Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

G6PD enzyme offers a promising therapeutic target in autoimmune diseases

A team from the University of Valencia, the La Fe Hospital Health Research Institute, and the INCLIVA Institute have participated in the identification of an enzyme (G6PD) as a possible therapeutic target in autoimmune diseases or in controlling exacerbated inflammatory responses such as the one caused by SARS-CoV-2 infection.

25 Jun 2020

Increase in sedentary behavior can contribute to cardiovascular health deterioration

The adverse side effects of the social isolation measures implemented to combat COVID-19 include an increase in sedentary behavior and physical inactivity, which can contribute to a deterioration in cardiovascular health even in the short term. Older people and people with chronic diseases tend to be most affected.

24 Jun 2020

Statin therapy linked to lower death rate in hospitalized patients with COVID-19

The use of cholesterol-lowering drugs called statins is associated with a lower death rate and a lower incidence of mechanical ventilation in patients hospitalized with Coronavirus disease 2019 (COVID-19), researchers report June 24 in Cell Metabolism.

24 Jun 2020

Long-term endurance training alters the activity of genes involved in metabolic health

Decades-long endurance training alters the activity of genes in human skeletal muscle that are important for metabolic health.

23 Jun 2020

Research shows females use anti-inflammatory T cells to maintain their blood pressure

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.

23 Jun 2020

Unexpected discovery helps explain fundamental mystery about how muscles work

Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its energy needs, and adapt to exercise.

21 Jun 2020

Researchers discover mechanical cause for cell extrusion

The outer or inner boundaries of organs in the human body are lined with so-called epithelial sheets. These are layers of epithelial cells that can individually change their 3D shape -- which is what happens during biological processes like organ development (morphogenesis), physiological equilibrium (homeostatis) or cancer formation (carcinogenesis).

19 Jun 2020

SFU study could help improve quality of life for seniors in long-term care

Simon Fraser University researchers are hoping their latest study on seniors will help to address one of their biggest physical challenges -- injury from falls.

17 Jun 2020

Exercise has profound protective effect in mouse models of Friedreich's ataxia

A top exercise researcher at the University of Virginia School of Medicine is urging clinical trials of exercise in patients with Friedreich's ataxia after finding that physical activity has a "profound" protective effect in mouse models of the debilitating genetic disease.

16 Jun 2020

First National Preclinical Imaging Centre established in Ireland to enhance medical research

A new National Preclinical Imaging Centre which will provide enhanced research data to inform new clinical trials that aim to improve patient outcomes, has been awarded funding of €3.4 million under the Science Foundation Ireland Research Infrastructure Programme.

16 Jun 2020

Creating the first 3D neural map of a heart

News-Medical spoke to Dr. Vadigepalli and Dr. Schwaber about their groundbreaking research in which they managed to map the neurons in the heart.

15 Jun 2020

Study reveals protein responsible for vulnerability in cancer cells

A new University of California, Irvine-led study reveals a protein responsible for genetic changes resulting in a variety of cancers, may also be the key to more effective, targeted cancer therapy.

14 Jun 2020

Inhibitory interneurons cause excitation in the developing brain

Brain function depends on inhibitory cells that balance or 'brake' excitation. These neurons allow the brain to process information and also prevent runaway seizures.

12 Jun 2020

Interferons being tested for COVID-19 may increase susceptibility to bacterial infections

Two separate studies in mice suggest that a class of interferons being evaluated in clinical trials as a therapy for COVID-19 may increase susceptibility to bacterial infections, depending on how long patients are exposed to it, and when they receive it.

12 Jun 2020

Treatment with vitamin A analog improves visual function in diabetic mice

Diabetic retinopathy is a common complication of diabetes and a leading cause of blindness among the working-age population.

11 Jun 2020

Fish oil may be an effective treatment for depression, study shows

A study published in Molecular Psychiatry shows that patient-derived adult stem cells can be used to model major depressive disorder and test how a patient may respond to medication.

11 Jun 2020

College students are sleeping better during COVID-19 stay-at-home orders

The COVID-19 pandemic and resulting stay-at-home orders have taken a toll on many facets of physical and mental health in recent months. But according to new University of Colorado Boulder research, one silver lining may exist.

11 Jun 2020

Researchers identify two brain phenomena that may explain the side-effects of ketamine

Researchers have identified two brain phenomena that may explain some of the side-effects of ketamine.

11 Jun 2020

Examining dopamine receptors in their natural environment

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

Baboon could prove to be a relevant model to test Alzheimer's disease interventions

Scientists at Texas Biomedical Research Institute's Southwest National Primate Research Center recently published findings indicating the baboon could prove to be a relevant model to test therapeutics and interventions for neurodegenerative diseases, such as early stage Alzheimer's and related dementias.

10 Jun 2020

Physiology News and Research

G6PD enzyme offers a promising therapeutic target in autoimmune diseases

Increase in sedentary behavior can contribute to cardiovascular health deterioration

Statin therapy linked to lower death rate in hospitalized patients with COVID-19

Long-term endurance training alters the activity of genes involved in metabolic health

Research shows females use anti-inflammatory T cells to maintain their blood pressure

Unexpected discovery helps explain fundamental mystery about how muscles work

Researchers discover mechanical cause for cell extrusion

SFU study could help improve quality of life for seniors in long-term care

Exercise has profound protective effect in mouse models of Friedreich's ataxia

First National Preclinical Imaging Centre established in Ireland to enhance medical research

Creating the first 3D neural map of a heart

Study reveals protein responsible for vulnerability in cancer cells

Inhibitory interneurons cause excitation in the developing brain

Interferons being tested for COVID-19 may increase susceptibility to bacterial infections

Treatment with vitamin A analog improves visual function in diabetic mice

Fish oil may be an effective treatment for depression, study shows

College students are sleeping better during COVID-19 stay-at-home orders

Researchers identify two brain phenomena that may explain the side-effects of ketamine

Examining dopamine receptors in their natural environment

Baboon could prove to be a relevant model to test Alzheimer's disease interventions

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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