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Lancet warns Herceptin breast cancer drug 'over hyped'

The Lancet medical journal which is both influential and well respected, has cast some doubt on the claims that Herceptin was "a cure" for breast cancer and has attacked the hype surrounding the treatment by the Government and the media.

10 Nov 2005

Vaccine for a type of blood cancer - follicular lymphoma

A team of researchers has demonstrated the clinical efficacy and benefits of a vaccine for a type of blood cancer, follicular lymphoma, amongst first time relapse patients. Specialists from two University of Navarre centres – the University Hospital and the Research Centre for Applied Medicine (CIMA) - have worked jointly since 2001 on the research.

9 Nov 2005

Introgen's INGN 241 combined with Celebrex kills breast cancer cells

Introgen Therapeutics, Inc. today reported the publication of preclinical data demonstrating that INGN 241 works synergistically with celecoxib (Celebrex) marketed by Pfizer to inhibit the growth and increase apoptosis (cell death) of breast cancer cells.

8 Nov 2005

First clinical study of FX06 treatment against damage caused by heart attacks

Central to the study is FXO6, a peptide developed and patented by Austro-American company Fibrex Medical. Fibrex will now test the tolerability and pharmacokinetics of FX06 in humans. The peptide reduces inflammatory responses of the heart muscle that can arise after treatment for a myocardial infarction. Tests will begin immediately on the first - healthy - subjects at the Vienna General Hospital.

7 Nov 2005

Study proves the effectiveness of Vfend for the treatment of candidemia

Using Vfend (voriconazole) for the treatment of nonneutropenic patients with candidemia, an often-fatal hospital-acquired bloodstream infection, is as effective as a regimen of two older antifungals and carries fewer serious side effects than that regimen.

7 Nov 2005

Smokeless tobacco products are not necessarily a safe alternative to smoking

According to the U.S. Centers for Disease Control and Prevention, nearly one-fourth of Americans are smokers. That's more than 60 million people who are at increased for lung cancer, the leading cause of cancer-related deaths nationwide.

3 Nov 2005

Expert highlights public health problem posed by colorectal cancer

Colorectal cancer is a significant public health problem for which differing treatment regimes hold different benefits in associated efficacy, safety and tolerability, according to study findings showcased at the 13th European Cancer Conference (ECCO).

3 Nov 2005

Vaccine that targets nicotine rather than the brain's reaction to it

Since smoking became popular in America in the 1930s, lung cancer rates have continued to climb. Today, it is still the leading cause of cancer-related deaths, with totals more than the other five leading cancers combined.

3 Nov 2005

Interferon combined with ribavirin treatment is effective for children with chronic Hepatitis C virus

Nearly half of 118 children with chronic Hepatitis C virus (HCV) treated with a combination of interferon-alpha-2b and an optimized dose of ribavirin achieved sustained viral response, and side effects were generally mild.

3 Nov 2005

Rapid screen-and-treat methods significantly reduce cervical cancer precursor lesions

A new study led by Columbia University Medical Center researchers demonstrates the safety and efficacy of two low-tech diagnostic tools to significantly reduce the prevalence of cervical cancer precursor lesions.

3 Nov 2005

Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

"Screen and treat” cervical cancer programs effective in poorly resourced areas

According to a new study two "screen and treat" cervical cancer prevention programs developed for high-risk women in low-resource settings resulted in a lower prevalence of precancerous cervical lesions and cervical cancer, according to a study in the November 2 issue of JAMA: The Journal of the American Medical Association.

2 Nov 2005

A promising new vaccine against a pre-cancerous cervical virus

Updated data from a study on a promising new vaccine against a pre-cancerous cervical virus shows superior efficacy in preventing cervical pre-cancers and non-invasive cervical cancer

1 Nov 2005

Stereotactic body radiation therapy safe and effective way to treat early stage lung cancer in medically inoperable patients

Lung cancer patients with extenuating health problems may have an alternative to traditional radiation therapy through a lung-sparing procedure pioneered at the Indiana University School of Medicine.

1 Nov 2005

Buccal mucosa may help test for lung cancer

In a new study presented at CHEST 2005, the 71st annual international scientific assembly of the American College of Chest Physicians (ACCP), scientists found that buccal mucosa, or cells scraped from the inner part of the cheek, may contain information that separates patients with lung cancer from high-risk negatives

1 Nov 2005

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Results from the first and only interim analysis of an important trial assessing the potential of Herceptin (trastuzumab) to improve disease-free survival (DFS) in HER-2 positive breast cancer patients after adjuvant chemotherapy, have shown that Herceptin affords a significant survival advantage.

1 Nov 2005

$107.6 million grant for malaria vaccine candidate

In an important step toward developing an effective malaria vaccine, the Bill & Melinda Gates Foundation has announced a $107.6 million grant to the PATH Malaria Vaccine Initiative (MVI) to extend the public-private partnership between MVI and GlaxoSmithKline Biologicals (GSK Bio) to develop GSK Bio's malaria vaccine for children in Africa.

30 Oct 2005

Early detection and improved treatment have contributed almost equally to the substantial decrease in breast cancer

Early detection through screening mammography and improved adjuvant treatment have contributed almost equally to the substantial decrease in breast cancer death rates over the past 10 to 15 years, researchers conclude in an unprecedented effort to parse out the factors that have led to the decline.

27 Oct 2005

FDA panel says approval for new depression drugs needs to be faster

According to a Food and Drug Administration (FDA) advisory panel, drug makers seeking U.S. approval of new drugs to treat major depression should not be required to first provide data on how well they work long-term.

26 Oct 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005