Immune System News and Research

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Combination therapy shows great promise as a new strategy against advanced lung cancer

Adding an anti-inflammatory drug to anti-PD1 checkpoint inhibitor immunotherapy has shown great promise as a new strategy against advanced lung cancer, based on results from a small clinical trial led by investigators at the Abramson Family Cancer Center at the University of Pennsylvania Perelman School of Medicine.

21 Jun 2024

Pennington Biomedical researchers partner on award-winning long COVID study

Dr. John Kirwan, Executive Director of Pennington Biomedical Research Center, is serving as a co-principal investigator on the Pathobiology in RECOVER of Metabolic and Immune Systems, or PROMIS, study.

21 Jun 2024

Cannabis use tied to increased risk of severe COVID-19

As the deadly disease that came to be known as COVID-19 started spreading in late 2019, scientists rushed to answer a critical question: Who is most at risk?

21 Jun 2024

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

Patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas (NHLs) who received frequent tests for immunoglobulin G (IgG) were less likely to experience severe infections compared with those who didn't, according to a study published in Blood Advances.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Combining JAK inhibitors with checkpoint inhibitors improves cancer immunotherapy response

Because not all cancer patients respond to a leading type of cancer immunotherapy drug, known as an immune checkpoint inhibitor, scientists explored whether adding janus kinase (JAK) inhibitors – drugs that treat chronic inflammation – could help.

20 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Less healthy intestinal flora could increase the risk of serious infection

The composition of the intestinal flora can predict the chances of developing serious infections such as pneumonia.

20 Jun 2024

Unveiling the role of auto-antibodies in COVID-19 severity

Even though COVID-19 manifests as a mild and short-lived disease in most people, some suffer extremely severe symptoms; in the worst cases, these patients die due to complications such as respiratory failure or thromboembolism.

19 Jun 2024

Harnessing post-translational modifications for a tuberculosis booster vaccine

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide.

19 Jun 2024

Perinatal depression linked to higher long-term cardiovascular disease risk in women

Women diagnosed with perinatal depression are more likely to develop cardiovascular disease in the following 20 years compared to women who have given birth without experiencing perinatal depression, according to research published in the European Heart Journal today (Wednesday).

19 Jun 2024

Unlocking the role of B cells in neuromyelitis optica spectrum disorder treatment

Autoimmune diseases cannot currently be cured, only treated, and this is also true for neuromyelitis optica spectrum disorder, which affects the central nervous system.

19 Jun 2024

New Swiss research institute to pioneer immune engineering and global child health

“Swiss research institute established to focus on immune engineering and advancing global child and adolescent health.”

19 Jun 2024

Discovery of mobile regulatory T cells could revolutionize disease treatment

Scientists at the University of Cambridge have discovered that a type of white blood cell - called a regulatory T cell - exists as a single large population of cells that constantly move throughout the body looking for, and repairing, damaged tissue.

18 Jun 2024

Personalized medicine approaches for sepsis based on immune response profiling

Sepsis patients could be treated based on their immune system's response to infection, not their symptoms.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Immune System News and Research

Combination therapy shows great promise as a new strategy against advanced lung cancer

Pennington Biomedical researchers partner on award-winning long COVID study

Cannabis use tied to increased risk of severe COVID-19

Regular IgG monitoring and replacement therapy reduce severe infections in CLL and NHL patients

Using deep learning to design synthetic soluble versions of cell membrane proteins

Combining JAK inhibitors with checkpoint inhibitors improves cancer immunotherapy response

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Less healthy intestinal flora could increase the risk of serious infection

Unveiling the role of auto-antibodies in COVID-19 severity

Harnessing post-translational modifications for a tuberculosis booster vaccine

Perinatal depression linked to higher long-term cardiovascular disease risk in women

Unlocking the role of B cells in neuromyelitis optica spectrum disorder treatment

New Swiss research institute to pioneer immune engineering and global child health

Discovery of mobile regulatory T cells could revolutionize disease treatment

Personalized medicine approaches for sepsis based on immune response profiling

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Innovative bread formulation shows promise in preventing asthma

Global Omega-3 Index map update reveals persistent data gaps and low levels

St. Jude researchers uncover NLRC5's role in immune response and cell death

TIMP-1 protein found to boost immune system's fight against cancer

Immunology eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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