Protein C News and Research

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Yale study identifies molecular mechanism behind some lissencephaly disorders

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds.

2 Jan 2025

Discovery of nuclear speckles may improve cancer treatment decisions

Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why.

2 Jan 2025

New protein offers hope for heart regeneration

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish.

2 Jan 2025

Study uncovers aspartate's surprising role in lung metastases

Researchers from the lab of Prof. Sarah-Maria Fendt (VIB-KU Leuven) and colleagues have uncovered that the availability of the amino acid aspartate is one reason why the lung is a frequent organ of metastasis.

1 Jan 2025

Plant-based diets made easier for seniors with innovative tech

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1 Jan 2025

Lithocholic acid enhances health and lifespan, mimicking calorie restriction

Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose tolerance, and lifespan in aged organisms.

1 Jan 2025

Immunocompromised adults show weaker response to RSV vaccines

Johns Hopkins Medicine researchers have shown that people 60 years or older with weakened immunity - primarily organ transplant recipients who take immunosuppressive medications to reduce the risk of rejection and others with immune system disorders - do not respond as strongly to vaccines against the respiratory syncytial virus (RSV) as people in the same age group with normal immune function.

30 Dec 2024

Exploring new ways to improve treatment options for kidney cancer patients

A Medical University of South Carolina Hollings Cancer Center researcher is exploring new ways to improve treatment options for kidney cancer patients.

30 Dec 2024

Rethinking the role of microbiome in age-related bone loss

Osteoporosis is a major health concern worldwide, particularly in aging populations. Despite pharmacological advancements, challenges like side effects, costs, and limited accessibility reduce adherence to treatments.

30 Dec 2024

Novel tool holds great promise for studying mitochondrial calcium signaling

Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations.

27 Dec 2024

Mapping cerebellar nuclei outputs in an autism mouse model

The cerebellum plays a critical role in both motor and non-motor functions, and its dysfunction is linked to various mental disorders, including autism.

27 Dec 2024

Ozone therapy shows promise in treating sepsis-induced lung injury

Sepsis, a severe and often fatal complication of infection, is a leading cause of both ALI and acute respiratory distress syndrome (ARDS).

27 Dec 2024

Setd2 catalytic activity is crucial for embryonic development in mice

A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice.

27 Dec 2024

New strategy revolutionizes glycoproteomics research

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

26 Dec 2024

Complex interactions between nucleic acid sensors and enzymes in immune cells explained

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to nucleic acids, according to a recent study.

26 Dec 2024

Fruit flies steal bacterial defense to survive parasitic wasps

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

24 Dec 2024

WHO TAG-CO-VAC reviews COVID-19 vaccine effectiveness and antigen composition

The WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) continues to closely monitor the genetic and antigenic evolution of SARS-CoV-2 variants, immune responses to SARS-CoV-2 infection and COVID-19 vaccination, and the performance of COVID-19 vaccines against circulating variants.

24 Dec 2024

SPLICER shows promise in Alzheimer's and other diseases

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

23 Dec 2024

New Optimer contract to develop bioanalytical tools for RNA therapy

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, today announces the signing of a new development contract with a rare disease biopharmaceutical company.

From Aptamer Group 23 Dec 2024

Groundbreaking brain atlas sheds light on neural pathways for movement

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination.

23 Dec 2024