Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Simvastatin may help sufferers with Alzheimer's

Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in humans, significantly improved spatial memory - how to navigate a water maze - in mice genetically bred to have an Alzheimer's like disease.

1 May 2007

Estrogen fluctuation affects epileptic seizures

In more than a third of women with epilepsy, seizures fluctuate across the menstrual cycle, due in part to continually fluctuating effects of estrogen on the neural circuitry in the hippocampus, a region of the brain involved in learning and memory - and in epileptic seizures.

1 May 2007

New method allows for stem cell propagation and neurogenesis in cell culture

Researchers are now able to study stem cells from the brains of adult mice and their neurogenesis in long-term cell cultures.

26 Apr 2007

Internal part of prefrontal cortex identified as key structure for memory formation

Does a specific memory exist for events involving humans, French researchers from the Vulnerability, Adaptation and Psychopathology Laboratory (CNRS/Universit' Paris VI) and Canadian researchers from Douglas Hospital, McGill University (Montreal) have identified the internal part of the prefrontal cortex as the key structure for the memory formation of social information.

19 Apr 2007

Research shows potential for treatment of diabetics in hypoglycemic coma

Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center.

5 Apr 2007

Study explains exactly how exposure to lead during brain development produces learning deficits

A study of young adult rats by researchers from the Johns Hopkins Bloomberg School of Public Health provides evidence that explains exactly how exposure to lead during brain development produces learning deficits.

3 Apr 2007

Halting neurogenesis improves working memory in mice

New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago events, may have a harder time with word recall or remembering the day's current events.

3 Apr 2007

Precise region in the frontal cortex may be specialised for learning social information

Is there a specific memory for events involving people Researchers in the Vulnerability, Adaptation and Psychopathology Laboratory (CNRS/University Paris VI France ) and a Canadian team at Douglas Hospital, McGill University (Montreal), have identified the internal part of the prefrontal cortex as being the key structure for memorising social information.

2 Apr 2007

Severe stress can damage a child's brain

According to researchers in the U.S. children who suffer severe stress may also suffer damage to their brains.

5 Mar 2007

TrkB and its role in learning and memory

For the first time researchers investigate the molecular basis of memory in living mice.

9 Jan 2007

Researchers use gene therapy to reduce the development of epileptic seizures

For the first time, researchers have inhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signaling pathways in the brain, neurology researchers found that they could significantly reduce the development of epileptic seizures in rats.

8 Nov 2006

Research sheds light on episodic memory

Memories of events comprise many components--including sights, sounds, smells, and tastes. Somehow the many features of an episodic memory are woven together into a coherent whole, and researchers have had little understanding of how this binding takes place as the memories are processed by the brain's memory center, the hippocampus.

8 Nov 2006

Gentle electric currents stimulate the brain and boost the memory

German scientists say they have found that gentle electric currents which stimulate the brain while sleeping can boost the memory.

6 Nov 2006

Link discovered between common cold viruses and Alzheimer's disease

According to new research memory loss and Alzheimer's disease may be linked to the very viruses which cause the common cold.

24 Oct 2006

Gene called Kibra plays an important role in memory

Researchers at the Translational Genomics Research Institute (TGen) have announced the discovery of a gene that plays a significant role in memory performance in humans.

20 Oct 2006

Food like an addictive drug for some people

Researchers in the U.S. have found that the same brain circuits are involved when obese people fill their stomachs as when drug addicts think about drugs and the discovery they say suggests an association between overeating and addiction.

3 Oct 2006

Research implicates brain circuits involved in drug craving and emotional response to food

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have found new clues to how the brain and the stomach interact with emotions to cause overeating and obesity.

2 Oct 2006

Anticipation plays a powerful role in human memory

Psychologists have long known that memories of disturbing emotional events - such as an act of violence or the unexpected death of a loved one - are more vivid and deeply imprinted in the brain than mundane recollections of everyday matters.

4 Sep 2006

A wake-up call for parents of children with sleep apnea

In what is believed to be the first study showing neural changes in the brains of children with serious, untreated sleep apnea, Johns Hopkins researchers conclude that children with the disorder appear to suffer damage in two brain structures tied to learning ability.

31 Aug 2006

The endocannabinoid system controls key epileptogenic circuits in the hippocampus

The same brain machinery that responds to the active substance in marijuana provides a central "on-demand" protection against seizures, researchers have found. They said their discoveries suggest that the "endocannabinoid" system might constitute a prime target for drugs against seizures of epilepsy and other neurodegenerative diseases.

16 Aug 2006