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Novel mathematical method may help reduce development of antibiotic-resistant bacteria

It is estimated that each year in the United States 2 million people become infected with bacteria that are resistant to one or more types of antibiotics, and at least 23,000 people will die because of these infections. This problem is being exacerbated by overuse of antibiotics for livestock and also in community clinical practice. This overuse, combined with the slow pace of novel drug discovery is a growing threat to public health.

12 Oct 2015

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Accelerated partial breast irradiation was designed to be a faster, more convenient, and potentially safer way for many women with breast cancer to reduce their mortality risk and help keep their cancer from returning after surgery. But a new study shows that the availability of the approach is failing to reduce the percentage of early-stage breast cancer patients who do not receive the radiation treatment that could save their lives.

12 Oct 2015

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Scientists are now better able to predict how quickly the HIV virus will return after individuals stop treatment following a discovery by researchers at UNSW Australia and the University of Oxford.

12 Oct 2015

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Three phase III studies being presented at the European Committee for Treatment Research in Multiple Sclerosis congress demonstrate that treating MS with ocrelizumab reduces relapse rate and delay onset of disability progression compared to interferon beta-1a in relapsing forms of MS and disability progression in primary progressive MS compared to placebo.

12 Oct 2015

Study looks at survival benefits of surgical resection for melanoma patients with abdominal metastases

Patients with metastatic melanoma who undergo surgery to remove lesions that have spread into the abdomen live more than twice as long as those treated with drug therapy alone, according to novel new research by a North Shore-LIJ Health System cancer surgeon.

12 Oct 2015

Fraunhofer researchers developing new system for rapid analysis of urinary stones

Kidney stones rank among the most common illnesses. Their recurrence might be prevented with the right postoperative care. However, for this to be effective, composition of the stones should be known. Fraunhofer researchers are developing a system for rapid analysis of urinary stones immediately after the surgical procedure.

12 Oct 2015

FDA approves Opdivo to treat patients with advanced non-small cell lung cancer

The U.S. Food and Drug Administration today approved Opdivo (nivolumab) to treat patients with advanced (metastatic) non-small cell lung cancer whose disease progressed during or after platinum-based chemotherapy.

11 Oct 2015

FDA awards research grants to boost product development for patients with rare diseases

The U.S. Food and Drug Administration today announced it has awarded 18 new research grants totaling more than $19 million to boost the development of products for patients with rare diseases, which affect the lives of nearly 30 million Americans.

11 Oct 2015

FDA approves Lonsurf drug for patients with advanced form of colorectal cancer

The U.S. Food and Drug Administration today approved Lonsurf (a pill that combines two drugs, trifluridine and tipiracil) for patients with an advanced form of colorectal cancer who are no longer responding to other therapies.

9 Oct 2015

FDA approves expanded indication for Optune device for brain cancer patients

The U.S. Food and Drug Administration today approved an expanded indication for the Optune device to treat patients with newly-diagnosed glioblastoma multiforme (GBM), an aggressive form of brain cancer.

9 Oct 2015

Gene therapy prevents neuronal death, disease effects in experimental model of PD

An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of PD patients develop progressive disease showing signs of dementia similar to Alzheimer's disease.

9 Oct 2015

IASLC commends pembrolizumab drug approval for cutting-edge lung cancer treatment

The International Association for the Study of Lung Cancer (IASLC) says the move by the U.S. Food and Drug Administration (FDA) to grant accelerated approval for a cutting-edge lung cancer treatment is a positive step forward that may help many patients improve their survival.

9 Oct 2015

Xuriden (uridine triacetate) now approved for patients with hereditary orotic aciduria

Today, the U.S. Food and Drug Administration approved Xuriden (uridine triacetate), the first FDA-approved treatment for patients with hereditary orotic aciduria. Hereditary orotic aciduria is a rare metabolic disorder, which has been reported in approximately 20 patients worldwide.

