Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Novel tests detect common cancer signals across over 50 types of cancer

Cancer doctors, care providers and payers need to get ready for a major shift in early cancer detection that will affect almost every stage of cancer diagnosis and treatment. New data supporting the accuracy of multi-cancer early detection (MCED) blood testing (1), presented at the ESMO Congress 2022, have major implications for future cancer care provision, said Fabrice André, ESMO 2022 Scientific Co-Chair.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Donor iron deficiency produces no harmful effects on donated blood quality or donor wellbeing

Most of the U.S. blood supply comes from about 5 million altruistic volunteers who donate blood regularly. Frequent blood donation is known to result in iron deficiency in donors, which has led to concerns that the practice may not only diminish the quality of donated blood but also harm blood donors' health and quality of life.

8 Sep 2022

NIH animal study combines Paxlovid with Lagevrio against SARS-CoV-2 Delta

In a recent study posted to the bioRxiv* preprint server, researchers at the U.S National Institutes of Health demonstrated the efficacy of molnupiravir and nirmatrelvir, two oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals in the rhesus macaque model, the closest proxy to humans.

7 Sep 2022

Study provides a comprehensive view of the genomics of all childhood ALL subtypes

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL).

1 Sep 2022

New advice aims to reduce the cardiac side effects of cancer treatment

The first European Society of Cardiology Guideline on cardio-oncology is published online today in European Heart Journal.

26 Aug 2022

New approach using CRISPR can engineer massive quantities of cells for therapeutic applications

A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications.

25 Aug 2022

New clinical trial may establish a standard of care for patients with oligometastatic kidney cancer

Kidney cancer encompasses a wide spectrum and can present with extensive metastases or just a handful. However, today all patients are treated the same. They all receive medication.

19 Aug 2022

UC San Diego Health first to offer new injectable medication to patients with hereditary transthyretin amyloidosis

UC San Diego Health is first in the nation to offer a new injectable medication to patients with nerve damage caused by hereditary transthyretin amyloidosis, a rare disease that can be fatal without management.

18 Aug 2022

New strategies to enhance the survival of children with neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN (MYCN amplified), the primary driver of neuroblastoma and its resistance to therapy.

18 Aug 2022

People with blood-related cancers more likely to experience COVID breakthrough infections

Individuals with blood-related cancers are more likely to experience a COVID-19 infection even after being vaccinated, a University of Kansas Cancer Center study has found.

12 Aug 2022

How does COVID-19 increase clotting risk?

An in-depth review article describing coronavirus disease 2019 (COVID-19)-related coagulopathy has recently been published in the journal Nature Reviews Immunology.

11 Aug 2022

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022

MIT researchers develop an easy-to-use test to predict Covid-19 immunity

Most people in the United States have some degree of immune protection against Covid-19, either from vaccination, infection, or a combination of the two. But, just how much protection does any individual person have?

9 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

5 Aug 2022

Study suggests an approach for promoting more equitable interpersonal treatment

Coaching patients to voice their concerns about their medical care and advocate for themselves can offset physicians' racial bias so it doesn't lead to inferior experiences for Black patients, a University of Michigan-led analysis found.

3 Aug 2022

Researchers investigate the protection against meningococcal infection in hematopoietic stem cell transplant recipients

The team in the Hematology Department at Henri Mondor AP-HP Hospital, coordinated by Dr. Christine Robin, and scientists from the Institut Pasteur (the Invasive Bacterial Infections Unit led by Professor Muhamed-Kheir Taha) recently studied protection against meningococcal infection in patients who had received hematopoietic stem cell transplantation.

29 Jul 2022

AAMDSIF Patient and Family Conference to be held in Memphis

The University of Tennessee Health Science Center is partnering with the Aplastic Anemia & MDS International Foundation (AAMDSIF), along with St. Jude Children's Research Hospital, Regional One Health, and Baptist Memorial Hospital, to hold the AAMDSIF Patient and Family Conference for the first time in Memphis on July 23.

22 Jul 2022

Caregivers for patients with multiple myeloma may suffer from anxiety and depression

Caregivers for patients with multiple myeloma may suffer from higher rates of anxiety and depression than patients themselves, according to a new study published today in Blood Advances.

18 Jul 2022