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Mature liver cells trigger regeneration in response to neighboring injury

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 deaths occur each year due to acetaminophen overuse and liver failure.

8 May 2025

New stem cell model mimics alpha cell behavior in diabetic conditions

Mor than 800 million people worldwide are living with diabetes, according to World Health Organization (WHO) estimates, with numbers steadily increasing.

8 May 2025

New immunotherapy target found in pancreatic cancer cells

Researchers from MIT and Dana-Farber Cancer Institute have discovered that a class of peptides expressed in pancreatic cancer cells could be a promising target for T-cell therapies and other approaches that attack pancreatic tumors.

8 May 2025

Wildlife trade, not bats, likely moved the ancestors of SARS-CoV-2 to humans

New genetic analyses reveal that the bat virus ancestors of SARS-CoV-1 and SARS-CoV-2 likely circulated in Western China or Northern Laos just years before human outbreaks. Their rapid appearance thousands of kilometers away suggests wildlife trade, not bat migration, was the likely transmission path.

8 May 2025

Eating avocado in pregnancy cuts infant food allergy risk by nearly half

Pregnant women who ate avocado were significantly less likely to have children with food allergies at 12 months of age. The association held even after adjusting for maternal diet quality, lifestyle, and perinatal factors in a large Finnish cohort.

8 May 2025

Cancer rates are climbing in younger adults and researchers want to know why

A new NIH-led study finds rising rates of 14 cancer types in Americans under 50, especially breast, colorectal, kidney, uterine, and pancreatic cancers. The research urges deeper investigation into shared risk factors and earlier screening strategies.

8 May 2025

Study identifies key enzyme linked to metastasis in head and neck cancer

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC).

8 May 2025

Researchers target weakness in pathogens causing tropical diseases

Researchers are zeroing in on the Achilles’ heel of pathogens that cause Chagas disease, sleeping sickness and leishmaniasis.

8 May 2025

Study uncovers how co-infection by two bacteria suppresses immune response

The incidence of infection by Mycobacterium abscessus, is increasing in patients with cystic fibrosis, chronic obstructive pulmonary disease (COPD), and other chronic pulmonary diseases, leading to an accelerated lung function decline.

8 May 2025

Monoclonal antibody protects mice from lethal influenza A doses

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows.

8 May 2025

Next-generation "armored" CAR T cell therapy shows promising results in lymphoma patients

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially available CAR T cell therapies.

8 May 2025

Scientists enhance T cell immunity for more durable vaccines

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines for viruses and enhanced cancer therapies.

7 May 2025

Macrophages take center stage in liver healing after injury

The liver is famous for its remarkable ability to regenerate, but that healing power depends heavily on the actions of its resident immune cells. A new study spotlights macrophages, the liver's cleanup and repair specialists, revealing that these cells quickly adapt after injury to clear debris and support tissue recovery.

7 May 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

AI identifies brain cell types through electrical signatures

A decades-old challenge in neuroscience has been solved by harnessing artificial intelligence (AI) to identify the electrical signatures of different types of brain cells for the first time, as part of a study in mice led by researchers from UCL.

7 May 2025

Uncovering the architecture of the human sugar sensor

Our attraction to sugar has grown to an unhealthy level. The average person in the United States now consumes more than 100 pounds of the sweet stuff every year, up from 18 pounds in 1800.

7 May 2025

Researchers trace origins of aggressive childhood brain tumors

Medulloblastoma is one of the most common malignant tumors of the central nervous system (CNS) in children and adolescents. It develops in the area of the cerebellum, which is responsible for movement coordination, among other things.

7 May 2025

New micropipette allows precise ion delivery to individual brain cells

Researchers at Linköping University have developed a new type of pipette that can deliver ions to individual neurons without affecting the sensitive extracellular milieu.

7 May 2025

New insights into bacterial division through engineered protein control

The Min protein system prevents abnormal cell division in bacteria by forming oscillating patterns between the ends of a cell ("poles"). Despite decades of theoretical work, predicting the protein concentrations at which oscillations start and whether cells can maintain them under different conditions has been a challenge.

7 May 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025