Efficacy News and Research

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Investigational drug may help prevent recurrence of ovarian cancer

A drug that may help prevent recurrence of ovarian cancer by inhibiting development of new blood vessels essential to cancer growth is under study at the Medical College of Georgia.

9 Mar 2005

Lipitor patients who reduced 'bad' cholesterol show decrease in heart attack and stroke

Patients with coronary heart disease who took Pfizer's cholesterol-lowering medicine Lipitor (atorvastatin calcium) and lowered their cholesterol to well below recommended levels experienced significantly fewer heart attacks and strokes than those who only lowered their cholesterol to recommended levels

8 Mar 2005

Use of herbal supplements in women is increasing

The use of herbal supplements in women is increasing. Many mothers may also be giving herbal supplements to their children to treat or prevent various illnesses, including asthma, hyperactivity, colds, and respiratory infections.

8 Mar 2005

Revlimid results look promising for multiple myeloma patients

The Multiple Myeloma Research Foundation (MMRF) applauded today's Celgene announcement regarding Revlimid, a new class of novel immunomodulatory drugs currently being evaluated to treat a broad range of hematology and oncology conditions, including multiple myeloma.

8 Mar 2005

Drug eluting stents as effective as vascular brachytherapy in preventing restenosis

After angioplasty is performed to widen clogged arteries, surgeons frequently use tiny wire-mesh tubes called stents to keep blood vessels open. But despite stenting, scar tissue can form to create new blockages -- a process called in-stent restenosis (ISR).

7 Mar 2005

Use of cilostazol, clopidogrel and aspirin results in a significant reduction of thrombotic complications in the prevention of heart attacks

Three drugs, each of which works in a different way, are used in anti-platelet therapy to help prevent restenosis (the reclogging of blood vessels after they have been cleared with percutaneous coronary intervention or PCI) or thrombosis (obstruction of an artery or vein by a blood clot).

7 Mar 2005

Battle in the Senate over FDA

In the congressional battle over the safety of America's prescription drugs, two University of Washington experts with opposing views have been enlisted into the fray.

7 Mar 2005

Stent trial fails to meet endpoints

Angiotech Pharmaceuticals has announced that results from the REALITY Trial, a head-to-head trial sponsored by Cordis Corporation, comparing the JNJ CYPHER® stent and the TAXUS® stent, were presented at the American College of Cardiology Annual Scientific Session. The trial failed to meet its primary endpoint.

7 Mar 2005

Neuren and Metabolic collaborate to develop range of nerve repair compounds

Neuren Pharmaceuticals Ltd (Neuren) and Metabolic Pharmaceuticals Ltd (Metabolic) have announced that the two companies have agreed to collaborate to co-develop Neuren's class of Neuro-regenerative Peptides (NRPs) for the treatment of degenerative conditions such as peripheral neuropathy, motor neuron disease and repairing the brain or nerves after injuries such as spinal cord injury.

7 Mar 2005

HAART saves 2 million life years

The total impact of HIV treatment in the US has been evaluated for the first time. Dr. Rochelle Walensky, ( Harvard Medical School in Boston), speaking at the 12th Annual Retrovirus Conference, quoted from research which estimated the survival benefits of highly active antiretroviral therapy (HAART) and opportunistic infection prophylaxis in the US from 1989 to 2003.

2 Mar 2005

Comprehensive sex education is more effective at stopping the spread of HIV infection

It is estimated that more than half of all new HIV infections occur before the age of 25 and most are acquired through unprotected sexual intercourse.

28 Feb 2005

New technologies may offer new treatment options for some patients with degenerative back problems

New technologies may offer new treatment options for some patients with degenerative back problems, according to research presented at the 72nd Annual Meeting of the American Academy of Orthopaedic Surgeons. These latest innovations in spinal surgery could provide promise for hundreds of thousands of U.S. patients who undergo spinal surgery each year.

27 Feb 2005

New compounds for the treatment of HIV/AIDS

Scientists from Tibotec Pharmaceuticals Ltd. presented data on several new compounds for the treatment of HIV/AIDS at the 12th Conference on Retroviruses and Opportunistic Infections (CROI), held February 22-25 in Boston, MA, USA.

27 Feb 2005

Gel provides protection from HIV and herpes

Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina.

27 Feb 2005

Proof that vaccinating children against influenza in the hope of reducing disease spread is inconclusive

Proof that vaccinating children aged 6 to 24 months against influenza in the hope of reducing disease spread is inconclusive. These conclusions are based on a small number of studies based on a large dataset of reasonable quality.

27 Feb 2005

Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005

Benitec announces AIDS collaboration

Benitec today announced a collaboration with City of Hope (based in Duarte California) to develop a novel T-cell based therapy for AIDS patients.

22 Feb 2005

Diagnosis of prions in patients should utilize novel strategy, conformation-dependent immunoassay

A technique for detecting prions in tissue, developed in recent years by UCSF scientists, is significantly more sensitive than the diagnostic procedures currently used to detect the lethal particles in samples of brain tissue from patients, according to a study performed by a UCSF team.

22 Feb 2005

Three-day antibiotic treatment for treating bladder infections in women

A three-day regimen of the antibiotic amoxicillin-clavulanate is not as effective as ciprofloxacin at treating an uncomplicated bladder infection in women, according to a study conducted by Thomas M. Hooton, M.D., of the University of Washington and Harborview Medical Center, Seattle, and colleagues.

21 Feb 2005

Biochemical marker aids prognosis in liver transplant patients

A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

20 Feb 2005