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Scientists have developed a new dye that could offer noninvasive early diagnosis of Alzheimer's disease

MIT scientists have developed a new dye that could offer noninvasive early diagnosis of Alzheimer's disease, a discovery that could aid in monitoring the progression of the disease and in studying the efficacy of new treatments to stop it.

26 Aug 2005

Depression survey reveals gap in awareness of treatment goals

Results of a new national survey reveal a disparity between what people with depression say they know about their illness and how they manage it.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Lorus identifies novel class of lead drug candidates from small molecule anticancer program

Lorus Therapeutics has announced the continued success in the development of its small molecule anticancer program with the selection of a sub-class of lead molecules from the Company's small molecule program.

24 Aug 2005

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

The use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods, and is associated with several potentially life-threatening adverse events, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

Because of the very high costs in developing drugs for rare genetic diseases, and the low return on investment, the pharmaceutical industry has rarely developed specific treatments for many of these diseases.

23 Aug 2005

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

In five randomized controlled trials involving 457 people, the authors report that for patients treated with methotrexate, as a single therapy or in combination with other drug treatment, pooled data showed a tendency toward an increased risk of death or liver transplantation. The brand names for methotrexate are Rheumatrex and Trexall.

23 Aug 2005

Dietary supplement chitosan shows some promise in treating obesity

The dietary supplement chitosan shows some promise in treating overweight and obesity but has not been shown conclusively to be an effective weight loss aid, according to a new systematic review of current evidence.

23 Aug 2005

Best treatment for the immobilizing trauma of spinal cord compression in metastatic cancer

In this week's Lancet, Patchell's UK research team evaluate traditional surgical and radiation therapy options and conclude that direct decompressive surgery plus postoperative radiotherapy is more effective than either radiotherapy alone or other surgical options.

22 Aug 2005

Novel vaccine strain with high efficacy against tuberculosis

Tuberculosis remains a major global health threat. Although more than 3 billion doses of the BCG vaccine have been administered to fight tuberculosis, the ability of the BCG vaccine to protect adults is very limited, as is its efficacy against newly emerging isolates.

22 Aug 2005

New method to predict protein separation behavior directly from protein structure

Applying math and computers to the drug-discovery process, researchers at Rensselaer Polytechnic Institute have developed a method to predict protein separation behavior directly from protein structure.

22 Aug 2005

Poorer countries to benefit from reinstatement of 7 generic AIDS drugs to WHO's list

India's Ranbaxy Laboratories, seven anti- AIDS drugs, have been added to World Health Organisation's (WHO) prequalification list for use in poor countries.

21 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Pfizer acquires antibody discovery company Bioren

Pfizer and Bioren today announced the completion of a transaction in which Pfizer purchased all outstanding stock of Bioren for an undisclosed amount.

15 Aug 2005

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Postmenopausal women who took a bone-building drug for one year followed by a year on a standard drug that fights bone loss experienced greater increases in bone density than has been reported from any other drug regimen, an NIH-sponsored study has found. Bone density is the standard predictor of fracture risk associated with osteoporosis.

11 Aug 2005

Researchers discover that tumors secrete fatty acids which inhibit the cytotoxic T lymphocytes' ability to kill tumor cells

Researchers have discovered that tumors release fatty acids that interfere with the cells that are trying to kill them. Consequently, strategies that reduce the amount of fatty acids surrounding the tumors may give a boost to anti-cancer therapeutics.

11 Aug 2005

Wet combing four times more effective than chemical treatments for head lice

Fine combing of wet hair is far more effective than current over the counter chemical treatments for eliminating head lice, shows research published online by the British Medical Journal (BMJ) today.

4 Aug 2005

Australian researchers have found a toxin that plays an important role in the progression of Alzheimer's disease

The research, which is led by two University of New South Wales academics, is significant because drugs that are in the advanced developmental phase for other conditions might be able to be used on Alzheimer's patients, to halt the disease progressing.

4 Aug 2005

By not implementing a neuroblastoma screening program the United States and Canada saved $574.1 million in health costs

By not implementing a neuroblastoma screening program between 1989 and 2002, the United States and Canada saved $574.1 million in health costs, avoided the unnecessary treatment of more than 9,200 children, and avoided false-positive findings in more than 5,000 children, according to a new study in the August 3 issue of the Journal of the National Cancer Institute.

2 Aug 2005

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Amphetamines, including the drug popularly known as Ecstasy, can reverse the symptoms of Parkinson's disease in mice with an acute form of the condition, according to new research at Duke University Medical Center.

2 Aug 2005

Efficacy News and Research

Scientists have developed a new dye that could offer noninvasive early diagnosis of Alzheimer's disease

Depression survey reveals gap in awareness of treatment goals

New drug that selectively blocks immune responses protects kidneys after transplant

Lorus identifies novel class of lead drug candidates from small molecule anticancer program

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

Patients with primary biliary cirrhosis who are treated with methotrexate have an increased risk of death

Dietary supplement chitosan shows some promise in treating obesity

Best treatment for the immobilizing trauma of spinal cord compression in metastatic cancer

Novel vaccine strain with high efficacy against tuberculosis

New method to predict protein separation behavior directly from protein structure

Poorer countries to benefit from reinstatement of 7 generic AIDS drugs to WHO's list

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Pfizer acquires antibody discovery company Bioren

Taking parathyroid hormone followed by a year on alendronate shows strong osteoporosis benefit

Researchers discover that tumors secrete fatty acids which inhibit the cytotoxic T lymphocytes' ability to kill tumor cells

Wet combing four times more effective than chemical treatments for head lice

Australian researchers have found a toxin that plays an important role in the progression of Alzheimer's disease

By not implementing a neuroblastoma screening program the United States and Canada saved $574.1 million in health costs

Drugs with similar chemical attributes as Ecstasy might offer useful alternatives to current therapies for Parkinson's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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