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New compounds from fungi show promise in treating colorectal cancer

Novel chemical compounds from a fungus could provide new perspectives for treating colorectal cancer, one of the most common and deadliest cancers worldwide.

17 Oct 2024

Gum disease tied to higher thrombosis risk: Could periodontal therapy help save lives?

The connection between gum disease and thrombosis underscores the role of oral health in reducing thrombotic disease risk and improving patient outcomes.

17 Oct 2024

Pediatric brain tumor research takes leap forward with CBTN data

The Gabriella Miller Kids First Data Resource Center (Kids First DRC) announces the addition of the full Children's Brain Tumor Network (CBTN) dataset to the Kids First DRC portal. This significant milestone provides researchers worldwide with unprecedented access to a vast repository of pediatric brain tumor data, paving the way for groundbreaking discoveries and accelerating the development of innovative treatments.

17 Oct 2024

Microplastics accelerate aging and inflammation in fat tissue, increasing risk of chronic disease

Researchers investigate the effects of microplastic exposure on the normal aging and function of adipose tissue.

16 Oct 2024

FDA-approved breast cancer drug shows promise for appendix cancer

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

16 Oct 2024

Molecular chaperones as key players in tumor suppressor stability

A new review was published in Oncotarget's Volume 15 on October 1, 2024, entitled, "Molecular chaperones: Guardians of tumor suppressor stability and function."

16 Oct 2024

Enhancing mRNA lifespan: A step forward in therapeutic development

mRNA-based therapeutics and vaccines are the new hope in the fight against incurable diseases. A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the destruction of disease-causing mRNA.

16 Oct 2024

UCLA and Parker Institute renew alliance to advance cancer immunotherapy

UCLA and the Parker Institute for Cancer Immunotherapy (PICI) have renewed their alliance to advance research in cancer immunotherapy and accelerate the development of curative treatments for the most difficult-to-treat cancers.

16 Oct 2024

Two programs found to control invasion and inflammation in segregated tumor cell populations

Understanding in depth how tumors evolve to become malignant is the objective of the latest study led by the Cell Plasticity in Development and Disease laboratory, directed by ángela Nieto at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche.

16 Oct 2024

Gene editing restores treatment sensitivity in melanoma

In a potential advance for melanoma patients, researchers at ChristianaCare’s Gene Editing Institute have used CRISPR gene editing tools to disable a gene mutation often seen in aggressive forms of this dangerous skin cancer that renders promising treatments ineffective.

16 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

Experimental drug RK-33 shows promise in treating breast cancer bone metastasis

In a new study led by Johns Hopkins Medicine, the drug RK-33 has demonstrated promise in treating breast cancer that has spread to the bone (breast cancer bone metastasis). RK-33 was previously shown to help treat other types of cancer and viral illnesses.

15 Oct 2024

SU2C announces grants to support cutting-edge research in a variety of cancers

Stand Up To Cancer (SU2C) today announced grants to several teams of leading cancer investigators in support of cutting-edge research in a variety of cancers including head and neck, pediatric, pancreatic, breast, rectal and gastro-esophageal cancers, as well as research focused on how the microbiome communicates with the immune system.

15 Oct 2024

Extrachromosomal DNA in more aggressive cancers could be targets for future therapies

Research published in Nature Genetics on Oct.14, by Yale Cancer Center researchers at Yale School of Medicine, found a higher concentration of a specific kind of DNA — extrachromosomal or ecDNA — in more aggressive and advanced cancers that could mark them as targets for future therapies.

15 Oct 2024

Innovative bacteria-based therapy shows promise against cancer

Even as cancer remains a leading cause of death globally, bacteria-based cancer therapy presents an exciting and innovative treatment option.

15 Oct 2024

Breakdancer’s scalp mass removed after years of headspin injuries

Breakdancers can develop a fibrous mass on the scalp, known as the headspin hole, due to repetitive headspins. A recent BMJ Case Report details a case where surgery effectively removed the mass, alleviating symptoms.

14 Oct 2024

University of Michigan receives $30 million grant to enhance genetic data storage

The University of Michigan will dramatically boost the amount and type of genetic information stored in its massive TOPMed data center and used by researchers and healthcare providers around the world looking to genomes to treat disease.

14 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024

Chronic stress disrupts gut microbiota, promoting colorectal cancer growth

Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

13 Oct 2024

How gut microbiome and fiber diversity shape chronic disease outcomes

Review explores how different types of dietary fibers interact with the gut microbiome, influencing chronic disease risks like obesity, cancer, and cardiometabolic conditions, while emphasizing the need for personalized dietary interventions.

13 Oct 2024