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Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

In a recent study, RBD produced in various cell types are characterized in-depth, comparing their applicability for future COVID-19 research.

21 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

A novel FACS-based approach for SARS-CoV-2 serology

A recent study discusses a simple, sensitive, and quantitative serological test based on FACS assay to evaluate antibodies against SARS-CoV-2.

20 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Guinea recently experienced its second outbreak of the Ebola virus disease within the last decade.

19 Sep 2021

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

In a study available on the preprint server medRxiv*, researchers have created a vaccine designed to overcome issues associated with attenuated-virus vaccines.

17 Sep 2021

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

To investigate the immune memory sustainability of SARS-CoV-2-specific B cells and T cells, stimulated by the inactivated vaccine, and the potential need for a third booster dose in healthcare workers (HCWs), a non-randomized trial was undertaken by researchers at Sun Yat-sen University in Guangzhou, China. the research is posted online on the medRxiv* preprint server.

17 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

In the early days of the pandemic, with commercial COVID tests in short supply, Rockefeller's Robert B. Darnell developed an in-house assay to identify positive cases within the Rockefeller community.

16 Sep 2021

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

Researchers in the United States and Germany have conducted a study showing that the Pfizer-BioNTech vaccine designed to protect against coronavirus disease 2019 (COVID-19) is effective against recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).

16 Sep 2021

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Researchers from Simon Fraser University in Canada decided to investigate the magnitude of immunity in mRNA vaccines for COVID-19.

15 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

In a research paper recently uploaded to the medRxiv* preprint server by Capelle et al. (September 2nd, 2021), the immune response of mild and hospitalized COVID-19 patients is compared, finding that early T-cell response is a vital indicator of SARS-CoV-2 disease severity.

15 Sep 2021

Quantification of salivary IgG and IgA against SARS-CoV-2

Salivary antibody levels are many fold lower than found in blood serum, Immunoglobulin G (IgG) in the saliva is mainly sourced from leakage from the gingival surface and Immunoglobulin A (IgA) from mucosal membranes.

15 Sep 2021

Prior symptomatic COVID-19 enhances mRNA vaccine response

A new paper describes the antibody responses in people who have already been infected with SARS-CoV-2 and are vaccinated as compared to the naïve.

14 Sep 2021

Blood serum test can identify which breast cancer patients have slow-growing disease

Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in their blood serum at the start of anti-estrogen treatment live longer and go longer without their disease progressing than patients with high levels.

14 Sep 2021

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Dynamics of healthcare-associated SARS-CoV-2 infections revealed with whole genome sequencing

In a recent paper, the researchers study the dynamics of SARS-CoV-2 infections on a geriatric hospital ward by whole genome sequencing.

13 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Assay News and Research

Researchers seek to identify the role of hypoxia on red blood cell aging

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

A novel FACS-based approach for SARS-CoV-2 serology

T cell immunity induced after mild COVID could contribute to protection against re-infection

Analysis of 2021 Ebola outbreak reveals long-term dormant infections

Adenovirus-based nanoparticle vaccine elicits potent SARS-CoV-2 neutralizing antibody response

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Rockefeller saliva test turns out to be easier and safer to administer than conventional COVID tests

Pfizer-BioNTech’s COVID-19 vaccine proves effective against recent SARS-CoV-2 variants

COVID mRNA vaccines display weakened immune response with age and diminish over time, according to new study

Aptamers for Targeting SARS-CoV-2 Proteins

Deep profiling of SARS-CoV-2 immune response amongst the mildly symptomatic

Quantification of salivary IgG and IgA against SARS-CoV-2

Prior symptomatic COVID-19 enhances mRNA vaccine response

Blood serum test can identify which breast cancer patients have slow-growing disease

Jumpcode Genomics and TGen collaborate on genomic sequencing of SARS-CoV-2

Dynamics of healthcare-associated SARS-CoV-2 infections revealed with whole genome sequencing

New SARS-CoV-2 mechanism of host gene suppression

eBook: Using iPSCs models for human disease research and drug discovery eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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