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PACs should not be used routinely in patients in intensive care units with severe heart failure

The use of a pulmonary artery catheter (PAC) -- a device used for more than 30 years to assess cardiovascular health and to help guide the treatment of critically ill patients -- does not appear to improve outcomes nor confer added risks to patients.

4 Oct 2005

Students with higher levels of emotional intelligence achieve more academically

The emotional intelligence of students indirectly contributes to academic success in information technology studies, preliminary results from a study led by Virginia Tech researchers show.

4 Oct 2005

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention, according to a study in the October issue of Archives of General Psychiatry.

4 Oct 2005

Substance found in cotton plant could help treat psoriasis

A substance found in the cotton plant could help treat the common skin disease psoriasis, according to new research from the Pharmacy School at Sunderland University launched at the British Pharmaceutical Conference in Manchester.

28 Sep 2005

100 year old technology to fight MRSA

A technique that has been around for more than one hundred years is being used in new research as a way of killing methicillin-resistant Staphylococcus aureus (MRSA) using light. The research to be reported today at the British Pharmaceutical Conference in Manchester, is being undertaken by researchers from Queen's University Belfast.

28 Sep 2005

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Survival of heart attack and unstable angina patients placed on beta-blocker therapy corresponds to specific variations in their genes, according to a study by researchers at Washington University School of Medicine in St. Louis and the Mid America Heart Institute in Kansas City.

27 Sep 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

Innovative new treatment for moderate to severe heart failure

Cardiologists at Beth Israel Medical Center are currently enrolling patients in an investigational study that is looking at the safety and efficacy of an innovative new treatment for moderate to severe heart failure, in which a unique pacemaker-like device helps strengthen the heart's pumping power

26 Sep 2005

CytRx granted "Fast Track" designation for ALS drug

CytRx Corporation today announced that the U.S. Food and Drug Administration (FDA) has granted "Fast Track" designation for the company's leading drug candidate arimoclomol for the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

26 Sep 2005

New treatment option for chronic sinusitis

Acclarent on Saturday unveiled their new treatment option for chronic sinusitis, the Balloon Sinuplasty procedure. Results from the initial safety and feasibility study of this unique, catheter-based treatment for chronic sinusitis were presented by William Bolger, MD, FACS.

26 Sep 2005

Microchip system aims to reduce the number of animals used in the development of new drugs

Reducing the number of animals used in the development of new drugs is a priority for the pharmaceutical industry

26 Sep 2005

Clinical trial participants may not be as unrepresentative of general clinical populations as often reported

It is often suggested that the results of clinical trials are affected by the fact that the patients who volunteer for a trial are more likely to take their medication effectively than those in standard care. This supposition is, however, strongly refuted in the results of a new study revealed at the British Pharmaceutical Conference in Manchester.

26 Sep 2005

Magnetic shoe insoles did not effectively relieve foot pain

...researchers report in the current issue of Mayo Clinic Proceedings. And the results indicate that patients who strongly believed in magnets had pain relief even if they were given false magnets to wear.

26 Sep 2005

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

Effects of 10 commonly prescribed second-generation antidepressants studied

Because clinical depression is so disabling and affects more than 16 percent of adults in the United States at some time in their lives, researchers have worked hard to develop more effective treatments. But how much better are the newer pharmaceuticals?

21 Sep 2005

New study details side effects of five medications that are currently used to treat people with schizophrenia

A large study funded by NIH's National Institute of Mental Health (NIMH) provides, for the first time, detailed information comparing the effectiveness and side effects of five medications - both new and older medications - that are currently used to treat people with schizophrenia.

21 Sep 2005

Dual association of beta-carotene with risk of tobacco-related cancers

A new study of French women has found that high beta-carotene intake--through a combination of diet or supplementation--is associated with a higher risk of tobacco-related cancers in smokers, but the risk of these cancers decreases with increasing beta-carotene intake in nonsmokers.

20 Sep 2005

Women with atrial fibrillation face a higher risk of ischemic stroke than men

Women with atrial fibrillation who are not on anticoagulant therapy have a higher rate of ischemic stroke and face a higher absolute risk for stroke than do men with the condition, according to a joint study

19 Sep 2005

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

The findings are important because coronary artery disease patients can see a significant benefit with a successful procedure. The resulting weight loss is also followed by an improvement in blood pressure, cholesterol, blood sugar and sleep apnea, all factors linked to coronary artery disease.

12 Sep 2005

Efficacy News and Research

PACs should not be used routinely in patients in intensive care units with severe heart failure

Students with higher levels of emotional intelligence achieve more academically

Evaluation of the efficacy of buprenorphine hydrochloride and clonidine hydrochloride, in detoxification of opioid-dependent teenagers

Substance found in cotton plant could help treat psoriasis

100 year old technology to fight MRSA

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

Innovative new treatment for moderate to severe heart failure

CytRx granted "Fast Track" designation for ALS drug

New treatment option for chronic sinusitis

Microchip system aims to reduce the number of animals used in the development of new drugs

Clinical trial participants may not be as unrepresentative of general clinical populations as often reported

Magnetic shoe insoles did not effectively relieve foot pain

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Effects of 10 commonly prescribed second-generation antidepressants studied

New study details side effects of five medications that are currently used to treat people with schizophrenia

Dual association of beta-carotene with risk of tobacco-related cancers

Women with atrial fibrillation face a higher risk of ischemic stroke than men

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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