Nucleotides News and Research

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SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

A new study shows that the SARS-CoV-2 nucleocapsid protein has unique properties that allow the virus to become more infective in the presence of certain mutations.

11 Feb 2022

Machine learning highly effective at identifying SARS-CoV-2 variants

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9 Feb 2022

Researchers reveal new therapeutic way to block oncogenic RAS mutants

As a 10-year journey comes to fruition, MUSC Hollings Cancer Center researcher John O'Bryan, Ph.D., and colleagues have demonstrated a new therapeutic way to block a protein that is frequently mutated in cancers.

9 Feb 2022

Antarctic soil sample from 2018 adds to the enigma of the COVID-19 pandemic

The origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has long been debated among scientists. However, prior research found early genetic material of a unique SARS-CoV-2 variant from the soil on King George Island, Antarctica between 24 December 2018 and 13th January 2019.

9 Feb 2022

New personalized test to detect leukemia relapse sooner and avoid false negative results

Researchers have developed a new protocol for monitoring acute lymphoblastic leukemia (ALL), the most common cancer in children, to inform more effective treatment strategies and detect disease recurrence.

7 Feb 2022

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

A genetic variant changing just one base pair of nucleotides greatly increases risk of a high-risk subtype of childhood acute lymphoblastic leukemia (ALL), according to a Northwestern Medicine study published in Nature Genetics.

3 Feb 2022

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Researchers investigated the transmission of the SARS-CoV-2 Delta VOC from infected hamsters to humans.

2 Feb 2022

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

In a new study, researchers used a pan-coronavirus PCR to screen bats submitted for rabies testing owing to human exposure in order to find potentially novel bat CoVs that may represent a concern to people.

21 Jan 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic target for lung cancer.

18 Jan 2022

Quantification of SARS-CoV-2 variants in wastewater samples

In a new study, a team of researchers introduced a novel method to estimate the proportion of different SARS-CoV-2 strains in wastewater samples.

17 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Microbial characteristics of COVID-19

To better understand how the disease progresses, a recent paper in the journal Frontiers in Medicine discusses the role of the human microbiota in this condition.

13 Jan 2022

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

To understand and act early and appropriately to emerging variants of concern, researchers have explored the possibility of having a variant-agnostic detection assay.

12 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

Researchers from India have now successfully grown and isolated the Omicron variant from hamsters in vivo with further culturing in the Vero CCL-81 cells in vitro, in a step forward towards testing the effectiveness of existing SARS-CoV-2 vaccines and generation of new Omicron appropriate vaccines.

7 Jan 2022

Nucleotides News and Research

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

Machine learning highly effective at identifying SARS-CoV-2 variants

Researchers reveal new therapeutic way to block oncogenic RAS mutants

Antarctic soil sample from 2018 adds to the enigma of the COVID-19 pandemic

New personalized test to detect leukemia relapse sooner and avoid false negative results

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

Chinese scientists reveal key role of lysosome cell death regulator in lung tumor survival

Quantification of SARS-CoV-2 variants in wastewater samples

Virus-like particles as delivery vehicles for gene-editing

Microbial characteristics of COVID-19

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers isolate Omicron variant, leveling the path to vaccine development and vaccine efficacy studies

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

Transplant recipients benefit from a COVID-19 vaccine booster

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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