Clinical Trial News and Research

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Financial incentives can improve smoking cessation among socioeconomically disadvantaged adults

A study published today by a University of Oklahoma researcher shows that financial incentives can make a big difference in helping smokers quit.

2 Jul 2024

Children consuming more isoflavones from soy foods exhibit better thinking abilities and attention

A new study found that school-aged children who consumed more isoflavones from soy foods exhibited better thinking abilities and attention.

2 Jul 2024

NIH launches Phase 1 trial for innovative nasal COVID-19 vaccine

A Phase 1 trial testing the safety of an experimental nasal vaccine that may provide enhanced breadth of protection against emerging variants of SARS-CoV-2, the virus that causes COVID-19, is now enrolling healthy adults at three sites in the United States.

1 Jul 2024

Strawberry fruit intake may improve glucose control and reduce CVD risk

Strawberries, America's favorite fruit, are top for consumers in taste, and research shows that they may be a good choice in promoting heart health as well.

1 Jul 2024

Simple exercises can prevent nerve damage during cancer treatments

Cancer treatments often cause nerve damage that can lead to long-lasting symptoms. Medication has proven ineffective in these cases.

1 Jul 2024

Efficacy of acupuncture in improving sleep quality for Parkinson's patients

Whether acupuncture improves sleep quality in Parkinson's patients.

1 Jul 2024

Innovative dementia cost model to aid families and shape health policy

An A-list of researchers from across USC is building a dementia cost model that will generate comprehensive national, annual estimates of the cost of dementia that could benefit patients and their families, thanks to a five-year, $8.2 million federal grant from the National Institute on Aging.

28 Jun 2024

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes.

28 Jun 2024

Gene therapy milestone at SickKids offers hope for children with SPG50 neurodegenerative disorder

When Michael Pirovolakis received an individualized gene therapy in a single-patient clinical trial at The Hospital for Sick Children (SickKids) in March 2022, the course of his condition was dramatically altered.

28 Jun 2024

Clinical trial seeks to evaluate safety of new EV-D68 treatment

The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe respiratory and neurological diseases such as acute flaccid myelitis (AFM) – similar to polio. Scientists are striving to better understand AFM, which has emerged in the United States with spikes in cases every other year, primarily in the late-summer months over the last decade.

28 Jun 2024

Antibody-drug conjugate effective, less toxic for stage 1 HER2+ breast cancer

A year of treatment with a medicine made of an antibody and chemotherapy drug has proven highly effective in preventing stage 1 HER2-positive breast cancer from recurring in patients, a team led by Dana-Farber Cancer Institute researchers has found.

28 Jun 2024

New study reveals how GLP-1 receptor agonists enhance preingestive fullness

GLP-1 receptor agonists promote the feeling of fullness before eating via neurons in the dorsomedial hypothalamus, according to a new study. The findings offer new insights into the neural pathways by which GLP-1 receptor agonists increase the feeling of fullness to prevent overconsumption of food, which is key in mitigating obesity. Glucagon-like-peptide-1 (GLP-1) plays an important role in signaling the feeling of fullness after eating.

27 Jun 2024

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Results from a new study led by researchers at The University of Texas MD Anderson Cancer Center support standard use of the more precise intensity-modulated radiotherapy (IMRT) over the alternative 3D-conformal radiotherapy (3D-CRT) for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC).

27 Jun 2024

$Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers$

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

27 Jun 2024

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Combining exercise with GLP-1 RA liraglutide results in significant weight loss while preserving bone health in adults with obesity.

27 Jun 2024

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

New research led by UCLA Health confirms that both Tai Chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.

26 Jun 2024

NIAID scientists discover probiotic treatment for eczema

NIAID research has led to the availability of a new over-the-counter topical eczema probiotic.

26 Jun 2024

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

The injectable antiretroviral drug lenacapavir was safe and 100% effective as long-acting HIV pre-exposure prophylaxis (PrEP) among cisgender women in a Phase 3 clinical trial, according to top-line findings released by Gilead Sciences, Inc., the study sponsor.

26 Jun 2024

Chemotherapy's cognitive side effects tied to gut microbiome disruption

Chemotherapy is known to cause behavioral side effects, including cognitive decline. Notably, the gut microbiome communicates with the brain to affect behavior, including cognition.

26 Jun 2024

Methylphenidate may enhance oculomotor function in individuals with multiple sclerosis

A pilot study conducted by Kessler Foundation researchers has shown promising results in the use of methylphenidate to enhance oculomotor function in individuals with multiple sclerosis (MS).

26 Jun 2024

Clinical Trial News and Research

Financial incentives can improve smoking cessation among socioeconomically disadvantaged adults

Children consuming more isoflavones from soy foods exhibit better thinking abilities and attention

NIH launches Phase 1 trial for innovative nasal COVID-19 vaccine

Strawberry fruit intake may improve glucose control and reduce CVD risk

Simple exercises can prevent nerve damage during cancer treatments

Efficacy of acupuncture in improving sleep quality for Parkinson's patients

Innovative dementia cost model to aid families and shape health policy

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Gene therapy milestone at SickKids offers hope for children with SPG50 neurodegenerative disorder

Clinical trial seeks to evaluate safety of new EV-D68 treatment

Antibody-drug conjugate effective, less toxic for stage 1 HER2+ breast cancer

New study reveals how GLP-1 receptor agonists enhance preingestive fullness

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

NIAID scientists discover probiotic treatment for eczema

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

Chemotherapy's cognitive side effects tied to gut microbiome disruption

Methylphenidate may enhance oculomotor function in individuals with multiple sclerosis

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