9 Oct 2015

FDA approves Promacta to treat pediatric patients with chronic immune thrombocytopenic purpura

The U.S. Food and Drug Administration today approved Promacta (eltrombopag) to treat low blood platelet count in pediatric patients – ages one year and older – with a rare blood disorder called chronic immune thrombocytopenic purpura (ITP). Promacta can be used in these children when they have not achieved an appropriate response using other ITP medicines or surgery to remove the spleen.

9 Oct 2015

Researchers reveal new subtypes of invasive lobular carcinoma

Researchers from the UNC Lineberger Comprehensive Cancer Center and other academic centers have revealed new subtypes of invasive lobular carcinoma, the second most commonly diagnosed invasive breast cancer type. The findings could lead to personalized treatment approaches for the disease.

9 Oct 2015

Study confirms neuroprotective effects of hypothermia in newborns with HIE

A unique study at Children's Hospital Los Angeles of newborns treated with hypothermia for hypoxic-ischemic encephalopathy (HIE) - a condition that occurs when the brain is deprived of an adequate oxygen supply - confirms its neuroprotective effects on the brain.

9 Oct 2015

Varubi (rolapitant) approved to prevent delayed phase chemotherapy-induced nausea and vomiting

The U.S. Food and Drug Administration approved Varubi (rolapitant) to prevent delayed phase chemotherapy-induced nausea and vomiting (emesis). Varubi is approved in adults in combination with other drugs (antiemetic agents) that prevent nausea and vomiting associated with initial and repeat courses of vomit-inducing (emetogenic and highly emetogenic) cancer chemotherapy.

9 Oct 2015

Repatha (evolocumab) injection gets FDA approval for high cholesterol

The U.S. Food and Drug Administration today approved Repatha (evolocumab) injection for some patients who are unable to get their low-density lipoprotein (LDL) cholesterol under control with current treatment options.

9 Oct 2015

Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

Women, and especially younger women, are much less likely than men to have good relief of chronic, non-cancer pain with long-term opioid use, with only one in five women reporting low levels of pain and high levels of function with chronic opioid therapy in a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

9 Oct 2015

People with restless legs syndrome at higher risk for stroke, heart and kidney disease

Imagine trying to lie down and rest but feeling an uncontrollable urge to keep moving your legs. That, in a nutshell, is the ongoing ordeal facing people with restless legs syndrome. Considered a neurological, sleep, or movement disorder, RLS affects up to 1 in 10 people in the U.S. For those coping with a more severe form of RLS, countless sleepless nights--during which they may toss and turn constantly, or get up and pace the floor--can shatter quality of life.

9 Oct 2015

Therapy News and Research

Novel mathematical method may help reduce development of antibiotic-resistant bacteria

Many early-stage breast cancer patients still not getting life-saving treatment, new study finds

Discovery may help scientists to better predict how quickly HIV virus returns after patients stop treatment

Phase III studies show Roche's ocrelizumab reduces relapse rate, delays disability progression in MS patients

Study looks at survival benefits of surgical resection for melanoma patients with abdominal metastases

Fraunhofer researchers developing new system for rapid analysis of urinary stones

FDA approves Opdivo to treat patients with advanced non-small cell lung cancer

FDA awards research grants to boost product development for patients with rare diseases

FDA approves Lonsurf drug for patients with advanced form of colorectal cancer

FDA approves expanded indication for Optune device for brain cancer patients

Gene therapy prevents neuronal death, disease effects in experimental model of PD

IASLC commends pembrolizumab drug approval for cutting-edge lung cancer treatment

Xuriden (uridine triacetate) now approved for patients with hereditary orotic aciduria

FDA approves Promacta to treat pediatric patients with chronic immune thrombocytopenic purpura

Researchers reveal new subtypes of invasive lobular carcinoma

Study confirms neuroprotective effects of hypothermia in newborns with HIE

Varubi (rolapitant) approved to prevent delayed phase chemotherapy-induced nausea and vomiting

Repatha (evolocumab) injection gets FDA approval for high cholesterol

Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

People with restless legs syndrome at higher risk for stroke, heart and kidney disease

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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