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Male and female mice show decreased exploratory behavior with age, study finds

Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.

11 Oct 2019

Study investigates how aging influences fate of fibro-adipogenic progenitors in skeletal muscles

In adult skeletal muscle, loss of myofiber integrity caused by mechanical injuries or diseases are repaired by resident muscle stem cells, called satellite cells, which promptly exit from quiescence after disruption of muscle architecture to expand, differentiate and drive tissue regeneration.

11 Oct 2019

Study shows plastic teabags release micro- and nano-sized particles into tea

Many people are trying to reduce their plastic use, but some tea manufacturers are moving in the opposite direction: replacing traditional paper teabags with plastic ones.

25 Sep 2019

'Clock in a dish' provides new way to replicate developmental disorders

In early mammalian development, timing is everything. For healthy development to occur -- whether it be three weeks for a mouse or nine months for a human -- embryos follow the lead of oscillating genes, which turn on and off in precise cycles and trigger different development milestones. Oscillating genes are conductors keeping time in a symphony of growth.

29 Aug 2019

Researchers identify epigenetic mechanism that may strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine have identified an epigenetic mechanism that appears to strongly influence healthy aging.

9 Aug 2019

NemaMetrix raises $5 million USD funding to expand its Precisome platform

NemaMetrix, an Oregon-based company that provides phenotyping and functional analysis using C. elegans nematodes, today announced it has closed a $5 million USD funding round to expand its Precisome platform: a tool for in vivo testing for early drug discovery, agribio, and precision medicine.

From InVivo Biosystems 30 Jul 2019

Protein Clumps In ALS Neurons Provide Potential Target For New Therapies

Amyotrophic lateral sclerosis is a neurological condition that affects motor neurons -- the nerve cells that control breathing and muscles.

2 Jul 2019

Researchers map full-body muscular activity of Hydra during movement

Accomplishing perhaps a world first, researchers at Columbia University and the Marine Biological Laboratory have mapped the full-body muscular activity of an animal while it was moving and behaving.

25 May 2019

Fruit fly study shows role of unexplored neural circuit in modulating memory strength

Learning to avoid negative experiences requires an interplay of two distinct brain circuits, one to interpret "Yikes!" and drive learning, and the other, unexpectedly, to dial in the strength of that memory, a new fruit fly study shows.

15 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

Science and health journalists awarded Logan Science Journalism Fellowships from MBL

Twelve journalists have been awarded Logan Science Journalism Fellowships from the Marine Biological Laboratory, an international center for biological and environmental research and education and an affiliate of the University of Chicago.

30 Apr 2019

Scientific Symposium at LABVOLUTION focuses on key issues in life sciences

The Scientific Symposium at LABVOLUTION will be focusing on key issues in the life sciences. Accordingly, a high level of visitor demand is anticipated.

From LABVOLUTION 25 Mar 2019

Understanding genetic interactions holds key to new personalized therapies

When the Human Genome Project was completed, in 2003, it opened the door to a radical new idea of health - that of personalized medicine, in which disease risk and appropriate treatment would be gleaned from one's genetic makeup.

25 Mar 2019

Virginia Tech professor uses mathematical modeling simulations to assess vaccine efficacy

The recent measles outbreaks across the country emphasize the importance of vaccinations.

11 Mar 2019

Scientists find clue to rapid human conversations in singing mice

Studying the songs of mice from the cloud forests of Costa Rica, researchers from New York University School of Medicine and The University of Texas at Austin have identified a brain circuit that might enable the high-speed back and forth of human conversation.

1 Mar 2019

Using CRISPR to regulate genes in the rat brain

Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. Described in eNeuro, this technique paves the way for researchers to probe genetic influences on brain health and disease in model organisms that more closely resemble human conditions.

From Society for Neuroscience 25 Feb 2019

Rubicon level linked to inhibition of autophagic process

Autophagy is an important biological recycling mechanism that is used to maintain homeostasis within all types of animal tissue. Many studies have attempted to understand the relationship between the reduction of autophagy and progression of aging in animals; however, none have provided a clear explanation, until now.

20 Feb 2019

New DNA methylation GrimAge tool allows you to predict lifespan and healthspan

The Grim Reaper arrives for each of us eventually--wouldn't it be nice to know when? Now UCLA researchers have developed a new tool to help you plan ahead for your date with the Angel of Death.

13 Feb 2019

Cloning-free Nested CRISPR uses long DNA fragments for efficient gene editing

CRISPR is a technique that is revolutionizing biomedical research through high-precision genome editing. However, even though it allows the creation or correction of mutations consisting of a single or few nucleotides with relative ease, it still possesses limitations upon introducing larger fragments of DNA in the genome.

8 Feb 2019

New 'WormJam model' could provide valuable insights into human aging

What can worms tell us about human aging? A lot more than you'd think; as research led by the Babraham Institute but involving researchers from multiple disciplines drawn together from across the world has shown.

7 Feb 2019