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Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) - the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

Researchers evaluated the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the peripheral nervous system (PNS).

13 Jan 2023

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

A recent study evaluated outcomes in mechanically ventilated patients with pneumonia due to COVID-19 or other etiologies.

13 Jan 2023

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether commensal rodent pests such as rats and mice, sourced from sewers and urban settings, are exposed to and are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They also investigated viruses present in commensal rodents.

12 Jan 2023

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

One of the most dreaded effects of the bite of the brown recluse spider (Loxosceles spp) is the appearance of a necrotic skin lesion, but a clinical study by Brazilian researchers recently reported in PLOS Neglected Tropical Diseases shows that the problem can be solved by administering antivenom, especially if this is done within 48 hours of the incident.

11 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Study suggests a link between the protein-coding gene TREM2 and obesity in females

A recent Scientific Reports study has investigated the link between TREM2 expression and human obesity, based on two large public datasets, namely, the UK Biobank (UKB) and the Genotype-Tissue Expression (GTEx) project.

11 Jan 2023

Study may help explain how excess weight can contribute to diabetes

People who are overweight or obese have a significantly increased risk of developing diabetes, but exactly how that happens is not well understood.

11 Jan 2023

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Researchers investigated the efficacy of a booster dose of the bivalent mRNA COVID-19 vaccine in preventing severe outcomes during SARS-CoV-2 infections.

11 Jan 2023

Healthy eating patterns associated with reduced risk of premature mortality

A variety of healthy eating patterns are linked to reduced risk of premature death, according to a new study led by Harvard T.H. Chan School of Public Health researchers.

9 Jan 2023

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

In a recent study posted to the bioRxiv* preprint server, researchers at Emory University used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Washington (WA.1) and Omicron (BA.1) strains to test for mutations that could result in resistance to the antiviral drug nirmatrelvir.

8 Jan 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Researchers develop a new approach to better understand the biology of polycystic kidney disease

A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), an often-life-threatening genetic disorder that affects millions worldwide.

5 Jan 2023

Early intervention key to managing diabetes, cardiorenal, and metabolic diseases

A panel of US-based experts in cardiology, nephrology, endocrinology, and primary care has prepared specific recommendations for early identification and intervention in obesity, diabetes, and other cardiorenal and metabolic diseases. A detailed report on recommended strategies has been published in the Journal of Diabetes and its Complications.

4 Jan 2023

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

A team from 15 U.S. medical centers led by UT Southwestern Simmons Cancer Center researchers has performed the first analysis of a potentially game-changing drug to treat upper urinary tract urothelial cancers.

4 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Analyzing electronic medical records to identify COVID-19 sequelae

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed and compared pre‒ and post‒COVID-19 diagnostic codes to identify symptoms that had higher encounter incidence in the post‒COVID-19 period as sequelae. COVID-19 sequelae and future emerging diseases can be generated and monitored using this method.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Kidney News and Research

Targeting T cell iron metabolism may offer a new approach for treating lupus

Valuable tool reveals the connections between gut microbes and the brain

SARS-CoV-2 WA1/2020, Delta and Omicron strains found to infect human sensory neurons

Does COVID-19 pneumonia have a higher mortality rate than other causes of pneumonia?

Study on the ecology of viruses in urban rodents with special emphasis on SARS-CoV-2

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Study suggests a link between the protein-coding gene TREM2 and obesity in females

Study may help explain how excess weight can contribute to diabetes

Real-world effectiveness of the bivalent vaccine for preventing COVID-19 hospitalizations in non-hospitalized subjects

Healthy eating patterns associated with reduced risk of premature mortality

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems

CU researchers discover a new mechanism for slowing cardiac fibrosis

Sugar appears to play a role in polycystic kidney disease, study finds

Researchers develop a new approach to better understand the biology of polycystic kidney disease

Early intervention key to managing diabetes, cardiorenal, and metabolic diseases

Study shows the potential of a game-changing drug to treat upper urinary tract urothelial cancers

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Analyzing electronic medical records to identify COVID-19 sequelae

Researchers identify novel gene mechanism in most aggressive kidney cancers

Event guide: 8th CKD Summit 2026 eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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