Neurodegenerative Disease News and Research

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Study reveals how air pollution contributes to Alzheimer's disease

Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs.

28 Feb 2025

Retinal changes may serve as early indicator for Alzheimer's disease

A team of scientists at the Indiana University School of Medicine has identified that an eye condition affecting the retina, the light-sensing tissue in the back of the eye, may serve as an early indicator for Alzheimer's disease.

26 Feb 2025

LJI scientists discover a potential new target for treating Parkinson's disease

Scientists at La Jolla Institute for Immunology (LJI) have found a potential new target for treating Parkinson's disease.

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025

Study shows how herpes viruses contribute to Alzheimer's disease in aging brains

Researchers from Cleveland Clinic's Genome Center outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains.

24 Feb 2025

First insights into familial ALS in Egypt reveal genetic variations and disease progression

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle weakness and eventually death.

18 Feb 2025

Human-specific gene variant may hold key to evolution of language

The origins of human language remain mysterious. Are we the only animals truly capable of complex speech? Are Homo sapiens the only hominids who could give detailed directions to a far-off freshwater source or describe the nuanced purples and reds of a dramatic sunset?

18 Feb 2025

Groundbreaking ALS platform trial accelerates research and drug testing

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.

17 Feb 2025

Study reveals brain circuit linked to human creativity

A new study led by researchers at Mass General Brigham suggests that different brain regions activated by creative tasks are part of one common brain circuit.

13 Feb 2025

Researchers discover genetic mutation linked to toxic protein buildup in Alzheimer's

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of the puzzle.

13 Feb 2025

JPND calls for research to improve health and social care for neurodegenerative diseases

The EU Joint Programme - Neurodegenerative Disease Research (JPND) initiative launched a transnational call for health and social care research with a focus on the moderate and late stages of neurodegenerative diseases.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

ASU researchers propose a unifying explanation for molecular chaos driving Alzheimer's disease

In a groundbreaking theory, scientists at Arizona State University's Biodesign Institute propose a unifying explanation for the molecular chaos driving Alzheimer's disease.

6 Feb 2025

Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

Review highlights the role of mitochondrial Ca2+ imbalance in neurodegenerative diseases

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

24 Jan 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

New approach combines two methods to study disordered proteins

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample.

20 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025