Mitochondria News and Research

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New research extensively explores 12 distinctive aging traits

In a recent article published in Cell, researchers proposed that 12 distinctive traits of aging are all inter-related.

5 Jan 2023

Novel experimental approach slows physical decline and extends the lives of roundworms

Scientists in aging research today report a novel experimental approach that slowed the rate of physical decline and lengthened the lives of roundworms commonly used in biological studies, C. elgans.

30 Dec 2022

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

Myelin influences energy management of inhibitory brain cells

Researchers at the Netherlands Institute for Neuroscience have discovered that the energy management of inhibitory brain cells is different compared to excitatory cells in our brain.

20 Dec 2022

Probiotic bacterium prevents neurodegeneration in animal model of ALS

A probiotic bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm, an animal model used to study amyotrophic lateral sclerosis (ALS).

20 Dec 2022

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this “starvation response” is triggered, and what can inhibit it.

15 Dec 2022

Novel gene mutation linked to rare premature-aging syndrome

UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.

8 Dec 2022

New insights into how the circadian clock influences T cell responses to vaccination

Research by RCSI University of Medicine and Health Sciences has provided new insights into the mechanism behind how our circadian 24-hour body clock influences our immune response to vaccines, depending on the time of day.

5 Dec 2022

Discovery offers an avenue for development of novel therapies for Chagas disease

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects some 8 million people worldwide. More than a third develop severe heart or digestive problems with a heightened risk of death.

5 Dec 2022

Endogenous system may be responsible for delayed onset of diabetic retinopathy

About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop DR for more than 50 years.

29 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022

Mitochondria plays an important role in signal transduction in innate immune pathways

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.

17 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Study reveals a mechanism for mitochondrial activation via nucleoid dynamics

Mitochondria, famously known as the powerhouse of the cell, are important cellular structures that are vital for their role of generating energy. Mitochondria are "dynamic", meaning they constantly fuse together and split apart. They contain a small amount of genetic information known as mitochondrial DNA (mtDNA).

17 Nov 2022

National Institutes of Health funds a five-year, $11 million initiative

The conversations between our bone and muscle change as we age, and both are the weaker for it, Medical College of Georgia scientists say.

17 Nov 2022

SARS-CoV-2 infection triggers reactivation of latent viruses in people with chronic fatigue syndrome

COVID-19 reactivated viruses that had become latent in cells following previous infections, particularly in people with chronic fatigue syndrome, also known as ME/CFS.

16 Nov 2022

Carnitine intake in the first postnatal weeks promotes better growth, larger brain size in very preterm infants

A recent study by the University of Eastern Finland and Kuopio University Hospital shows that carnitine intake in the first postnatal weeks promotes better growth and larger brain size at term equivalent age in very preterm infants.

15 Nov 2022

Metabolomic study of genetic regulation of biochemical individuality

Researchers systematically investigated the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites.

15 Nov 2022

What is the role of macrophage origin, function, and heterogeneity in health and disease?

In a new study, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages.

14 Nov 2022

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

8 Nov 2022

Mitochondria News and Research

New research extensively explores 12 distinctive aging traits

Novel experimental approach slows physical decline and extends the lives of roundworms

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Myelin influences energy management of inhibitory brain cells

Probiotic bacterium prevents neurodegeneration in animal model of ALS

Researchers discover previously unknown mechanism for how 'starvation response' is triggered

Novel gene mutation linked to rare premature-aging syndrome

New insights into how the circadian clock influences T cell responses to vaccination

Discovery offers an avenue for development of novel therapies for Chagas disease

Endogenous system may be responsible for delayed onset of diabetic retinopathy

Previously unknown links between genetic factors in ASD identified

Mitochondria plays an important role in signal transduction in innate immune pathways

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Study reveals a mechanism for mitochondrial activation via nucleoid dynamics

National Institutes of Health funds a five-year, $11 million initiative

SARS-CoV-2 infection triggers reactivation of latent viruses in people with chronic fatigue syndrome

Carnitine intake in the first postnatal weeks promotes better growth, larger brain size in very preterm infants

Metabolomic study of genetic regulation of biochemical individuality

What is the role of macrophage origin, function, and heterogeneity in health and disease?

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

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