Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Cysteine persulfide found to be a new culprit in antibacterial resistance

A joint research project based in Kumamoto University, Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections.

9 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Today's FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer's disease reflects years of significant advances in Alzheimer's research. This is the first new Alzheimer's drug approved in 17 years and the first shown to modify the course of the disease, which FDA believes will lead to slowing of patients' cognitive decline.

8 Jun 2021

ACE2 functions as a gateway for COVID-19 virus

Normally, the ACE2 enzyme helps regulate our blood pressure. The enzyme sits on the surface of cells, including cells in the lungs, but in connection with COVID-19 it has been found that ACE2 also functions as a gateway for the virus.

8 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Beckman Coulter launches new Access AMH Advanced assay to predict poor ovarian response

Beckman Coulter, a global leader in diagnostics and infertility testing, announced today the launch of the first and only test that uses a validated cut-off to aid in the assessment of ovarian response.

7 Jun 2021

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer.

5 Jun 2021

Mast cell activation may underlie inflammation in severe COVID-19

A new preprint research paper posted to the medRxiv* server points to mast cells as major culprits in the etiology of severe and critical COVID-19. This could suggest suitable therapeutic and preventive interventions to reduce the morbidity and mortality of this viral illness.

3 Jun 2021

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Children's Hospital Los Angeles has been awarded a $2 million grant from the state of California to study a precision medicine approach to screening children for adverse childhood experiences.

3 Jun 2021

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Airway mucus consists of various proteins such as long mucins MUC5AC and MUC5B, both of which contribute greatly to the proper gel-like consistency of this most essential bodily fluid.

3 Jun 2021

Could semen quality indicate SARS-CoV-2 insult susceptibility in polluted areas?

In a recent review in Environmental Science and Pollution Research, Italian researchers focused on “the evidence that correlates the degree and type of pollution with the increased susceptibility of many countries to this pandemic and proposes human semen as an early marker of the environmental health and the general health of individuals.” Their observations are based on a robust body of experimental evidence.

2 Jun 2021

SWOG researchers to present practice-changing research at virtual ASCO 2021

"SWOG always brings an impressive portfolio of work to the ASCO annual meeting," said SWOG Chair Charles D. Blanke, MD, "and this year I'm particularly excited about the research our investigators are presenting because it includes results that are likely to be practice-changing."

1 Jun 2021

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

The routine use of the glycosylated hemoglobin test to track blood sugar levels in the general population can identify individuals with more advanced atherosclerotic disease.

1 Jun 2021

New electromechanical device can help detect skin disorders non-invasively

By putting a piece of soft, strain-sensing sheet on the skin may be able to detect skin disorders non-invasively and in real-time very soon. A research team co-led by a scientist from City University of Hong Kong (CityU) has designed a simple electromechanical device that can be used for deep tissue pathology diagnosis, such as psoriasis, in an automated and non-invasive fashion.

29 May 2021

Researchers assess the prognostic value of cardiac troponin I in COVID-19 patients

Corona Virus Disease (COVID -19) patients primarily appear with respiratory issues and viral pneumonia. The patients may also present cardiovascular issues includes early signs of acute myocardial injury.

29 May 2021

Study explains why it is difficult to withdraw from certain antidepressants

Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications.

28 May 2021

New biomarker could be used to determine resistance of ovarian cancer to platinum chemotherapy

Epithelial ovarian cancer (EOC) is the most common lethal gynaecological cancer. Ovarian cancer is usually treated with platinum-based chemotherapy; however, a significant number of patients are resistant to such treatments and relapse soon afterwards.

28 May 2021

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

Alzheimer's disease - also called dementia - where memory and cognitive functions gradually decline due to deformation and death of neurons, and Parkinson's disease that causes tremors in hands and arms impeding normal movement are major neurodegenerative diseases.

26 May 2021

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

A new study aims to identify antibody-based biomarkers associated with the humoral immune response that could be a standard CoP candidate for COVID-19. Further, standardization of research methods to measure these biomarkers has also been conducted.

25 May 2021

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Antibodies, Antibody, Assay, Coronavirus, Efficacy, Healthcare, Pandemic, Protein, Receptor, Research, Vaccine, Virus, Coronavirus Disease COVID-19,

24 May 2021

Biomarker News and Research

Further Reading

Cysteine persulfide found to be a new culprit in antibacterial resistance

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

ACE2 functions as a gateway for COVID-19 virus

A single blood-based biomarker can help indicate underlying neurodegeneration

Beckman Coulter launches new Access AMH Advanced assay to predict poor ovarian response

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

Mast cell activation may underlie inflammation in severe COVID-19

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Could semen quality indicate SARS-CoV-2 insult susceptibility in polluted areas?

SWOG researchers to present practice-changing research at virtual ASCO 2021

Glycosylated hemoglobin can provide a useful estimate of atherosclerosis and cardiovascular events

New electromechanical device can help detect skin disorders non-invasively

Researchers assess the prognostic value of cardiac troponin I in COVID-19 patients

Study explains why it is difficult to withdraw from certain antidepressants

New biomarker could be used to determine resistance of ovarian cancer to platinum chemotherapy

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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