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Novel antisense drug shows promise to improve health of people with NAFLD

Using a first-of-its-class drug in a clinical trial, an international research effort headed by a scientist at University of California San Diego School of Medicine reports that inhibition of a key enzyme safely and effectively improved the health of persons with non-alcoholic fatty liver disease, a chronic metabolic disorder that affects hundreds of millions of people worldwide.

16 Jun 2020

Breakthrough drug significantly delays onset of type 1 diabetes, study finds

Emily Sims, M.D. today shared new findings that a breakthrough drug significantly delays the onset of type 1 diabetes (T1D).

15 Jun 2020

Experimental drug to prevent deadly blood coagulation in patients with COVID-19

The British Heart Foundation is funding a trial for an experimental drug that could prevent the life-threatening blood clots that are seen in the lungs of the patients with COVID-19 or those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The drug named TRV027 is said to normalize the hormonal imbalance that can be seen in patients developing COVID-19, experts said.

15 Jun 2020

UIC clinical trial to soon test a vaccine for COVID-19

The University of Illinois at Chicago will soon test a vaccine for COVID-19.

15 Jun 2020

BCG vaccination strengthens the immune system

A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections. While this effect has been recognized for a long time, it is not known what causes it.

15 Jun 2020

Hydroxychloroquine shows no antiviral effect on SARS-Cov-2 in non-human primate models

A study on the effects of hydroxychloroquinei n macaques infected with the SARS-CoV-2 virus, , used alone or in combination with azithromycin, have been pre-published on Research Square, after their submission to Nature.

12 Jun 2020

Study initiates hydroxychloroquine clinical trial to prevent COVID-19 in healthy people

Rush University Medical Center has opened enrollment for a new clinical trial investigating whether the drug hydroxychloroquine is better than a placebo in preventing COVID-19 infection in healthy people working in health care settings.

12 Jun 2020

Aspirin reduces hereditary colorectal cancer risk

Aspirin reduces colorectal cancer risk by half in individuals at high genetic risk. Preventive efficacy is prolonged for 10-20 years after treatment with aspirin.

11 Jun 2020

Antihypotensive agent for sepsis disrupts the immune system, increases susceptibility to infections

Patients who go into shock caused by sepsis (septic shock) are treated with the antihypotensive agent norepinephrine.

11 Jun 2020

Age-related structural brain changes are linked to hormone-level changes

Sex hormones influence the structure and function of the brain, but little is known about the effect of hormone therapies (HT) on changes in the brain during menopause.

10 Jun 2020

GlobalData: Use of hydroxychloroquine as COVID19 treatment continues to be debated

There is no clinical evidence that hydroxychloroquine is effective against COVID19. Some studies using hydroxychloroquine have shown no benefits or even an increase in risk of death, but the number of clinical trials investigating hydroxychloroquine as a primary or secondary intervention continues to expand to determine whether the drug candidate is a key contender as a therapeutic or not, says GlobalData, a leading data and analytics company.

10 Jun 2020

Registered COVID-19 clinical trials lack key features to optimize their scientific value

Most of the registered clinical trials of potential treatments for COVID-19 underway as of late March were designed in ways that will greatly limit their value in understanding potential treatments, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

10 Jun 2020

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

A new study from Lawson Health Research Institute and Western University suggests that fecal transplants could be used as a treatment for non-alcoholic fatty liver disease.

9 Jun 2020

Cannabis temporarily reduces severity of PTSD symptoms

People suffering from post-traumatic distress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by Carrie Cuttler, a Washington State University assistant professor of psychology.

9 Jun 2020

High-salt diet may modulate the gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

9 Jun 2020

Empagliflozin reduces CKD progression in type 2 diabetics with cardiovascular disease

Empagliflozin (EMPA), a selective inhibitor of sodium/glucose cotransporter 2 (SGLT2 inhibitors, "gliflozines"), reduces CKD progression in type 2 diabetics (T2D) with cardiovascular disease, presumably by lowering intraglomerular pressure.

9 Jun 2020

Drug offers hope for patients with primary hyperoxaluria type 1

Primary hyperoxaluria type 1 (PH1) is an autosomal recessive inherited disorder that begins in childhood and adolescence.

8 Jun 2020

Using antibodies to detect Alzheimer’s disease

News-Medical speaks to Professor Vendruscolo about his research that uses antibodies to detect Alzheimer's disease, which could help to improve drug discovery.

8 Jun 2020

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

In 2017 and 2019, the German Institute for Quality and Efficiency in Health Care had already examined the advantages and disadvantages of ribociclib in combination with an aromatase inhibitor or fulvestrant in comparison with the appropriate comparator therapy in patients after menopause, with hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer.

5 Jun 2020

Study shows how psychedelic drug psilocybin works in the brain

Perhaps no region of the brain is more fittingly named than the claustrum, taken from the Latin word for "hidden or shut away."

5 Jun 2020

Placebo News and Research

Novel antisense drug shows promise to improve health of people with NAFLD

Breakthrough drug significantly delays onset of type 1 diabetes, study finds

Experimental drug to prevent deadly blood coagulation in patients with COVID-19

UIC clinical trial to soon test a vaccine for COVID-19

BCG vaccination strengthens the immune system

Hydroxychloroquine shows no antiviral effect on SARS-Cov-2 in non-human primate models

Study initiates hydroxychloroquine clinical trial to prevent COVID-19 in healthy people

Aspirin reduces hereditary colorectal cancer risk

Antihypotensive agent for sepsis disrupts the immune system, increases susceptibility to infections

Age-related structural brain changes are linked to hormone-level changes

GlobalData: Use of hydroxychloroquine as COVID19 treatment continues to be debated

Registered COVID-19 clinical trials lack key features to optimize their scientific value

Fecal transplants could be used as treatment for non-alcoholic fatty liver disease

Cannabis temporarily reduces severity of PTSD symptoms

High-salt diet may modulate the gut microbiome

Empagliflozin reduces CKD progression in type 2 diabetics with cardiovascular disease

Drug offers hope for patients with primary hyperoxaluria type 1

Using antibodies to detect Alzheimer’s disease

Newer data confirms survival advantages, but also side effects for ribociclib in breast cancer

Study shows how psychedelic drug psilocybin works in the brain

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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