Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

A recent study evaluated the molecular and histopathological effects in the placenta following a SARS-CoV-2 infection during pregnancy.

28 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers - and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Crucial regulator of malaria parasite transmission identified

Malaria remains one of the biggest global public health challenges. It kills a young child every two minutes, more than any other infectious disease.

25 Feb 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Study provides a promising new avenue for development of anti-obesity treatments

An anti-tumor drug promotes weight loss in mice at low doses by activating a natural hunger-suppressing pathway, according to a new study publishing February 24th in the open-access journal PLOS Biology by Jiang Wei Wu and colleagues at Northwest A&F University in Shaanxi, China.

24 Feb 2022

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

CD91 receptor promotes SARS-CoV-2 infection

researchers find that LRP1/CD91 is a leading molecule in virus-host cell interactions that causes infection by many RNA viruses.

22 Feb 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Combating leukemia cells by disrupting their energy maintenance mechanism

Acute myeloid leukemia, which affects blood and bone marrow cells, is a particularly dangerous form of cancer. More than half of patients under the age of 60 die.

17 Feb 2022

Researchers discover a new and unconventional nuclear function for cancer microRNA

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Zebrafish model reveals how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Biomarker could predict pathologic response to chemotherapy among bladder cancer patients

Long-term survival data from the first prospective, randomized biomarker validation trial in patients with muscle-invasive bladder cancer being treated with cisplatin-based chemotherapy before surgery will be reported at the 2022 Genitourinary Cancers Symposium of the American Society of Clinical Oncology (GU ASCO) on February 18, 2022.

15 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Gene Expression News and Research

Further Reading

Novel mechanism that connects circadian rhythm and muscle repair discovered

Histopathologic and molecular effects in the placenta after SARS-CoV-2 infection during pregnancy

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Crucial regulator of malaria parasite transmission identified

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Study provides a promising new avenue for development of anti-obesity treatments

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Why is it Important to Democratize Proteomics Data?

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

CD91 receptor promotes SARS-CoV-2 infection

Scientists use entire human GI tracts to shed light on cellular functions

The logic that controls gene regulation in human cells discovered

Combating leukemia cells by disrupting their energy maintenance mechanism

Researchers discover a new and unconventional nuclear function for cancer microRNA

Zebrafish model reveals how early embryo cells begin to independently produce proteins

Biomarker could predict pathologic response to chemotherapy among bladder cancer patients

Researchers create a comprehensive atlas of cerebrovascular cell types

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