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Integrated approach addresses some of the biggest challenges in natural products drug discovery

Many successful drugs have their origins in natural sources such as plants, fungi, and bacteria, but screening natural products to identify potential drugs remains a difficult undertaking.

1 Dec 2022

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

Australian researchers unearth a new form of antimicrobial resistance

Australian researchers have uncovered a new form of antimicrobial resistance (AMR) – undetectable using traditional laboratory testing methods – in a discovery set to challenge existing efforts to monitor and tackle one of the world's greatest health threats.

30 Nov 2022

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Researchers assessed the taxonomic characteristics of the intestinal (gut) microbiome in patients with active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

30 Nov 2022

Newly discovered material can aid healing of hard-to-treat diabetic wounds

Scientists have discovered a new material that can be applied to diabetic wounds to heal them faster with just one application.

29 Nov 2022

Envomed appoints Hagai Yehidi as new CEO

Envomed, the brand behind the Envomed80 on-site medical waste treatment solution, has appointed Hagai Yehidi as its new CEO.

From Envomed 29 Nov 2022

Does breast milk influence infants' intestinal microbiota?

A large number of health-related benefits of probiotics have led to the development of a new discipline called probiogenomics, which focuses on the molecular mechanisms of probiotic activities. According to the US Food and Drug Administration (FDA), the next-generation probiotics satisfy the scope of "live biotherapeutic products" (LBPs), which could be used to develop effective therapeutics for various diseases.

28 Nov 2022

How does quinoa affect the gut microbiome of men?

Although a high intake of whole grain foods reduces the risk of cardiometabolic diseases, obesity, type 2 diabetes, and certain types of cancers, the underlying mechanism behind this occurrence is unclear. Whole grain foods tend to be healthier due to their high dietary fiber and phytoconstituents, typically lost during refining.

28 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

How micro(nano)plastics interact with human gut microbiota

In a recent study published in the Microbial Biotechnology journal, researchers explored the health effects of micro(nano)plastics and their degraded products on the gut microbiome.

27 Nov 2022

Scientists develop preclinical model of scrub typhus disease

Scientists have developed an animal model of scrub typhus using outbred CD-1 mice. Using the model, they have characterized host susceptibility to the causative pathogen, disease pathogenesis, and immune responses. The study has been published in the journal PLOS Neglected Tropical Diseases.

27 Nov 2022

Study investigates microbial composition in bat lung tissue

Announcing a new article publication for Zoonoses journal. Bats are the hosts of multiple pathogens, but the microbial composition of their lung tissues remains unknown.

25 Nov 2022

Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine.

25 Nov 2022

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.

24 Nov 2022

Wireless smart bandage promotes faster closure of wounds, enhances skin recovery

Some wounds just won't heal. Infections, diseases like diabetes, and suppressed immune systems often stack up to slow healing.

24 Nov 2022

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

Researchers from the Quadram Institute and the University of East Anglia have uncovered how resistance has helped drive the emergence of dominant strains of Salmonella.

24 Nov 2022

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

As part of World Antimicrobial Resistance Week 2022, News-Medical speaks to Dr. Tomislav Meštrović about his new research discussing the burden of bacterial antimicrobial resistance in the WHO European region, as well as about how we can prevent antimicrobial resistance together.

24 Nov 2022

Study highlights global estimates of mortality related to 33 clinically significant bacterial pathogens

Researchers presented comprehensive global estimates of the mortality burden related to 33 species or genera of bacterial pathogenic organisms causing 11 main infectious syndromes in 2019 using data and methods of the GBD 2019 and the global burden of antimicrobial resistance study conducted in the same year.

24 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

Study finds first direct evidence of AMR bacteria migrating from the gut to the lungs

A new study released today in Nature Communications from the Department of Biology, University of Oxford has found the first direct evidence of antibiotic-resistant bacteria migrating from a patient's gut microbiome to the lungs.

24 Nov 2022

Bacterial News and Research

Integrated approach addresses some of the biggest challenges in natural products drug discovery

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Australian researchers unearth a new form of antimicrobial resistance

Researchers explore gut microbiome dysbiosis in acute COVID-19 infection and recovery

Newly discovered material can aid healing of hard-to-treat diabetic wounds

Envomed appoints Hagai Yehidi as new CEO

Does breast milk influence infants' intestinal microbiota?

How does quinoa affect the gut microbiome of men?

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

How micro(nano)plastics interact with human gut microbiota

Scientists develop preclinical model of scrub typhus disease

Study investigates microbial composition in bat lung tissue

Researchers discover a new function of CRISPR/Cas9 gene scissors

New CRISPR-based tool can snip out faulty genes and replace them with new ones

Wireless smart bandage promotes faster closure of wounds, enhances skin recovery

Researchers discover how phage resistance helps drive the emergence of dominant Salmonella strains

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

Study highlights global estimates of mortality related to 33 clinically significant bacterial pathogens

Exploring synthetic engineering of bacteriophages

Study finds first direct evidence of AMR bacteria migrating from the gut to the lungs

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