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Harvard researchers outline roadmap to solve orphan receptor challenge

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.

22 May 2026

Optimized extended PCLS culture system extends tissue viability up to two weeks

Precision-cut liver slice (PCLS) technology has long been regarded as a promising ex vivo platform because it preserves the native multicellular architecture of liver tissue.

22 May 2026

Scientists join international collaborative to advance Parkinson’s disease research

Michael Koob, PhD, and his team from University of Minnesota Medical School have been selected to join the Collaborative Research Network (CRN), an international, multidisciplinary, multi-institutional network working to address high-priority research questions about Parkinson's disease, through a $6 million grant awarded by Aligning Science Across Parkinson's (ASAP), in partnership with The Michael J. Fox Foundation for Parkinson's Research (MJFF).

22 May 2026

New study shows how exercise hormone reduces multiple sclerosis symptoms

A new study offers clues as to why exercise can improve neurological symptoms in people with multiple sclerosis (MS).

21 May 2026

First-of-its-kind pregnancy hormone test reveals why female IBD patients face severe symptom flares

Inflammatory bowel disease (IBD), which comprises the inflammatory conditions Crohn's disease and ulcerative colitis, affects about 1.6 million Americans, many of whom cannot be effectively treated.

21 May 2026

Key neural circuit helps the brain “change gears”

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Researchers track genetic changes in Brazil's rare Sabiá virus

The Sabiá virus causes an acute hemorrhagic and neurological syndrome. Four fatal cases have been recorded in the state of São Paulo since 1990.

20 May 2026

Study paves way for earlier pancreatic cancer diagnoses in patients with low-risk pancreatic cysts

Catching pancreatic cancer early can increase the five-year survival rate from 15% to 80%. Patients with pancreatic cysts, frequently detected during unrelated abdominal CT or MRI imaging, can develop malignant pancreatic cancers.

20 May 2026

Fatty liver disease linked to higher risk of heart attacks

Researchers at Mass General Brigham Heart and Vascular Institute found that people with hepatic steatosis, commonly called "fatty liver disease," have a higher amount of noncalcified, rupture-prone coronary plaque and face nearly twice the rate of cardiovascular events compared to those without steatosis.

20 May 2026

Study links pediatric sedation strategies with later neurocognitive outcomes

A new Penn Nursing study suggests that the specific sedatives used during critical illness in early childhood may have long-term implications for a child's neurocognitive development.

19 May 2026

Researchers identity patients with exceptional tirzepatide response outcomes

Tirzepatide GLP-1 medication is known to improve sleep apnea for people with both obstructive sleep apnea (OSA) and obesity, but not all patients benefit equally.

19 May 2026

Children's mental health concerns increasingly addressed during primary care visits

A new study led by researchers at the Harvard Pilgrim Health Care Institute, Boston University, Boston Medical Center, UMass Chan Medical School, and Brown University finds that children's mental health concerns are appearing more often during routine visits with primary care doctors.

18 May 2026

Sleep complaints highlight Alzheimer's risk in genetically predisposed women

Sleep complaints may be an important Alzheimer's disease risk factor in older women with a higher genetic predisposition to the disease, according to a new study from researchers at the University of California San Diego.

18 May 2026

Surgical training program for community health officers slashes maternal mortality risk

Maternal mortality in Sierra Leone used to be among the highest in the world. A 15-year-old non-profit program that trains community health officers to do life-saving surgeries has helped slash that risk by two-thirds.

18 May 2026

New York City's mold-removal program reduces the burden of asthma exacerbations

The New York City Housing Authority developed Mold Busters, a mold-removal program, in response to a 2013 class-action lawsuit filed by residents suffering from asthma due to mold in their apartments.

18 May 2026

Addressing depression and anxiety in primary care improves chronic pain management

A study published this month in the American Journal of Managed Care explores how integrating behavioral health care into primary care can improve outcomes and be cost-effective for adults with depression, anxiety and chronic pain who are on long-term opioid therapy.

15 May 2026

Identifying the methodology gap that prevents treatment of infection-triggered chronic diseases

Thousands of Americans develop chronic persistent symptoms-such as fatigue, cognitive difficulties ("brain fog"), and other debilitating issues-each year following acute infections from Lyme disease, COVID-19, and other pathogens. Efforts to identify causes and produce treatments have failed. However, 16 leading researchers think they know part of the problem: study design.

14 May 2026

Base editing approach repairs deadly Dravet syndrome mutation in mice

Gene editing can repair a DNA error in mice that causes Dravet syndrome, a rare, incurable, and potentially deadly form of childhood epilepsy. After the edit, the mice have far fewer seizures and live much longer.

13 May 2026

Air pollution linked to rising kidney disease hospitalization risks

A study supported by FAPESP and published in the journal Scientific Reports showed a strong correlation between the concentration of particulate matter in the air of São Paulo, Brazil – primarily emitted by vehicle fuel combustion – and kidney disease.

13 May 2026

Study reveals hidden struggles faced by unaccompanied child refugees

From relentless cycles of intrusive memories to loneliness and physical pain - a new study form the University of East Anglia reveals the struggles of refugees who entered the UK as unaccompanied minors.

13 May 2026